Betaxolol | Xonef eye drops 0.5%, 5 ml
Special Price
$18.43
Regular Price
$27.00
In stock
SKU
BID470666
Latin name
Xonef
Xonef
Latin name
Xonef
Packaging
5 ml - plastic dropper bottle (1) - packs of cardboard.
Pharmacological action of
Anti-glaucoma drug. Selective beta1-blocker without internal sympathomimetic activity. It does not have a membrane stabilizing (local anesthetic) effect.
Topical application of betaxolol reduces intraocular pressure by reducing the production of intraocular fluid.
The onset of the hypotensive effect is observed 30 minutes after instillation, the maximum effect develops after 2 hours. After a single instillation, the effect on ophthalmotonus persists for 12 hours.
Betaxolol (compared with other beta-blockers) does not cause a decrease in blood flow in the optic nerve.
The use of Xonef eye drops does not lead to the appearance of miosis, accommodation spasm, hemeralopia (unlike myotics).
Indications
As monotherapy: to reduce intraocular pressure.
In combination with other drugs for: open-angle glaucoma
ocular hypertension.
Contraindications
sinus bradycardia
AV block II and III degree
severe heart failure
cardiogenic shock
arterial hypotension
children under 18 years of age
hypersensitivity to the components of the drug.
With caution, the drug should be used for thyrotoxicosis, myasthenia gravis, diabetes mellitus, Raynaud's syndrome, pheochromocytoma, bronchial asthma, chronic obstructive bronchitis.
Use during pregnancy and lactation
There is no sufficient experience with the use of Xonef during pregnancy and lactation.
The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the intended benefit to the mother outweighs the potential risk to the fetus or child.
Composition
1 ml contains
Active ingredient: betaxolol 5 mg
Excipients: benzalkonium chloride, hypromellose, sodium chloride, sodium hydroxide, disodium edetate, water d / i.
Dosage and administration
The drug is instilled in the conjunctival sac, 1-2 drops 2 times / day.
In some patients, stabilization of intraocular pressure occurs within a few weeks, therefore it is recommended to control intraocular pressure during the first month of treatment.
With insufficient clinical efficacy of monotherapy, additional therapy is prescribed.
Side effects
From the side of the organ of vision: often - short-term discomfort in the eyes after instillation, lacrimation in some cases - decreased sensitivity of the cornea, redness of the eyes, acne keratitis, photophobia, anisocoria, photophobia, itching, dry eyes, allergic reactions.
Systemic side effects are rare:
From the central nervous system: dizziness, nausea, drowsiness, insomnia, headache, depression, increased symptoms of myasthenia gravis.
From the cardiovascular system: bradycardia, impaired cardiac conduction and heart failure.
From the respiratory system: dyspnea, bronchospasm, bronchial asthma, respiratory failure.
Drug Interaction
The simultaneous use of Xonef and beta-blockers for oral administration increases the risk of side effects (both local and systemic) due to the additive effect (therefore, patients receiving this combination of drugs should be monitored.
When using the drug Xonef in combination with drugs that deplete catecholamines (such as reserpine), a decrease in blood pressure and bradycardia can be observed.
When both muscle relaxants and hypoglycemic agents are given, their effects may increase.
When used with sympathomimetics, it enhances their vasoconstrictor effect.
Caution should be exercised when co-administering the drug Xonef with psychotropic agents as a result of their potentiation.
Overdose
In case of contact with excess drug, rinse eyes with warm water.
Symptoms: A decrease in blood pressure, bradycardia, acute heart failure may occur with an overdose of beta1-blockers.
Treatment: carry out symptomatic therapy.
Storage conditions
Store in a dry, dark place, out of the reach of children, at a temperature not exceeding 30 РC.
The Expiration of
is 3 years, after the bottle is opened - 45 days.
Deystvuyuschee substances
Betaxolol
dosage form
dosage form
eye drops
Sentiss Farm Pvt.Ltd, India
Xonef
Packaging
5 ml - plastic dropper bottle (1) - packs of cardboard.
Pharmacological action of
Anti-glaucoma drug. Selective beta1-blocker without internal sympathomimetic activity. It does not have a membrane stabilizing (local anesthetic) effect.
Topical application of betaxolol reduces intraocular pressure by reducing the production of intraocular fluid.
The onset of the hypotensive effect is observed 30 minutes after instillation, the maximum effect develops after 2 hours. After a single instillation, the effect on ophthalmotonus persists for 12 hours.
Betaxolol (compared with other beta-blockers) does not cause a decrease in blood flow in the optic nerve.
The use of Xonef eye drops does not lead to the appearance of miosis, accommodation spasm, hemeralopia (unlike myotics).
Indications
As monotherapy: to reduce intraocular pressure.
In combination with other drugs for: open-angle glaucoma
ocular hypertension.
Contraindications
sinus bradycardia
AV block II and III degree
severe heart failure
cardiogenic shock
arterial hypotension
children under 18 years of age
hypersensitivity to the components of the drug.
With caution, the drug should be used for thyrotoxicosis, myasthenia gravis, diabetes mellitus, Raynaud's syndrome, pheochromocytoma, bronchial asthma, chronic obstructive bronchitis.
Use during pregnancy and lactation
There is no sufficient experience with the use of Xonef during pregnancy and lactation.
The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the intended benefit to the mother outweighs the potential risk to the fetus or child.
Composition
1 ml contains
Active ingredient: betaxolol 5 mg
Excipients: benzalkonium chloride, hypromellose, sodium chloride, sodium hydroxide, disodium edetate, water d / i.
Dosage and administration
The drug is instilled in the conjunctival sac, 1-2 drops 2 times / day.
In some patients, stabilization of intraocular pressure occurs within a few weeks, therefore it is recommended to control intraocular pressure during the first month of treatment.
With insufficient clinical efficacy of monotherapy, additional therapy is prescribed.
Side effects
From the side of the organ of vision: often - short-term discomfort in the eyes after instillation, lacrimation in some cases - decreased sensitivity of the cornea, redness of the eyes, acne keratitis, photophobia, anisocoria, photophobia, itching, dry eyes, allergic reactions.
Systemic side effects are rare:
From the central nervous system: dizziness, nausea, drowsiness, insomnia, headache, depression, increased symptoms of myasthenia gravis.
From the cardiovascular system: bradycardia, impaired cardiac conduction and heart failure.
From the respiratory system: dyspnea, bronchospasm, bronchial asthma, respiratory failure.
Drug Interaction
The simultaneous use of Xonef and beta-blockers for oral administration increases the risk of side effects (both local and systemic) due to the additive effect (therefore, patients receiving this combination of drugs should be monitored.
When using the drug Xonef in combination with drugs that deplete catecholamines (such as reserpine), a decrease in blood pressure and bradycardia can be observed.
When both muscle relaxants and hypoglycemic agents are given, their effects may increase.
When used with sympathomimetics, it enhances their vasoconstrictor effect.
Caution should be exercised when co-administering the drug Xonef with psychotropic agents as a result of their potentiation.
Overdose
In case of contact with excess drug, rinse eyes with warm water.
Symptoms: A decrease in blood pressure, bradycardia, acute heart failure may occur with an overdose of beta1-blockers.
Treatment: carry out symptomatic therapy.
Storage conditions
Store in a dry, dark place, out of the reach of children, at a temperature not exceeding 30 РC.
The Expiration of
is 3 years, after the bottle is opened - 45 days.
Deystvuyuschee substances
Betaxolol
dosage form
dosage form
eye drops
Sentiss Farm Pvt.Ltd, India
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