Citramon P tab. # 20 Renewal

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SKU
OTC1020132
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Category

Pain relievers

,

Migraine

Scope of the drug

General

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

twenty

Description

Release form, composition and packaging

Pills

1 tab.

acetylsalicylic acid

240 mg

paracetamol

180 mg

caffeine

30 mg

10 pieces.

- non-cell contoured packaging (1) - cardboard packs.

10 pieces.

- non-cell contoured packaging (2) - cardboard packs.

10 pieces.

- non-cell contoured packaging (3) - cardboard packs.

10 pieces.

- non-cell contoured packaging (5) - cardboard packs.

10 pieces.

- contour cell packaging (1) - cardboard packs.

10 pieces.

- contour cell packages (2) - cardboard packs.

10 pieces.

- contour cell packages (3) - cardboard packs.

10 pieces.

- contour cell packaging (5) - cardboard packs.

pharmachologic effect

Combined drug.

Acetylsalicylic acid has antipyretic and anti-inflammatory effects, relieves pain, especially caused by the inflammatory process, and also moderately inhibits platelet aggregation and thrombus formation, improves microcirculation in the focus of inflammation.

Caffeine increases the reflex excitability of the spinal cord, stimulates the respiratory and vasomotor centers, dilates the blood vessels of skeletal muscles, brain, heart, kidneys, and reduces platelet aggregation

reduces drowsiness, fatigue, increases mental and physical performance.

In this combination, a small dose of caffeine has practically no stimulating effect on the central nervous system, however, it helps to normalize the tone of the cerebral vessels and accelerate blood flow.

Paracetamol has an analgesic, antipyretic and extremely weak anti-inflammatory effect, which is associated with its effect on the center of thermoregulation in the hypothalamus and a weakly expressed ability to inhibit the synthesis of prostaglandins in peripheral tissues.

''

Indications for use

Pain syndrome of mild and moderate severity (of various origins): headache

migraine

toothache

neuralgia

myalgia

arthralgia

algodismenorrhea.

Feverish syndrome: with acute respiratory infections

with the flu.

Contraindications for use

Hypersensitivity to drug components

erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase)

gastrointestinal bleeding

aspirin" asthma

hemophilia

hemorrhagic diathesis

hypoprothrombinemia

portal hypertension

vitamin deficiency K

renal failure

I and III trimesters of pregnancy

lactation period (breastfeeding)

deficiency of glucose-6-phosphate dehydrogenase

severe arterial hypertension

severe course of ischemic heart disease

glaucoma

increased excitability

sleep disorders

surgical interventions accompanied by bleeding

children's age (up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia against the background of viral diseases).

With care: gout, liver disease.

Dosage regimen

Inside (during or after meals) take every 4 hours. On average, take 3-4 times / day.

The maximum frequency of admission is 8 times / day.

The course of treatment is no more than 7-10 days.

In case of impaired renal or liver function, the interval between doses is at least 6 hours.

The drug should not be taken for more than 5 days when prescribed as an anesthetic and more than 3 days as an antipyretic.

Other doses and regimens are determined by the doctor.

Side effect

From the digestive system: gastralgia, nausea, vomiting, hepatotoxicity, erosive and ulcerative lesions of the gastrointestinal tract.

From the urinary system: nephrotoxicity,

Allergic reactions: skin manifestations, Stevens-Johnson syndrome, Lyell's syndrome, bronchospasm.

From the side of the cardiovascular system: tachycardia, increased blood pressure,

With prolonged use: dizziness, headache, visual disturbances, tinnitus, decreased platelet aggregation, hypocoagulation, hemorrhagic syndrome (including nosebleeds, bleeding gums, purpura and), kidney damage with papillary necrosis

deafness

Reye's syndrome in children (hyperpyrexia, metabolic acidosis, disorders of the nervous system and psyche, vomiting, liver dysfunction).

Drug interactions

Strengthens the action of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic drugs.

Concomitant administration with other NSAIDs, methotrexate increases the risk of side effects.

Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as anti-gout drugs that promote the excretion of uric acid.

Barbiturates, rifampicin, salicylamide, antiepileptic drugs and other stimulants of microsomal oxidation contribute to the formation of toxic paracetamol metabolites that affect liver function.

Metoclopramide accelerates the absorption of paracetamol.

Under the influence of paracetamol, T1 / 2 of chloramphenicol increases by 5 times.

With repeated administration, paracetamol can enhance the effect of anticoagulants (dicoumarin derivatives).

The simultaneous use of paracetamol and ethanol increases the risk of developing hepatotoxic effects.

Caffeine accelerates the absorption of ergotamine.

Application during pregnancy and lactation

Use is contraindicated in the I and III trimesters of pregnancy and during lactation (breastfeeding).

Acetylsalicylic acid has a teratogenic effect

when used in the first trimester of pregnancy, it leads to a developmental defect - splitting of the upper palate

in the third trimester - to inhibition of labor (inhibition of prostaglandin synthesis), to the closure of the ductus arteriosus in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation.

It is excreted in breast milk, which increases the risk of bleeding in a child due to impaired platelet function.

Special instructions Children should not be prescribed medicines containing acetylsalicylic acid, since in the case of a viral infection, they can increase the risk of Reye's syndrome.

Symptoms of Reye's syndrome are prolonged vomiting, acute encephalopathy, and enlarged liver.

With prolonged use of the drug, it is necessary to monitor the peripheral blood and the functional state of the liver.

Since acetylsalicylic acid slows down blood clotting, the patient, if he is to undergo surgery, must warn the doctor in advance about taking the drug.

Patients with hypersensitivity or with asthmatic reactions to salicylates or their derivatives, acetylsalicylic acid can only be prescribed with special precautions (in an emergency room).

Acetylsalicylic acid in low doses reduces the excretion of uric acid.

In patients with a corresponding predisposition, this can in some cases provoke an attack of gout.

During treatment, you should stop using ethanol (increased risk of gastrointestinal bleeding).

Name ENG

CITRAMON P

Clinical and pharmacological group

Combined analgesic-antipyretic.

ATX code

Acetylsalicylic acid in combination with psycholeptics.

Dosage

240mg + 30mg + 180mg

Structure

1 tab.

acetylsalicylic acid 240 mg

paracetamol 180 mg

caffeine (in terms of monohydrate) 30 mg. Excipients: cocoa powder - 22.5 mg, citric acid monohydrate - 5 mg, potato starch - 64.2 mg, talc - 4.9 mg, calcium stearate - 2.8 mg, polysorbate 80 - 0.6 mg.

Indications

Pain syndrome of mild and moderate severity (of various origins): headache

migraine

toothache

neuralgia

myalgia

arthralgia

algodismenorrhea.

Feverish syndrome: with acute respiratory infections

with the flu.

INN / Active ingredient

Caffeine + Paracetamol + Acetylsalicylic Acid

Contraindications

Hypersensitivity to drug components

erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase)

gastrointestinal bleeding

"aspirin" asthma

hemophilia

hemorrhagic diathesis

hypoprothrombinemia

portal hypertension

vitamin deficiency K

renal failure

I and III trimesters of pregnancy

lactation period (breastfeeding)

deficiency of glucose-6-phosphate dehydrogenase

severe arterial hypertension

severe course of ischemic heart disease

glaucoma

increased excitability

sleep disorders

surgical interventions accompanied by bleeding

children's age (up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia against the background of viral diseases).

With care: gout, liver disease.

Storage conditions and periods

In a dry place, at a temperature not exceeding 25 degrees.

Expiration date: 4 years

Specifications

Category

Pain relievers

,

Migraine

Scope of the drug

General

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

twenty

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Renewal

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Dosage form

Pills

Expiration date in days

1460

Package weight, g

thirty

Mode of application

:

Inside (during or after meals), 1 tab.

every 4 hours, with pain, 1-2 tab.

the average daily dose is 3-4 tablets, the maximum daily dose is 8 tablets.

The use of the drug is not more than 7-10 days. < br> < br> To reduce the irritating effect on the gastrointestinal tract, take the tablet with milk or alkaline mineral water.

In case of impaired renal or liver function, the interval between doses is at least 6 hours.

The drug should not be taken for more than 5 days when prescribed as an anesthetic and more than 3 days as an antipyretic.

Other doses and regimens are determined by the doctor.

Pharmaco-therapeutic group

:

Combined analgesic agent (NSAIDs + non-narcotic analgesic agent + psychostimulating agent)

Anatomical and therapeutic characteristics

:

N02BA71 Acetylsalicylic acid, in combination with psychotropic drugs

Dosage (volume) of the substance in the preparation

:

acetylsalicylic acid 240 mg, paracetamol 180 mg, caffeine 30 mg

Information on technical characteristics, delivery set, country of manufacture "

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