Citramon P tab. �20 Renewal

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OTC1020131
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Category

Pain relievers

,

Migraine

Scope of the drug

General

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

twenty

Description

DESCRIPTION: White or grayish-white tablets in the form of a beveled disc, with “SUPRASTIN” engraving on one side of the tablet and a scoring on the other side, without or almost odorless.

Pharmacodynamics

Chloropyramine, a chlorinated analogue of tripelenamine (pyribenzamine), is a classic antihistamine that belongs to the group of ethylenediamine antihistamines.

Blocker of H1-histamine receptors, has antihistamine and m-anticholinergic action, has an antiemetic effect, moderate antispasmodic and peripheral anticholinergic activity.

Pharmacokinetics

When taken orally, it is almost completely absorbed from the gastrointestinal tract (GIT).

The therapeutic effect of chloropyramine develops within 15 to 30 minutes after ingestion, reaches a maximum within the first hour after ingestion and lasts at least 3 to 6 hours.

Well distributed in the body, including the central nervous system (CNS).

It is extensively metabolized in the liver.

It is excreted mainly by the kidneys.

In children, the elimination of the drug is faster than in adult patients.

Indications

Urticaria, serum sickness, seasonal and perennial allergic rhinitis, conjunctivitis, contact dermatitis, pruritus, acute and chronic eczema, atopic dermatitis, food and drug allergies, allergic reactions to insect bites.

Angioedema (Quincke's edema) as an adjuvant.

Contraindications

hypersensitivity to drug components,

acute attack of bronchial asthma,

children's age up to 3 years (for this dosage form),

pregnancy and lactation,

lactase deficiency, lactose intolerance, glucose / galactose malabsorption (since the tablet contains 116 mg of lactose monohydrate).

With care: angle-closure glaucoma, urinary retention, prostatic hyperplasia, impaired liver and / or kidney function, cardiovascular disease, elderly patients.

Pregnancy and the period of breastfeeding:

There have been no adequate, well-controlled studies of the use of antihistamines in pregnant women.

Accordingly, taking chloropyramine during pregnancy is contraindicated.

The drug should not be used during breastfeeding.

If it is necessary to use the drug during lactation, the issue of suspending breastfeeding should be resolved.

DOSAGE AND APPLICATION

The tablets are taken orally with meals, without chewing and drinking plenty of water.

Adults: appoint 1 tablet 3-4 times a day (75-100 mg per day).

Children:

At the age of 3 to 6 years: 1/2 tablet 2 times a day

From 6 to 14 years old: 1/2 tablet (12.5 mg) 2-3 times a day.

The dose can be gradually increased in the absence of side effects in the patient, but the maximum dose should never exceed 2 mg / kg body weight.

The duration of the course of treatment depends on the symptoms of the disease, its duration and course.

Special patient groups:

Elderly, emaciated patients: the use of the drug Suprastin requires special care, because

in these patients, antihistamines are more likely to cause side effects (dizziness, drowsiness).

Patients with impaired liver function: a dose reduction may be required due to a decrease in the metabolism of the active component of the drug in liver diseases.

Patients with impaired renal function: it may be necessary to change the regimen of the drug and reduce the dose due to the fact that the active component is mainly excreted through the kidneys.

SIDE EFFECT

Side effects, as a rule, occur extremely rarely, are temporary, and disappear after the drug is discontinued.

From the side of the blood and lymphatic system: very rarely: leukopenia, agranulocytosis, hemolytic anemia and other changes in the cellular composition of the blood.

From the side of the central nervous system: drowsiness, fatigue, dizziness, nervous agitation, tremors, headache, euphoria, convulsions, encephalopathy.

From the side of the organ of vision: blurred vision, glaucoma, increased intraocular pressure.

From the side of the cardiovascular system: lowering blood pressure, tachycardia, arrhythmia.

A direct relationship of these side effects with the drug intake has not always been established.

From the gastrointestinal tract: abdominal discomfort, dry mouth, nausea, vomiting, diarrhea, constipation, loss or increased appetite, pain in the upper abdomen.

Musculoskeletal and connective tissue disorders: muscle weakness.

From the kidneys and urinary tract: difficulty urinating, urinary retention.

Others: photosensitivity, allergic reactions.

If any of the above effects occur, you should stop taking the drug and immediately consult a doctor.

Overdose

Symptoms: hallucinations, anxiety, ataxia, impaired coordination of movements, athetosis, convulsions.

In young children, agitation, anxiety, dry mouth, fixed dilated pupils, facial flushing, sinus tachycardia, urinary retention, fever, coma.

In adults, fever and facial flushing are observed intermittently, after a period of excitement, convulsions and post-convulsive depression, coma follow.

Treatment: in the period up to 12 hours after taking the drug, gastric lavage is necessary (it should be borne in mind that the anticholinergic effect of the drug prevents gastric emptying).

The use of activated carbon is also shown.

It is necessary to control the parameters of blood pressure and respiration.

Symptomatic therapy.

Resuscitation measures.

No specific antidote is known.

INTERACTIONS WITH OTHER MEDICINAL PRODUCTS

The drug enhances the action of drugs: barbiturates, M-anticholinergics, opioid analgesics.

MAO inhibitors can enhance and prolong the anticholinergic effect of chloropyramine.

When combined with ototoxic drugs, Suprastin can mask early signs of ototoxicity.

Antihistamines can distort the results of allergy skin tests, so you should stop taking this type of drug a few days before the planned test.

SPECIAL INSTRUCTIONS

When combined with ototoxic drugs, Suprastin can mask early signs of ototoxicity.

Diseases of the liver and kidneys may require a change (decrease) in the dose of the drug, in connection with which the patient should inform the doctor about the presence of liver or kidney disease.

Taking the drug at night can increase the symptoms of reflux esophagitis.

Suprastin can enhance the effect of alcohol on the central nervous system, and therefore, while taking the drug Suprastin, alcohol should be avoided.

Long-term use of antihistamines can lead to disorders of the blood and hematopoietic system (leukopenia, agranulocytosis, thrombocytopenia, hemolytic anemia). If during prolonged use there is an unexplained increase in body temperature, laryngitis, pallor of the skin, jaundice, the formation of mouth ulcers, the appearance of hematomas, unusual and prolonged bleeding, it is necessary to conduct a clinical blood test to determine the number of formed elements. If the test results indicate a change in the blood count, the drug is stopped.

Influence of a medicinal product for medical use on the ability to drive vehicles, mechanisms: The drug, especially in the initial period of treatment, may cause drowsiness, fatigue and dizziness.

Therefore, in the initial period, the duration of which is determined individually, it is prohibited to drive vehicles or perform work associated with an increased risk of accidents.

After that, the doctor must determine the degree of restriction on driving vehicles and working with mechanisms for each patient individually.

Release form

25 mg tablets.

20 tablets in brown glass vials with PE cap.

The bottle is packed in a cardboard box along with instructions for medical use.

10 tablets in a blister.

2 or 4 blisters in a cardboard box together with instructions for medical use.

There are 20 tablets in a blister.

1 blister in a cardboard box along with instructions for medical use.

Name ENG

SUPRASTIN

Clinical and pharmacological group

Blocker of histamine H1 receptors.

Antiallergic drug.

ATX code

Chloropyramine

Dosage

25mg

Structure

1 tablet contains chloropyramine hydrochloride 25 mg excipients: lactose, starch, talc, sodium amylopectin, gelatin, stearic acid.

Indications

Allergic diseases (including urticaria, serum sickness, pollinosis, or hay fever, rhinitis, conjunctivitis)

anaphylactic shock and angioedema

skin diseases (including contact dermatitis, acute and chronic eczema, neurodermatitis, toxicoderma)

prevention and treatment of allergic and pseudoallergic reactions to drugs and diagnostic drugs

itching and insect bites

ARVI.

Contraindications

hypersensitivity to drug components

acute attack of bronchial asthma

children under 3 years of age (for this dosage form)

lactase deficiency, lactose intolerance, glucose / galactose malabsorption (since the tablet contains 116 mg of lactose monohydrate)

pregnancy

lactation period.

With care: angle-closure glaucoma

retention of urine

hyperplasia of the prostate

impaired liver and / or kidney function

cardiovascular diseases

elderly patients.

INN / Active ingredient

Chloropyramine

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 5 years

Specifications

Category

Allergy

Scope of the drug

General

Release form

Tablet

Manufacturer country

Hungary

Package quantity, pcs

twenty

Minimum age from

1 month

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Egis

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

R06AC03 Chloropyramine

Dosage form

Pills

The target audience

Children

Dosage (volume) of the substance in the preparation

chloropyramine hydrochloride 25 mg

Expiration date in days

1825

Package weight, g

twenty

Mode of application

:

Adults are prescribed 25 mg (1 tab.) 3-4 times a day (75-100 mg / day). < br> < br> Children aged 1-12 months are prescribed 1/4 tab.

(6.25 mg) 2-3 times a day (in powder form together with baby food)

2-6 years old - 1/3 tab.

(8.3 mg) 2-3 times a day

7-14 years old - 1/2 tab.

(12.5 mg) 3 times a day. < br> < br> Tablets should be taken after meals.

Pharmaco-therapeutic group

:

Antiallergic agent - H1-histamine receptor blocker https://translate.google.com/translate?hl=&sl=ru&tl=en&u=https://zz.buy-pharm.com/xzzajtq.html;Description

Release form, composition and packaging

Pills

1 tab.

acetylsalicylic acid

240 mg

paracetamol

180 mg

caffeine

30 mg

10 pieces.

- non-cell contoured packaging (1) - cardboard packs.

10 pieces.

- non-cell contoured packaging (2) - cardboard packs.

10 pieces.

- non-cell contoured packaging (3) - cardboard packs.

10 pieces.

- non-cell contoured packaging (5) - cardboard packs.

10 pieces.

- contour cell packaging (1) - cardboard packs.

10 pieces.

- contour cell packages (2) - cardboard packs.

10 pieces.

- contour cell packages (3) - cardboard packs.

10 pieces.

- contour cell packaging (5) - cardboard packs.

pharmachologic effect

Combined drug.

Acetylsalicylic acid has antipyretic and anti-inflammatory effects, relieves pain, especially caused by the inflammatory process, and also moderately inhibits platelet aggregation and thrombus formation, improves microcirculation in the focus of inflammation.

Caffeine increases the reflex excitability of the spinal cord, stimulates the respiratory and vasomotor centers, dilates the blood vessels of skeletal muscles, brain, heart, kidneys, and reduces platelet aggregation

reduces drowsiness, fatigue, increases mental and physical performance.

In this combination, a small dose of caffeine has practically no stimulating effect on the central nervous system, however, it helps to normalize the tone of the cerebral vessels and accelerate blood flow.

Paracetamol has an analgesic, antipyretic and extremely weak anti-inflammatory effect, which is associated with its effect on the center of thermoregulation in the hypothalamus and a weakly expressed ability to inhibit the synthesis of prostaglandins in peripheral tissues.

''

Indications for use

Pain syndrome of mild and moderate severity (of various origins): headache

migraine

toothache

neuralgia

myalgia

arthralgia

algodismenorrhea.

Feverish syndrome: with acute respiratory infections

with the flu.

Contraindications for use

Hypersensitivity to drug components

erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase)

gastrointestinal bleeding

"aspirin" asthma

hemophilia

hemorrhagic diathesis

hypoprothrombinemia

portal hypertension

vitamin deficiency K

renal failure

I and III trimesters of pregnancy

lactation period (breastfeeding)

deficiency of glucose-6-phosphate dehydrogenase

severe arterial hypertension

severe course of ischemic heart disease

glaucoma

increased excitability

sleep disorders

surgical interventions accompanied by bleeding

children's age (up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia against the background of viral diseases).

With care: gout, liver disease.

Dosage regimen

Inside (during or after meals) take every 4 hours. On average, take 3-4 times / day.

The maximum frequency of admission is 8 times / day.

The course of treatment is no more than 7-10 days.

In case of impaired renal or liver function, the interval between doses is at least 6 hours.

The drug should not be taken for more than 5 days when prescribed as an anesthetic and more than 3 days as an antipyretic.

Other doses and regimens are determined by the doctor.

Side effect

From the digestive system: gastralgia, nausea, vomiting, hepatotoxicity, erosive and ulcerative lesions of the gastrointestinal tract.

From the urinary system: nephrotoxicity,

Allergic reactions: skin manifestations, Stevens-Johnson syndrome, Lyell's syndrome, bronchospasm.

From the side of the cardiovascular system: tachycardia, increased blood pressure,

With prolonged use: dizziness, headache, visual disturbances, tinnitus, decreased platelet aggregation, hypocoagulation, hemorrhagic syndrome (including nosebleeds, bleeding gums, purpura and), kidney damage with papillary necrosis

deafness

Reye's syndrome in children (hyperpyrexia, metabolic acidosis, disorders of the nervous system and psyche, vomiting, liver dysfunction).

Drug interactions

Strengthens the action of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic drugs.

Concomitant administration with other NSAIDs, methotrexate increases the risk of side effects.

Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as anti-gout drugs that promote the excretion of uric acid.

Barbiturates, rifampicin, salicylamide, antiepileptic drugs and other stimulants of microsomal oxidation contribute to the formation of toxic paracetamol metabolites that affect liver function.

Metoclopramide accelerates the absorption of paracetamol.

Under the influence of paracetamol, T1 / 2 of chloramphenicol increases by 5 times.

With repeated administration, paracetamol can enhance the effect of anticoagulants (dicoumarin derivatives).

The simultaneous use of paracetamol and ethanol increases the risk of developing hepatotoxic effects.

Caffeine accelerates the absorption of ergotamine.

Application during pregnancy and lactation

Use is contraindicated in the I and III trimesters of pregnancy and during lactation (breastfeeding).

Acetylsalicylic acid has a teratogenic effect

when used in the first trimester of pregnancy, it leads to a developmental defect - splitting of the upper palate

in the third trimester - to inhibition of labor (inhibition of prostaglandin synthesis), to the closure of the ductus arteriosus in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation.

It is excreted in breast milk, which increases the risk of bleeding in a child due to impaired platelet function.

Special instructions Children should not be prescribed medicines containing acetylsalicylic acid, since in the case of a viral infection, they can increase the risk of Reye's syndrome.

Symptoms of Reye's syndrome are prolonged vomiting, acute encephalopathy, and enlarged liver.

With prolonged use of the drug, it is necessary to monitor the peripheral blood and the functional state of the liver.

Since acetylsalicylic acid slows down blood clotting, the patient, if he is to undergo surgery, must warn the doctor in advance about taking the drug.

Patients with hypersensitivity or with asthmatic reactions to salicylates or their derivatives, acetylsalicylic acid can only be prescribed with special precautions (in an emergency room).

Acetylsalicylic acid in low doses reduces the excretion of uric acid.

In patients with a corresponding predisposition, this can in some cases provoke an attack of gout.

During treatment, you should stop using ethanol (increased risk of gastrointestinal bleeding).

Name ENG

CITRAMON P

Clinical and pharmacological group

Combined analgesic-antipyretic.

ATX code

Acetylsalicylic acid in combination with psycholeptics.

Dosage

240mg + 30mg + 180mg

Structure

1 tab.

acetylsalicylic acid 240 mg

paracetamol 180 mg

caffeine (in terms of monohydrate) 30 mg. Excipients: cocoa powder - 22.5 mg, citric acid monohydrate - 5 mg, potato starch - 64.2 mg, talc - 4.9 mg, calcium stearate - 2.8 mg, polysorbate 80 - 0.6 mg.

Indications

Pain syndrome of mild and moderate severity (of various origins): headache

migraine

toothache

neuralgia

myalgia

arthralgia

algodismenorrhea.

Feverish syndrome: with acute respiratory infections

with the flu.

Contraindications

Hypersensitivity to drug components

erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase)

gastrointestinal bleeding

"aspirin" asthma

hemophilia

hemorrhagic diathesis

hypoprothrombinemia

portal hypertension

vitamin deficiency K

renal failure

I and III trimesters of pregnancy

lactation period (breastfeeding)

deficiency of glucose-6-phosphate dehydrogenase

severe arterial hypertension

severe course of ischemic heart disease

glaucoma

increased excitability

sleep disorders

surgical interventions accompanied by bleeding

children's age (up to 15 years - the risk of developing Reye's syndrome in children with hyperthermia against the background of viral diseases).

With care: gout, liver disease.

Storage conditions and periods

In a dry place, at a temperature not exceeding 25 degrees.

Expiration date: 4 years

INN / Active ingredient

Caffeine + Paracetamol + Acetylsalicylic Acid

Specifications

Category

Pain relievers

,

Migraine

Scope of the drug

General

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

twenty

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Renewal

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Dosage form

Pills

Expiration date in days

1460

Package weight, g

twenty

Mode of application

:

Inside (during or after meals), 1 tab.

every 4 hours, with pain, 1-2 tab.

the average daily dose is 3-4 tablets, the maximum daily dose is 8 tablets.

The use of the drug is not more than 7-10 days. < br> < br> To reduce the irritating effect on the gastrointestinal tract, take the tablet with milk or alkaline mineral water.

In case of impaired renal or liver function, the interval between doses is at least 6 hours.

The drug should not be taken for more than 5 days when prescribed as an anesthetic and more than 3 days as an antipyretic.

Other doses and regimens are determined by the doctor.

Pharmaco-therapeutic group

:

Combined analgesic agent (NSAIDs + non-narcotic analgesic agent + psychostimulating agent)

Anatomical and therapeutic characteristics

:

N02BA71 Acetylsalicylic acid, in combination with psychotropic drugs

Dosage (volume) of the substance in the preparation

:

acetylsalicylic acid 240 mg, paracetamol 180 mg, caffeine 30 mg

Information on technical characteristics, delivery set, country of manufacture "

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