Cholisal dental gel, 10g

For local use on the mucous membranes of the oral cavity as an analgesic and anti-inflammatory agent in the treatment of periodontal diseases, damage to the oral mucosa, diseases occurring with an inflammatory reaction and pain, including:

• stomatitis of various etiologies,

• gingivitis,

• periodontitis,

• damage to the oral mucosa when wearing dentures,

• trauma to the oral mucosa,

• teething pain in children,

• cheilitis,

• oral mucosa candidiasis,

• small surgical interventions in the oral cavity,

• lichen planus when localized on the mucous membrane of the mouth,

• damage to the oral mucosa in Stevens-Johnson syndrome as part of complex therapy.

Locally. CholisalЃ is used 2-3 times a day before meals (for pain relief) or after meals and before bedtime.
A strip of gel 1 cm long for adults and 0.5 cm for children is squeezed onto a clean finger and rubbed with light massaging movements into the affected area of ??the oral mucosa.
In case of periodontal diseases, the gel is injected into the pockets or applied in the form of compresses, or gently rubbed into the gums 1-2 times a day.

1 g contains:
active substance: choline salicylate - 87.1 mg, cetalkonium chloride - 0.1 mg.
excipients: hyetellose -20.0 mg, methyl parahydroxybenzoate - 1.5 mg, propyl parahydroxybenzoate - 0.8 mg, glycerol - 50.0 mg, anise seed oil - 1.61 mg, ethanol 96% - 390.0 mg, water - up to 1000 mg.

Hypersensitivity to salicylates and other components of the drug.
Carefully

pregnancy, lactation, children under 1 year of age.

Trade name of the drug:

HolisalЃ

International non-proprietary name:

Choline Salicylate + Cetalkonium Chloride

Dosage form:

dental gel

Composition:

1 g contains:
active substance: choline salicylate - 87.1 mg, cetalkonium chloride - 0.1 mg.
excipients: hyetellose -20.0 mg, methyl parahydroxybenzoate - 1.5 mg, propyl parahydroxybenzoate - 0.8 mg, glycerol - 50.0 mg, anise seed oil - 1.61 mg, ethanol 96% - 390.0 mg, water - up to 1000 mg.

Description:

Transparent colorless homogeneous mass with anise oil smell.

Pharmacotherapeutic group:

NSAIDs

ATX code:

A01AD11

Pharmacological properties

When applied topically, the main active ingredient of choline salicylate is rapidly absorbed through the oral mucosa, providing a local analgesic, anti-inflammatory and antipyretic effect.
It inhibits the activity of cyclooxygenase, the function of macrophages and neutrophils, the production of interleukin-1 and inhibits the synthesis of prostaglandins. It also has antimicrobial and antifungal effects (in acidic and alkaline environments).
Cetalkonium chloride - antiseptic, acts on 445R / 475R bacteria, as well as fungi and viruses. The ethanol-containing gel adhesive base provides a rapid development of the effect and retains the active substances on the mucous membrane for a long time. The analgesic effect occurs in 2-3 minutes, while its duration is 2-8 hours.

Pharmacokinetics
When applied to mucous membranes, it is well absorbed.

Indications for use

For local use on the mucous membranes of the oral cavity as an analgesic and anti-inflammatory agent in the treatment of periodontal diseases, damage to the oral mucosa, diseases occurring with an inflammatory reaction and pain, including:

• stomatitis of various etiologies,

• gingivitis,

• periodontitis,

• damage to the oral mucosa when wearing dentures,

• trauma to the oral mucosa,

• teething pain in children,

• cheilitis,

• oral mucosa candidiasis,

• small surgical interventions in the oral cavity,

• lichen planus when localized on the mucous membrane of the mouth,

• damage to the oral mucosa in Stevens-Johnson syndrome as part of complex therapy.

Contraindications

Hypersensitivity to salicylates and other components of the drug.

Carefully

Pregnancy, lactation, children under 1 year of age.

Method of administration and dosage

Locally. CholisalЃ is used 2-3 times a day before meals (for pain relief) or after meals and before bedtime.
A strip of gel 1 cm long for adults and 0.5 cm for children is squeezed onto a clean finger and rubbed with light massaging movements into the affected area of ??the oral mucosa.
In case of periodontal diseases, the gel is injected into the pockets or applied in the form of compresses, or gently rubbed into the gums 1-2 times a day.

Side effect

A short-term slight burning sensation in the places of application of the drug, passing on its own. Allergic reactions.

Overdose

No cases of an overdose of CholisalЃ have been identified.

Interaction with other medicinal products

When taking the drug CholisalЃ, it is possible to enhance the action of other anti-inflammatory, antipyretic and analgesic agents.

special instructions

When the first signs of a side effect of the drug appear, you must immediately inform your doctor about it.
Use the drug for topical use only. CholisalЃ does not contain sugar.

Influence on the ability to drive a vehicle and service moving machinery:

The drug does not limit psychophysical activity, the ability to drive vehicles and service moving mechanisms.

Release form

Dental gel.
10 g or 15 g each in aluminum tubes with a membrane and polymer caps (with an opponent).
The tube is placed in a cardboard box with instructions for use.

Storage conditions

At a temperature not higher than 25 ? C. Do not freeze.
Keep out of the reach of children.

Shelf life

3 years.
Do not use after the expiration date printed on the package.

Vacation conditions

Without recipe.