Benatex vaginal suppositories 18.9mg, No. 10

Local contraception for women of reproductive age:

• if there are contraindications to the use of oral contraceptives or intrauterine contraception;

• in the postpartum period;

• during lactation;

• in the period after the termination of pregnancy;

• in the premenopausal period;

• if necessary, occasional protection from pregnancy;

• if you miss or are late in taking constantly used oral contraceptives.

Having previously released the suppository from the contour packaging, it is inserted deep into the vagina in the supine position 5 minutes before intercourse.

Single dose: 1 suppository is designed for 1 sexual intercourse. The duration of action of the drug is 4 hours.

It is imperative to introduce a new vaginal suppository with repeated intercourse. The frequency of use is limited by the individual tolerance of the active substance and the frequency of sexual intercourse.

Active ingredient: myristalconium chloride (benzalkonium chloride C14) - 18.9 mg

Excipients: solid fat (Witepsol (grades H 15, W 35), Supposir (grades NA 15, NAS 50)) - until a suppository weighing 1.75 g is obtained.

• colpitis;

• ulceration and irritation of the lining of the uterus and vagina;

• hypersensitivity to the components of the drug.

Clinical and pharmacological group: Vaginal contraceptive with spermicidal action

Pharmaco-therapeutic group: Contraceptive for topical use

pharmachologic effect

Contraceptive preparation for topical use. It has a spermicidal effect, as well as antiseptic, antifungal, antiprotozoal action, inactivates the Herpes simplex virus.

The drug is active against gram-positive bacteria (including Staphylococcus spp., Streptococcus spp.); gram-negative bacteria (including Escherichia coli, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Proteus spp., Klebsiella spp.); anaerobic bacteria, fungi and molds .

Also active against bacterial strains resistant to antibiotics and other chemotherapeutic drugs; inhibits plasmacoagulase and hyaluronidase of staphylococci.

The spermatocidal effect of the drug is due to the ability to damage the membranes of spermatozoa (at the beginning of the flagella, then the head), which makes it impossible to fertilize the egg with a damaged sperm. The effect develops 5 minutes after the introduction of the vaginal suppository.

Shows activity in the prevention of sexually transmitted diseases (including gonorrhea, chlamydia, trichomoniasis). Does not affect the normal microflora of the vagina (including Dederlein's bacillus) and the hormonal cycle.

Pharmacokinetics

The drug is practically not absorbed after intravaginal administration, it is removed by simple washing with water and with normal physiological secretions.

Indications

Local contraception for women of reproductive age:

• if there are contraindications to the use of oral contraceptives or intrauterine contraception;

• in the postpartum period;

• during lactation;

• in the period after the termination of pregnancy;

• in the premenopausal period;

• if necessary, occasional protection from pregnancy;

• if you miss or are late in taking constantly used oral contraceptives.

Dosage regimen

Having previously released the suppository from the contour packaging, it is inserted deep into the vagina in the supine position 5 minutes before intercourse.

Single dose: 1 suppository is designed for 1 sexual intercourse. The duration of action of the drug is 4 hours.

It is imperative to introduce a new vaginal suppository with repeated intercourse. The frequency of use is limited by the individual tolerance of the active substance and the frequency of sexual intercourse.

Side effect

Possibly: allergic reactions.

Contraindications for use

• colpitis;

• ulceration and irritation of the lining of the uterus and vagina;

• hypersensitivity to the components of the drug.

Application during pregnancy and lactation

The drug has no harmful effect on the course of pregnancy.

The drug can be used during breastfeeding, since it is not excreted in breast milk.

special instructions

To increase the effectiveness, careful adherence to the method of application of the drug is necessary.

It can be used in conjunction with a vaginal diaphragm or intrauterine contraception.

After intercourse, intravaginal use of hygiene products (douching with soapy water, since soap destroys the active substance of the drug) is not recommended in order to avoid loss of the contraceptive effect; an external genital toilet is possible.

Overdose

Data on drug overdose are not provided.

Drug interactions

Any drug administered intravaginally can reduce the local spermicidal effect (including soap and solutions containing it).

Iodine solutions (including 0.1% iodonate solution) inactivate the drug.

Storage conditions

The drug should be stored out of the reach of children, in a dry, dark place at a temperature not exceeding 20 ? C.

Shelf life

Shelf life is 2 years.

Terms of sale

The drug is approved for use as a means of OTC.

Contacts for inquiries

STADA (Russia)