Ciprofloxacin | Ciprofloxacin tablets 500 mg, 10 pcs.

Special Price $12.61 Regular Price $21.00
In stock
SKU
BID471207
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Latin name

Ciprofloxacin
Latin name

Ciprofloxacin

release form

film-coated tablets

Packing

In a package of 500 mg tablets 10pcs.

Indications

Infectious and inflammatory diseases caused by microorganisms sensitive to the drug: - airways

- ear, nose and throat

- kidneys and urinary tract

- genitals (including gonorrhea, prostate - srd) including adnexitis) and postpartum infections of

- the digestive system (including the oral cavity, teeth, jaws)

- gall bladder and biliary tract

- skin, mucous membranes and soft tissues

- musculoskeletal system

k - seps peritonitis

Prevention and treatment of infections in patients with reduced immunity (in the treatment of immunosuppressants).

Contraindications

- glucose-6-phosphate dehydrogenase deficiency

- pseudocarcinoma skeletal formation process)

- pregnancy

- lactation (breastfeeding)

- hypersensitivity to ciprofloxacin or other drugs from the fluoroquinolone group.

With caution, the drug should be prescribed for severe cerebral arteriosclerosis, cerebrovascular accident, mental illness, convulsive syndrome, epilepsy, severe renal and / or liver failure, elderly patients.

Use during pregnancy and lactation

Ciprofloxacin is contraindicated in pregnancy and lactation (breastfeeding).

Dosage and administration

The dose of ciprofloxacin depends on the severity of the disease, the type of infection, the condition of the body, age, weight and kidney function in the patient. Usually recommended doses: Ciprofloxacin in the dosage form, tablets of 250 mg and 500 mg for oral administration: Uncomplicated diseases of the kidneys and urinary tract - 250 mg, and in complicated cases - 500 mg. 2 times a day

Diseases of the lower respiratory tract of moderate severity - 250 mg, and in more severe cases - 500 mg, 2 times a day

For the treatment of gonorrhea, a single dose of ciprofloxacin is recommended at a dose of 250-500 mg

Gynecological diseases, enteritis and severe colitis and fever, prostatitis, osteomyelitis - 500 mg 2 times a day (for the treatment of banal diarrhea, you can use a dose of 250 mg 2 times a day).

The drug should be taken on an empty stomach, drinking plenty of fluids. Patients with severe renal impairment should be prescribed a half dose of the drug. The duration of treatment depends on the severity of the disease, but treatment should always continue for at least two more days after the disappearance of the symptoms of the disease. Typically, the duration of treatment is 7-10 days.

Side effects of the

Digestive system: nausea, diarrhea, vomiting, abdominal pain, flatulence, anorexia, cholestatic jaundice (especially in patients with past liver diseases), hepatitis, hepatonecrosis.

From the side of the central nervous system and peripheral nervous system: dizziness, headache, fatigue, anxiety, tremors, insomnia, nightmares, peripheral paralgesia (anomaly in the perception of pain), sweating, increased intracranial pressure, anxiety, confusion, depression, hallucinations manifestations of psychotic reactions (sometimes progressing to conditions in which the patient may harm himself), migraine, fainting, cerebral artery thrombosis.

On the part of the sensory organs: impaired taste and smell, impaired vision (diplopia, color perception), tinnitus, hearing loss.

From the cardiovascular system: tachycardia, cardiac arrhythmias, decreased blood pressure, flushing of the face.

From the hematopoietic system: leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia.

On the part of laboratory parameters: hypoprothrombinemia, increased activity of hepatic transaminases and alkaline phosphatase, hypercreatininemia, hyperbilirubinemia, hyperglycemia.

From the urinary system: hematuria, crystalluria (primarily with alkaline urine and low diuresis), glomerulonephritis, dysuria, polyuria, urinary retention, albuminuria, urethral bleeding, hematuria, decreased kidney excretory function, interstitial nephritis.

From the musculoskeletal system: arthralgia, arthritis, tendovaginitis, tendon ruptures, myalgia.

Allergic reactions: skin itching, urticaria, the formation of blisters accompanied by bleeding, papules forming scabs, drug fever, spot hemorrhages (petechiae), swelling of the face or larynx, shortness of breath, eosinophilia, increased photosensitivity, vasculitis, erythematosus, erythema erythema Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).

Local reactions: pain and burning at the injection site, phlebitis.

Other: general weakness, superinfection (candidiasis, pseudomembranous colitis).

Drug Interaction

Due to the decreased activity of microsomal oxidation processes in hepatocytes, ciprofloxacin increases the concentration and prolongs the half-life of theophylline and other xanthines (eg caffeine), oral hypoglycemic drugs, oral hypoglycemic drugs, oral hypoglycemic drugs,

When used with NSAIDs (except acetylsalicylic acid), the risk of seizures is increased.

Metoclopramide accelerates the absorption of ciprofloxacin, leading to a decrease in the time to reach the maximum concentration of the latter.

Co-administration of uricosuric drugs leads to a slowing of elimination (up to 50%) and an increase in the plasma concentration of ciprofloxacin.

When combined with other antimicrobials (beta-lactam antibiotics, aminoglycosides, clindamycin, metronidazole), synergism is usually observed. Therefore, Ciprofloxacin can be successfully used in combination with azlocillin and ceftazidime in infections caused by Pseudomonas spp. with mesocillin, azlocillin and other beta-lactam antibiotics - for streptococcal infections with isoxazolpenicillins and vancomycin - for staphylococcal infections with metronidazole and clindamycin - for anaerobic infections.

Ciprofloxacin enhances the nephrotoxic effect of cyclosporine, and there is also an increase in serum creatinine, so such patients need to be monitored twice a week.

When administered with Ciprofloxacin enhances the effect of indirect anticoagulants.

Pharmaceutical Interaction

The infusion solution of the drug is pharmaceutically incompatible with all infusion solutions and preparations that are physically and chemically unstable in acidic media (pH of the ciprofloxacin infusion solution - 3.5-4.6). Do not mix solution for I / O with solutions having a pH greater than 7.



overdose Use as

infusion Symptoms: nausea, vomiting, confusion, mental arousal.

Treatment: The specific antidote is unknown. It is necessary to carefully monitor the patient's condition, conduct symptomatic therapy, ensure sufficient fluid intake. To prevent the development of crystalluria, it is recommended to monitor kidney function, including the acidity (pH) of urine.

Oral use

Symptoms: dizziness, tremor, headache, fatigue, seizures, hallucinations, QT lengthening, gastrointestinal disorders, impaired liver and kidney function, crystalluria, hematuria.

Treatment: The specific antidote is unknown. Gastric lavage, activated carbon intake, calcium and magnesium-containing antacids to reduce ciprofloxacin absorption. For the prevention of crystalluria, monitoring of kidney function, including pH and urine acidity, is recommended. Symptomatic therapy. Careful monitoring of the patient's condition, ensuring sufficient fluid intake.

Only a small (less than 10%) amount of ciprofloxacin can be eliminated by hemo- or peritoneal dialysis.

Ophthalmic use

No overdose data. In case of unpleasant sensations in the eye area, it is recommended to wash the eyes with warm water.

Storage conditions

Store in a dark place at a temperature of 5 ° to 20 РC, out of the reach of children. Do not freeze!

Expiration

See. on the packaging.

Deystvuyuschee substances

Ciprofloxacin

Conditions of supply of

Pharmacy Prescription

dosage form

dosage form

tablets

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