caffeine, paracetamol | Solpadein Fast soluble tablets 8 pcs.

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Briefly about the product

Solpadein Fast in a soluble form has an analgesic effect for migraine, headache, toothache and periodic pain. *

Solpadein Fast - directed action against pain!

* Medical Use Instructions, RU No Рџ N 014417/01 dated 11/18/2008
Briefly about the product

Solpadein Fast in a soluble form has an analgesic effect for migraine, headache, toothache and periodic pain. *

Solpadein Fast - directed action against pain!

* Medical Use Instructions, RU No Рџ N 014417/01 dated 11/18/2008

Description

Soluble white tablets, flat, with a circumferentially cut edge and a notch on one side.

Latin name

Solpadeine

Release form

Soluble tablets.

Pharmacological action

Combined analgesic-antipyretic, contains a combination of two active ingredients: paracetamol and caffeine. It has an antipyretic and analgesic effect.

Paracetamol blocks COX in the central nervous system, affecting the centers of pain and thermoregulation (in inflamed tissues, cellular peroxidases neutralize the effect of paracetamol on COX), which explains the almost complete absence of anti-inflammatory effect.

The absence of influence on the synthesis of prostaglandins in peripheral tissues leads to the absence of a negative effect on water-salt metabolism (sodium and water retention) and gastrointestinal mucosa.

Caffeine stimulates the psychomotor centers of the brain, has an analeptic effect, enhances the effect of analgesics, eliminates drowsiness and a feeling of fatigue, increases physical and mental performance.

Indications

Headache

migraine

toothache

back pain

neuralgia

muscle and rheumatic pain

painful menstruation

sore throat

symptomatic treatment for colds and flu (symptomatic treatment for colds.

Contraindications

Severe liver dysfunction

severe renal dysfunction

arterial hypertension

glaucoma

sleep disturbance

epilepsy

children under 12 years of age

hypersensitivity to the components of the drug.

Caution is advised to use the drug for benign hyperbilirubinemia (including Gilbert syndrome), viral hepatitis, alcoholic liver damage, glucose-6-phosphate dehydrogenase deficiency, alcoholism.

Use during pregnancy and lactation

The drug Solpadein Fast contains caffeine. When taking caffeine there is a high risk of having a baby with a low body weight, the risk of spontaneous abortion.

Once in breast milk, caffeine can have a stimulating effect on a breast-fed baby.

Solpadein Fast should not be used during pregnancy and lactation (breastfeeding).

Special instructions

If there is no improvement in the condition when taking the drug or if the headache becomes constant, consult a doctor.

While taking the drug, it is not recommended that you consume excess caffeinated foods (including tea, coffee), because this can lead to anxiety, anxiety, irritability, insomnia, headache, disorders of the gastrointestinal tract, tachycardia, cardiac arrhythmia.

In cases of prolonged use in high doses, monitoring of the blood picture is necessary.

Glutathione deficiency due to eating disorders, cystic fibrosis, HIV infection, starvation, and malnutrition makes it possible to develop severe liver damage with small overdoses of paracetamol (5 g or more).

The drug should not be taken concomitantly with other paracetamol-containing drugs.

In order to avoid toxic liver damage, paracetamol should not be combined with alcoholic beverages, and should also be taken by people prone to chronic alcohol consumption.

Patients with atopic bronchial asthma, hay fever, have an increased risk of allergic reactions.

In patients with renal and insufficiency, the drug should be used with caution and only after consulting a doctor.

When taking the drug in patients with non-alcoholic liver cirrhosis, there is a high risk of overdose.

When conducting tests to determine uric acid and blood glucose, you should tell your doctor about taking the drug.

Against the background of taking the drug, it is possible to change the results of doping control analyzes of athletes.

Composition

Active ingredients:

paracetamol 500 mg

caffeine 65 mg.

Excipients:

pregelatinized starch 50 mg,

corn starch 41.4 mg,

povidone 2 mg,

potassium sorbate 0.6 mg,

talcum 15 mg,

stearic acid 5 mg,

croscarmellose sodium 10 mg,

hypromellose 5 mg,

triacetin 1 mg.

Dosage and administration

Soluble tablets Solpadein Fast before oral administration should be dissolved in at least 100 ml(half a glass) of water.

Adults (including the elderly) and children over 12 years of age are prescribed 1-2 tablets. 3-4 times / day, if necessary. The interval between doses is at least 4 hours. The maximum single dose is 2 tablets, the maximum daily dose is 8 tablets.

The drug is not recommended for more than five days as an anesthetic and more than three days as an antipyretic without prescribing and monitoring a doctor.

An increase in the daily dose of the drug or the duration of treatment is possible only under the supervision of a doctor.

Side effects

The recommended doses are usually well tolerated.

Determination of frequency of side effects: very common ( 1/10), often ( 1/100 and <1/10), infrequent ( 1/1000 and <1/100), rare ( 1/10 000 and < 1/1000), very rare ( 1/100 000 and <1/10 000).

The following side effects have been identified spontaneously during post-registration administration of the drug.

Paracetamol

Allergic reactions: very rare - skin rash, angioedema (Quincke's edema), Stevens-Johnson syndrome, anaphylaxis.

From the hematopoietic system: very rarely - leukopenia, thrombocytopenia, methemoglobinemia, agranulocytosis, hemolytic anemia.

From the respiratory system: very rarely - bronchospasm (in patients with hypersensitivity to acetylsalicylic acid and NSAIDs).

From the hepatobiliary system: very rarely - impaired liver function.

Prolonged use at high doses increases the likelihood of hepatotoxic action, nephrotoxicity, and pancytopenia. Also, in cases of prolonged use in high doses, blood picture control is required.

Caffeine

Possible: dyspeptic phenomena (including nausea, epigastric pain), increased excitability, dizziness, sleep disorders, tachycardia.

In case of excessive consumption of caffeinated food (including tea, coffee) while taking the drug may cause anxiety, anxiety, irritability, insomnia, headache, disorders of the digestive system, tachycardia, cardiac arrhythmia.

If any of these side effects occur, you should stop taking the medication and consult your doctor immediately.

Drug Interaction

With regular administration for a long time, the drug increases the effect of indirect anticoagulants (warfarin and other coumarins), which increases the risk of bleeding. Episodic intake of a single dose of the drug has no significant effect on the effect of indirect anticoagulants.

The drug enhances the action of MAO inhibitors.

Barbiturates, carbamazepine, phenytoin, primidone, ethanol, rifampicin, phenylbutazone, St. John's wort, tricyclic antidepressants and other inducers of microsomal oxidation increase the production of hydroxylated active metabolites, causing the possibility of the development of peroxidation.

Microsomal oxidation inhibitors (cimetidine) reduce the risk of hepatotoxic action.

Under the influence of paracetamol, the elimination time of chloramphenicol is increased 5-fold.

Caffeine accelerates the absorption of ergotamine.

Concurrent administration of paracetamol and alcoholic beverages increases the risk of hepatotoxic effects and acute pancreatitis.

Metoclopramide and domperidone increase, and cholestyramine reduces the absorption rate of paracetamol.

The drug may reduce the effectiveness of uricosuric drugs.

Storage Conditions

Keep out of the reach and sight of children at temperatures not exceeding 25 РC.

Expiration

4 years.

Pharmacy vacation terms

Pharmacy terms

Pharmacy

Famar S.A., Greece

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