Bifidumbacterin powder for oral administration and topical application 5 doses., No. 10 pack .

For oral administration:

• prevention and treatment of gastrointestinal dysbiosis of various etiologies (including gastric ulcer and duodenal ulcer, pancreatitis, cholecystitis, hepatitis, allergic diseases, prescribing antimicrobial drugs, hormones and NSAIDs);

• acute intestinal infections (shigellosis, salmonellosis, staphylococcal enterocolitis, rotavirus infection), foodborne infection, malabsorption syndrome, chronic constipation or diarrhea against the background of prolonged antibiotic therapy;

• correction of microbiocenosis before and after operations on the intestines, liver, pancreas;

• prevention of nosocomial infection and dysbiosis in patients who often suffer from ARVI.

For local, intravaginal and rectal administration:

• dysbiosis of the urogenital tract, acute and chronic inflammatory diseases of the urogenital tract (including urogenital infections, sexually transmitted infections - gonorrhea, urogenital chlamydia, genital herpes);

• bacterial vaginosis (gardnerellosis);

• nonspecific colpitis (including hormone-dependent colpitis - senile);

• chronic colitis of various etiologies, intestinal dysfunction after acute intestinal infection;

• preparation for planned gynecological operations (for the prevention of postoperative infectious complications);

• prenatal preparation of pregnant women at risk of inflammatory diseases (for the prevention and treatment of vaginal dysbiosis).

Dosage regimen

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Administered orally, topically, intravaginally, rectally.

The dose and treatment regimen are set individually, depending on age, indications, and the dosage form used.

Side effect

Possibly: allergic reactions, nausea.

Contraindications for use

Individual intolerance.

special instructions

The simultaneous use of oral forms with antibiotics is not recommended, as well as dissolution of the drug in hot water (above 40 ?) and storage in a dissolved form.

The use of suppositories can be combined with the simultaneous administration of antibacterial, antiviral and immunostimulating drugs.

Drug interactions

The effect of preparations containing bifidobacteria bifidum is enhanced by vitamins (especially of group B), and antibiotics are reduced.

Inside, during meals (mixed with the liquid part of food, preferably fermented milk, or with 30-50 ml of boiled water at room temperature, or with breast milk)

for the prevention of intestinal diseases for adults and children from 3 years old - 2 sachets 1-2 times a day, children over 6 months - 1 sachet 1-2 times a day, up to 6 months - 1 sachet once a day, during 2-3 weeks 2-3 times a year.

Treatment: adults and children over 7 years old - 2 sachets 3-4 times a day; children 3-7 years old - 1 sachet 3-5 times a day, from 6 months to 3 years old - 1 sachet 3-4 times a day, up to 6 months - 1 sachet 2-3 times a day, if necessary, from 2-3 days to 4-6 times a day.

The course is 3-4 weeks, again - in a month.

Acute intestinal infections: in therapeutic doses for 5-7 days.

Outwardly, for the prevention of mastitis: 20-30 minutes before feeding with a sterile swab dipped in a solution of the drug (1 sachet is dissolved in 10-15 ml of boiled water at room temperature), the nipples and areola of the mammary glands are treated for 5 days.

In gynecology: a tampon is injected intravaginally, abundantly moistened in a solution of the drug (the contents of 2 sachets are dissolved in 15Ц20 ml of boiled water at room temperature) for 2-3 hours.

The course is 8-10 days.

Active substance: bifidumbacteria - not less than 500 million (5-108) CFU.

Excipient: lactose monohydrate - up to 0.85 g.

Individual intolerance.

Clinical and pharmacological group: A drug that regulates the balance of intestinal microflora (probiotic)

Pharmaco-therapeutic group: MIBP-eubiotic

pharmachologic effect

Live bifidobacteria possess high antagonistic activity against a wide range of pathogenic and opportunistic intestinal microorganisms (including staphylococci, Proteus, enteropathogenic E. coli, Shigella, some yeast-like fungi), restore the balance of intestinal and vaginal microflora, and normalize the functions of the digestive system , increase the nonspecific resistance of the organism.

Indications

For oral administration:

• prevention and treatment of gastrointestinal dysbiosis of various etiologies (including gastric ulcer and duodenal ulcer, pancreatitis, cholecystitis, hepatitis, allergic diseases, prescribing antimicrobial drugs, hormones and NSAIDs);

• acute intestinal infections (shigellosis, salmonellosis, staphylococcal enterocolitis, rotavirus infection), foodborne infection, malabsorption syndrome, chronic constipation or diarrhea against the background of prolonged antibiotic therapy;

• correction of microbiocenosis before and after operations on the intestines, liver, pancreas;

• prevention of nosocomial infection and dysbiosis in patients who often suffer from ARVI.

For local, intravaginal and rectal administration:

• dysbiosis of the urogenital tract, acute and chronic inflammatory diseases of the urogenital tract (including urogenital infections, sexually transmitted infections - gonorrhea, urogenital chlamydia, genital herpes);

• bacterial vaginosis (gardnerellosis);

• nonspecific colpitis (including hormone-dependent colpitis - senile);

• chronic colitis of various etiologies, intestinal dysfunction after acute intestinal infection;

• preparation for planned gynecological operations (for the prevention of postoperative infectious complications);

• prenatal preparation of pregnant women at risk of inflammatory diseases (for the prevention and treatment of vaginal dysbiosis).

Method of administration and dosage:

Inside, during meals (mixed with the liquid part of food, preferably fermented milk, or with 30-50 ml of boiled water at room temperature, or with breast milk)

for the prevention of intestinal diseases for adults and children from 3 years old - 2 sachets 1-2 times a day, children over 6 months - 1 sachet 1-2 times a day, up to 6 months - 1 sachet once a day, during 2-3 weeks 2-3 times a year.

Treatment: adults and children over 7 years old - 2 sachets 3-4 times a day; children 3-7 years old - 1 sachet 3-5 times a day, from 6 months to 3 years old - 1 sachet 3-4 times a day, up to 6 months - 1 sachet 2-3 times a day, if necessary, from 2-3 days to 4-6 times a day.

The course is 3-4 weeks, again - in a month.

Acute intestinal infections: in therapeutic doses for 5-7 days.

Outwardly, for the prevention of mastitis: 20-30 minutes before feeding with a sterile swab dipped in a solution of the drug (1 sachet is dissolved in 10-15 ml of boiled water at room temperature), the nipples and areola of the mammary glands are treated for 5 days.

In gynecology: a tampon is injected intravaginally, abundantly moistened in a solution of the drug (the contents of 2 sachets are dissolved in 15Ц20 ml of boiled water at room temperature) for 2-3 hours.

The course is 8-10 days.

Application during pregnancy and lactation

The drug is approved for use by women during pregnancy and breastfeeding.

There are no special conditions for admission.

Contraindications

Hypersensitivity.

Side effects

Allergic reactions are possible.

Interaction

There are no undesirable effects when interacting with other drugs.

The drug can be used in combination with antibacterial drugs.

The effect is enhanced by vitamins (especially of group B), reduced by antibiotics.

Overdose

An overdose of the drug Bifidumbacterin is impossible due to the lack of cumulative action.

Special instructions

The drug should not be used if the integrity of the individual packaging is violated, labeling is violated.

To dilute the drug, do not use water with a temperature above 40C and do not store bifidumbacterin in a diluted form.

Release form

Powder for oral and topical use.

Storage conditions

In a dry place, at a temperature not exceeding 10 ? C