Berocca plus effervescent tablets, No. 30

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BIDL3178251
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Expiration Date: 11/2025

Russian Pharmacy name:

Берокка плюс таблетки шипучие, №30

Berocca plus effervescent tablets, No. 30

  • Deficiency and conditions accompanied by an increased need for B vitamins, vitamin C and zinc.

The content of vitamins in BeroccaЃ Plus is selected for therapeutic use in conditions accompanied by a deficiency or an increase in the need for vitamins:

  • increased physical activity, a period of prolonged nervous tension and stress;

  • inadequate and unbalanced nutrition (restrictive diets);

  • in the elderly (effervescent tablets);

  • chronic alcoholism;

  • nicotine addiction (in smokers) (effervescent tablets), as well as the use of oral contraceptives in women) (effervescent tablets).

Effervescent tablets are pre-dissolved in a glass of water.

Adults and children from 15 years old: 1 tab. in a day.

Do not exceed the recommended daily dose of the drug.

The recommended course duration is 30 days.

Repeated courses - on the recommendation of a doctor

Effervescent Tablets Valium, from pale orange to light orange color, interspersed with darker and lighter colors; dissolve in water with the release of bubbles, forming an orange-scented solution.

1 tab.

ascorbic acid (vit. C) - 500 mg

thiamine hydrochloride (vit. B1) 1-15 mg

riboflavin (vit. B2) 2 - 15 mg

nicotinamide (vit. B3) - 50 mg

pantothenic acid (vit. B5) 3 - 23 mg

pyridoxine hydrochloride (vit. B6) - 10 mg

biotin (vit. B8) - 150 mcg

folic acid (vit. B9) - 400 mcg

cyanocobalamin (vit. B12) 4 - 10 ?g

calcium (in the form of calcium carbonate and calcium pantothenate) 5 - 100 mg

magnesium (in the form of heavy magnesium carbonate and magnesium sulfate dihydrate) 6 - 100 mg

zinc (in the form of zinc trihydrate) 7-10 mg

Excipients: citric acid anhydrous - 1700 mg, sodium bicarbonate - 840 mg, sodium carbonate anhydrous - 60 mg, sodium chloride - 40 mg, acesulfame potassium - 20 mg, aspartame - 25 mg, beetroot red (E162) - 30 mg, beta -carotene (E160a) - 40 mg, orange flavor - 100 mg, polysorbate 60 - 900 mcg, mannitol - 16.848 mg, isomalt - 265.531 mg, sorbitol - 155.3027 mg.

  • hypercalcemia;

  • hypermagnesemia;

  • urolithiasis (nephrolithiasis, urolithiasis);

  • hemochromatosis;

  • hyperoxaluria;

  • impaired renal function;

  • deficiency of glucose-6-phosphate dehydrogenase;

  • intolerance to fructose (for effervescent tablets);

  • children under 15 years of age;

  • hypersensitivity to the components of the drug.

Care should be taken to prescribe the drug to patients with atrophic gastritis, bowel disease, pancreas, vitamin B12 deficiency syndrome or congenital Castle's intrinsic factor deficiency.

pharmachologic effect

Combined drug, the pharmacological action of which is due to the vitamins and microelements included in its composition.

B vitamins are involved in many metabolic reactions, incl. synthesis of neurotransmitters.

Vitamin C (ascorbic acid) is a biological antioxidant and plays an important role in the inactivation of free radicals, increases the absorption of iron in the small intestine, affects the metabolism of folic acid and the function of leukocytes. Stimulates the formation of connective tissue, bone tissue, normalizes capillary permeability.

Calcium takes part in many physiological processes, the functioning of enzyme systems, the transmission of nerve impulses in combination with magnesium and vitamin B6.

Magnesium is involved in various reactions, including protein synthesis, fatty acid metabolism, and sugar oxidation.

Zinc as a catalyst activates more than 200 enzymes and is a component of many proteins, hormones, neuropeptides, hormonal receptors, and is also directly involved in the synthesis of coenzymes, pyridoxine derivatives.

Water-soluble vitamins do not accumulate in the body, therefore, in conditions accompanied by an increased need for vitamins and minerals, the amount of vitamins supplied with food may be insufficient.

Pharmacokinetics

Data on the pharmacokinetics of BeroccaЃ Plus are not provided.

Indications for BeroccaЃ Plus

  • Deficiency and conditions accompanied by an increased need for B vitamins, vitamin C and zinc.

The content of vitamins in BeroccaЃ Plus is selected for therapeutic use in conditions accompanied by a deficiency or an increase in the need for vitamins:

  • increased physical activity, a period of prolonged nervous tension and stress;

  • inadequate and unbalanced nutrition (restrictive diets);

  • in the elderly (effervescent tablets);

  • chronic alcoholism;

  • nicotine addiction (in smokers) (effervescent tablets), as well as the use of oral contraceptives in women) (effervescent tablets).

Dosage regimen

The drug is taken orally.

An effervescent tablet is preliminarily dissolved in a glass of water.

Adults and children aged 15 years and older are prescribed 1 tablet / day.

Do not exceed the recommended daily dose of the drug.

The recommended duration of the course of treatment is 30 days.

The doctor determines the need for a second course of treatment individually.

Side effect

On the part of the digestive system: mild transient gastrointestinal disorders are possible.

Allergic reactions: rarely ( <1/10 000) - urticaria, rash, laryngeal edema, anaphylactic shock.

From the hematopoietic system: in patients with glucose-6-phosphate dehydrogenase deficiency, ascorbic acid can cause hemolytic anemia.

From the nervous system: headache, dizziness, insomnia, irritability.

Contraindications for use

  • hypercalcemia;

  • hypermagnesemia;

  • urolithiasis (nephrolithiasis, urolithiasis);

  • hemochromatosis;

  • hyperoxaluria;

  • impaired renal function;

  • deficiency of glucose-6-phosphate dehydrogenase;

  • intolerance to fructose (for effervescent tablets);

  • children under 15 years of age;

  • hypersensitivity to the components of the drug.

Care should be taken to prescribe the drug to patients with atrophic gastritis, bowel disease, pancreas, vitamin B12 deficiency syndrome or congenital Castle's intrinsic factor deficiency.

Application during pregnancy and lactation

BeroccaЃ Plus is not intended for use in pregnant or lactating women.

Vitamins and minerals in dosages used in dietary supplements are generally considered safe for use during pregnancy and lactation. However, BeroccaЃ Plus should be used during pregnancy strictly for medical reasons.

The vitamins and minerals contained in BeroccaЃ Plus are excreted in breast milk. There are no data on the safety of the drug when used during lactation.

Application for impaired renal function

The drug is contraindicated for use in case of impaired renal function, urolithiasis (nephrolithiasis, urolithiasis).

Application in children

The use of the drug in children under 15 years of age is contraindicated.

Use in elderly patients

The drug is approved for use in elderly patients.

special instructions

Ascorbic acid can interfere with urine glucose test results, although it does not affect blood glucose levels. Vitamin C should be discontinued a few days before these tests are performed.

It is possible that urine is stained yellow, which has no clinical significance and is explained by the presence of riboflavin in the preparation.

The product does not contain fat-soluble vitamins.

1 tablet contains the maximum daily dose of pyridoxine, therefore, the recommended dose of the drug should not be exceeded.

1 tablet contains 12.5% ??of the RDA for calcium and 33.3% of the RDA for magnesium. However, for the treatment of calcium and magnesium deficiency, taking only BeroccaЃ Plus is not sufficient.

1 effervescent tablet contains 272 mg of sodium, therefore patients on a diet with limited salt intake are advised to take BeroccaЃ Plus in the form of film-coated tablets.

If you have an intolerance to some sugars, the patient should consult a doctor before taking the drug.

Patients taking other medicines should consult a doctor before taking BeroccaЃ Plus.

Information for patients with diabetes mellitus

1 effervescent tablet contains 276 mg of mannitol, which corresponds to 0.028 XE and an energy value of 0.66 kcal, 1 film-coated tablet contains 25 mg of mannitol, 94 mg of lactose monohydrate and 13.44 mg of dextrose, which corresponds to 0.02 XE and an energy value of 0.143 kcal , therefore, the drug can be taken by patients with diabetes mellitus.

Influence on the ability to drive vehicles and use mechanisms

BeroccaЃ Plus does not affect the ability to drive vehicles and control moving machinery.

Overdose

No cases of overdose have been reported.

Symptoms: Possible gastrointestinal disturbances such as diarrhea and stomach discomfort. Excessive intake of vitamin B6 (more than 20 tablets / day and for several months) can lead to symptoms of neuropathy.

Treatment: the patient should stop taking the drug and consult a doctor.

Drug interactions

Pyridoxine at a dose exceeding 5 mg can neutralize the effect of levodopa in patients with parkinsonism. However, this antagonism is not observed when levodopa is used in combination with a decarboxylase inhibitor (eg, benserazide, cardbidopa).

Thiosemicarbazone and 5-fluorouracil neutralize the effect of thiamine.

Antacids inhibit thiamine resorption.

Neomycin, aminosalicylic acid and histamine H2 receptor blockers reduce the absorption of cyanocobalamin.

Acetylsalicylic acid reduces the absorption of ascorbic acid by about a third.

Oral contraceptives can reduce serum levels of cyanocobalamin, folic acid, pyridoxine, ascorbic acid.

In some patients taking daily deferoxamine and ascorbic acid at a dose of 500 mg, transient left ventricular dysfunction may occur.

Storage conditions of the drug BeroccaЃ Plus

Effervescent tablets should be stored in tightly closed packaging, out of the reach of children at a temperature not exceeding 25 ? C.

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