Bacteriophage Pseudomonas aeruginosa | Bacteriophage pseudomonas solution for oral, local and external use of fl. 100 ml
Special Price
$27.60
Regular Price
$39.00
In stock
SKU
BID475103
Release form
Solution.
Solution.
Release form
Solution.
Packaging
In a bottle of 100 ml of solution. In the package 1 bottle.
Pharmacological action
Antibacterial specific effect.
Pharmacodynamics and pharmacokinetics
Pseudomonas aeruginosa bacteriophage has the ability to selectively destroy Pseudomonas aeruginosa microorganisms.
The bactericidal effect of bacteriophages is caused by the specific lysis of pathogenic bacteria in the inflammatory focus. The death of bacteria occurs due to the adsorption of virulent bacteriophages on the surface of the microbe cell, penetration into it and intensive reproduction, the use of cell organelles for their needs, after which the cell dies.
Pharmacokinetics not studied.
Indications
Diseases of the ear, throat, nose, respiratory tract and lungs:
Inflammation of the sinuses of the nose, middle ear.
tonsillitis.
pharyngitis.
Laryngitis.
Tracheitis.
Bronchitis.
Pneumonia.
Pleurisy.
Surgical infections:
Suppuration of wounds.
Burns.
abscess.
Phlegmon.
Boils.
Carbuncle.
Hydradenitis.
Panaritium.
Paraproctitis.
mastitis.
bursitis.
Osteomyelitis.
Urogenital infections:
Urethritis.
Cystitis.
Pyelonephritis.
Colpit.
Endometritis.
Salpingoophoritis.
Enteral infections:
Gastroenteritis.
Cholecystitis.
Dysbacteriosis of the intestine.
Generalized septic diseases.
Purulent-inflammatory diseases of the newborn:
Omphalitis.
Pyoderma.
Conjunctivitis.
Gastroenterocolitis.
sepsis.
Other diseases caused by Pseudomonas aeruginosa.
As a preventative measure:
Treatment of postoperative and freshly infected wounds.
Prevention of nosocomial infections according to epidemic indications.
Contraindications
None.
Use during pregnancy and lactation
The instruction does not prohibit the use of the drug in these periods, subject to monitoring by the attending physician.
Composition
Sterile filtrate of bacterial phagolysates of Pseudomonas aeroginosa.
Excipients: quinosol 0.0001 g / ml (preservative).
Dosage and administration
Shake and shake the vial with the bacteriophage before use. The drug should be transparent and not contain sediment.
Attention! In case of turbidity, do not use the drug!
Due to the presence in the preparation of a nutrient medium in which bacteria from the environment can develop, causing clouding of the drug, the following rules must be observed when opening the bottle:
Wash hands thoroughly.
Treat the cap with an alcohol-containing solution.
Remove the cap without opening the plug.
Do not place the cork with the inside on a table or other objects.
Do not leave vial open.
Store the opened bottle only in the refrigerator.
Opening the bottle and extracting the required volume of the drug can be carried out with a sterile syringe by piercing the cork.
The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the expiration date.
The drug is used for oral administration (by mouth), rectal administration, applications, irrigation, wound, vagina, uterus, nose, sinuses and drained cavities.
tab. Recommended dosages of the drug
Patient age Dose per 1 dose (ml)
Inside In an enema
0-6 months 5 5-10
6-12 months 10 10-20
Year to 3 years 15 20-30
3 to 8 years 15-20 30-40
From 8 years of age and older 20-30 40-50
Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by taking the drug inside for 7-20 days (according to clinical indications) .
If chemical antiseptics were used to treat wounds before the bacteriophage was used, the wound should be thoroughly washed with a sterile 0.9% sodium chloride solution.
Depending on the site of infection, the bacteriophage is used:
Application in the form of irrigation, lotions and plugging
It is carried out in a volume of up to 200 ml, depending on the size of the affected area.
With an abscess, after purulent contents have been removed by puncture, the drug is administered in an amount less than the volume of pus removed.
In osteomyelitis, after appropriate surgical treatment, a bacteriophage of 10-20 ml is poured into the wound.
Application by injection into the cavity
When introduced into the cavity (pleural, articular and other limited cavities) up to 100 ml, after which capillary drainage is left through which the bacteriophage is administered for several days.
Use for cystitis, pyelonephritis, urethritis
The drug is taken orally.
If the cavity of the bladder or renal pelvis is drained, the bacteriophage is injected through the cystostomy or nephrostoma 1-2 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis.
Application for purulent-inflammatory gynecological diseases
The drug is injected into the cavity of the vagina, uterus in a dose of 5-10 ml once daily.
Use for purulent-inflammatory diseases of the ear, throat, nose
The drug is administered in a dose of 2-10 ml 1-3 times a day. The bacteriophage is used to rinse, rinse, instill, administer moistened turundas (leaving them for 1 hour).
Use for enteric infections, intestinal dysbiosis
The drug is taken orally 3 times a day 1 hour before a meal. It is possible to combine a two-time oral administration with a single rectal administration of a single age-related dose of a bacteriophage in the form of an enema after bowel movement.
Use of a bacteriophage in children (up to 6 months)
Use in sepsis, enterocolitis in newborns, including premature babies
The bacteriophage is used in the form of high enemas (through a gas tube or catheter) 2-3 times a day at a dose of 5-10 ml.
In the absence of vomiting and regurgitation, it is possible to use the drug by mouth. In this case, it is mixed with breast milk.
A combination of rectal (in the form of high enemas) and oral (through the mouth) use of the drug is possible.
The course of treatment is 5-15 days. With a recurring course of the disease, repeated courses of treatment are possible. In order to prevent sepsis and enterocolitis during intrauterine infection or the risk of nosocomial infection in newborns, the bacteriophage is used as enemas 2 times a day for 5-7 days.
In the treatment of omphalitis, pyoderma, infected wounds
The drug is used in the form of applications twice daily (a gauze cloth is moistened with a bacteriophage and applied to the umbilical wound or affected area of the skin).
Side effects
Not found.
Drug Interactions
The drug can be combined with anti-inflammatory and antibacterial agents.
If antiseptics were used before treatment drugs were used, the wound should be washed with a solution of sodium chloride.
Overdose
No similar cases have been reported.
Storage Conditions
Store at 2 to 8 РC. Only store the opened vial in the refrigerator.
Keep out of the reach and sight of children.
Do not use after the expiry date.
Shelf life
2 years.
Terms and conditions
prescription
Dosage form
solution for oral administration
Prescribing
Prescribing
Pregnant as prescribed by a doctor, For adults as prescribed by a doctor, For children from birth, For children as prescribed by a doctor, Nursing mothers as prescribed by a doctor
Microgen NPO, Russia
Solution.
Packaging
In a bottle of 100 ml of solution. In the package 1 bottle.
Pharmacological action
Antibacterial specific effect.
Pharmacodynamics and pharmacokinetics
Pseudomonas aeruginosa bacteriophage has the ability to selectively destroy Pseudomonas aeruginosa microorganisms.
The bactericidal effect of bacteriophages is caused by the specific lysis of pathogenic bacteria in the inflammatory focus. The death of bacteria occurs due to the adsorption of virulent bacteriophages on the surface of the microbe cell, penetration into it and intensive reproduction, the use of cell organelles for their needs, after which the cell dies.
Pharmacokinetics not studied.
Indications
Diseases of the ear, throat, nose, respiratory tract and lungs:
Inflammation of the sinuses of the nose, middle ear.
tonsillitis.
pharyngitis.
Laryngitis.
Tracheitis.
Bronchitis.
Pneumonia.
Pleurisy.
Surgical infections:
Suppuration of wounds.
Burns.
abscess.
Phlegmon.
Boils.
Carbuncle.
Hydradenitis.
Panaritium.
Paraproctitis.
mastitis.
bursitis.
Osteomyelitis.
Urogenital infections:
Urethritis.
Cystitis.
Pyelonephritis.
Colpit.
Endometritis.
Salpingoophoritis.
Enteral infections:
Gastroenteritis.
Cholecystitis.
Dysbacteriosis of the intestine.
Generalized septic diseases.
Purulent-inflammatory diseases of the newborn:
Omphalitis.
Pyoderma.
Conjunctivitis.
Gastroenterocolitis.
sepsis.
Other diseases caused by Pseudomonas aeruginosa.
As a preventative measure:
Treatment of postoperative and freshly infected wounds.
Prevention of nosocomial infections according to epidemic indications.
Contraindications
None.
Use during pregnancy and lactation
The instruction does not prohibit the use of the drug in these periods, subject to monitoring by the attending physician.
Composition
Sterile filtrate of bacterial phagolysates of Pseudomonas aeroginosa.
Excipients: quinosol 0.0001 g / ml (preservative).
Dosage and administration
Shake and shake the vial with the bacteriophage before use. The drug should be transparent and not contain sediment.
Attention! In case of turbidity, do not use the drug!
Due to the presence in the preparation of a nutrient medium in which bacteria from the environment can develop, causing clouding of the drug, the following rules must be observed when opening the bottle:
Wash hands thoroughly.
Treat the cap with an alcohol-containing solution.
Remove the cap without opening the plug.
Do not place the cork with the inside on a table or other objects.
Do not leave vial open.
Store the opened bottle only in the refrigerator.
Opening the bottle and extracting the required volume of the drug can be carried out with a sterile syringe by piercing the cork.
The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the expiration date.
The drug is used for oral administration (by mouth), rectal administration, applications, irrigation, wound, vagina, uterus, nose, sinuses and drained cavities.
tab. Recommended dosages of the drug
Patient age Dose per 1 dose (ml)
Inside In an enema
0-6 months 5 5-10
6-12 months 10 10-20
Year to 3 years 15 20-30
3 to 8 years 15-20 30-40
From 8 years of age and older 20-30 40-50
Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by taking the drug inside for 7-20 days (according to clinical indications) .
If chemical antiseptics were used to treat wounds before the bacteriophage was used, the wound should be thoroughly washed with a sterile 0.9% sodium chloride solution.
Depending on the site of infection, the bacteriophage is used:
Application in the form of irrigation, lotions and plugging
It is carried out in a volume of up to 200 ml, depending on the size of the affected area.
With an abscess, after purulent contents have been removed by puncture, the drug is administered in an amount less than the volume of pus removed.
In osteomyelitis, after appropriate surgical treatment, a bacteriophage of 10-20 ml is poured into the wound.
Application by injection into the cavity
When introduced into the cavity (pleural, articular and other limited cavities) up to 100 ml, after which capillary drainage is left through which the bacteriophage is administered for several days.
Use for cystitis, pyelonephritis, urethritis
The drug is taken orally.
If the cavity of the bladder or renal pelvis is drained, the bacteriophage is injected through the cystostomy or nephrostoma 1-2 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis.
Application for purulent-inflammatory gynecological diseases
The drug is injected into the cavity of the vagina, uterus in a dose of 5-10 ml once daily.
Use for purulent-inflammatory diseases of the ear, throat, nose
The drug is administered in a dose of 2-10 ml 1-3 times a day. The bacteriophage is used to rinse, rinse, instill, administer moistened turundas (leaving them for 1 hour).
Use for enteric infections, intestinal dysbiosis
The drug is taken orally 3 times a day 1 hour before a meal. It is possible to combine a two-time oral administration with a single rectal administration of a single age-related dose of a bacteriophage in the form of an enema after bowel movement.
Use of a bacteriophage in children (up to 6 months)
Use in sepsis, enterocolitis in newborns, including premature babies
The bacteriophage is used in the form of high enemas (through a gas tube or catheter) 2-3 times a day at a dose of 5-10 ml.
In the absence of vomiting and regurgitation, it is possible to use the drug by mouth. In this case, it is mixed with breast milk.
A combination of rectal (in the form of high enemas) and oral (through the mouth) use of the drug is possible.
The course of treatment is 5-15 days. With a recurring course of the disease, repeated courses of treatment are possible. In order to prevent sepsis and enterocolitis during intrauterine infection or the risk of nosocomial infection in newborns, the bacteriophage is used as enemas 2 times a day for 5-7 days.
In the treatment of omphalitis, pyoderma, infected wounds
The drug is used in the form of applications twice daily (a gauze cloth is moistened with a bacteriophage and applied to the umbilical wound or affected area of the skin).
Side effects
Not found.
Drug Interactions
The drug can be combined with anti-inflammatory and antibacterial agents.
If antiseptics were used before treatment drugs were used, the wound should be washed with a solution of sodium chloride.
Overdose
No similar cases have been reported.
Storage Conditions
Store at 2 to 8 РC. Only store the opened vial in the refrigerator.
Keep out of the reach and sight of children.
Do not use after the expiry date.
Shelf life
2 years.
Terms and conditions
prescription
Dosage form
solution for oral administration
Prescribing
Prescribing
Pregnant as prescribed by a doctor, For adults as prescribed by a doctor, For children from birth, For children as prescribed by a doctor, Nursing mothers as prescribed by a doctor
Microgen NPO, Russia
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