bacteriophage Klebsiella | Bacteriophage Klebsiella polyvalent vials, 20 ml, 4 pcs.
Special Price
$28.52
Regular Price
$40.00
In stock
SKU
BID494527
Release form
Solution for oral administration, local and external use.
Solution for oral administration, local and external use.
Release form
Solution for oral administration, local and external use.
Packing
4 vials of 20 ml.
Pharmacological action of
The drug causes specific lysis of bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis.
Indications
Treatment and prevention of diseases caused by bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis as part of complex therapy: Ozen, scleroma.
Diseases of the gastrointestinal tract (gastroenterocolitis, cholecystitis, pancreatitis, intestinal dysbiosis).
Inflammatory diseases of newborns and young children (gastroenterocolitis, intestinal dysbiosis, omphalitis, pemphigus, pyoderma, septicemia and septicopyemia of various localization).
Surgical infections (suppuration of wounds, purulent skin lesions, burns, peritonitis, pleurisy, mastitis, osteomyelitis, abscess).
Urogenital infections (cystitis, pyelonephritis, urethritis, endometritis, vulvitis, bartholinitis, colpitis, salpingo-oophoritis).
Purulent-inflammatory diseases of the ear, throat, nose, sinuses, mouth, pharynx, larynx, bronchi, lungs and pleura (otitis media, tonsillitis, pharyngitis, laryngitis, stomatitis, periodontitis, sinusitis, frontal sinusitis, bronchitis, pneumonia, pleurisy).
Post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcer and iridocyclitis.
Prevention of nosocomial infections caused by Klebsiella.
An important condition for effective phage therapy is a preliminary determination of the phage sensitivity of the pathogen.
Contraindications
Hypersensitivity to the components of the drug.
Use during pregnancy and lactation
Use of this drug during pregnancy and during lactation is possible in the presence of infections caused by phage-sensitive strains of Klebsiella (as recommended by a doctor).
Special instructions
Shake and shake the vial with the bacteriophage before use. The drug should be transparent and not contain sediment.
Attention! In case of turbidity, do not use the drug!
Due to the presence in the preparation of a nutrient medium in which bacteria from the environment can develop, causing clouding of the drug, the following rules must be observed when opening the bottle: Wash hands thoroughly.
Treat the cap with an alcohol-containing solution.
Remove the cap without opening the plug.
Do not place the cork with the inner surface on a table or other objects.
Do not leave vial open.
Store the opened bottle only in the refrigerator.
When using small doses (2-8 drops), the drug must be selected with a sterile syringe in a volume of 0.5-1 ml.
The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the expiration date.
Impact on ability to drive vehicles and operate machinery
None.
Composition
The solution contains:
Active ingredient: sterile mixture of purified filtrates of the phagolysates Klebsiella pneumonia, Klebsiella ozaenae, Klebsiella rhinoscleromatis 10 ml.
Excipients: 8-hydroxyquinoline sulfate monohydrate 0.0001 g / ml.
Dosage and administration
The drug is used for oral administration (by mouth), in the form of enemas, applications, irrigation, wound, vagina, uterus, nose, sinuses, as well as in drained cavities: abscesses, abdominal, pleural , bladder, renal pelvis.
Inside, the drug is taken on an empty stomach 0.5-1 hour before a meal.
Recommended doses of the drug: The age of the patient is 0-6 months - 5 doses per 1 dose when the drug is administered orally (ml) - 10 doses per 1 dose when the drug is administered in an enema (ml).
Age of the patient 6-12 months - 10 doses per 1 dose when the drug is administered orally (ml) - 20 doses per 1 dose when the drug is administered in an enema (ml).
Age of the patient from 1 year to 3 years - 15 doses per 1 dose when the drug is administered orally (ml) - 20-30 doses per 1 dose when the drug is administered in an enema (ml).
Age of the patient from 3 to 8 years - 20 doses per 1 dose when the drug is administered orally (ml) - 30-40 doses per 1 dose when the drug is administered in an enema (ml).
Patient age from 8 years and older - 20-30 doses per 1 dose with the drug inside (ml) - 40-50 doses per 1 dose with the drug in enema (ml).
Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by ingestion.
If the cavity of the purulent lesion is treated with chemical antiseptics, it should be washed with a sterile 0.9% sodium chloride solution before using the bacteriophage.
In the treatment of ozena and scleromas, the drug is used for washing the nasal cavity and mucous membrane of the upper respiratory tract, for introducing into the sinus cavity (according to clinical indications), as well as for damage to the pharynx, larynx, trachea in the form of inhalation (without heating and using ultrasound) . The dose of the drug for the treatment of mucous membranes of the nose and upper respiratory tract is 10-20 ml. After washing the mucous membranes in the nasal cavity, in turn, in each nasal passage, turunds moistened with the drug are injected, and left for 1 hour. The procedure is repeated 2-3 times a day for 20-40 days. Since ozena and scleroma are chronic diseases, in order to prevent exacerbations, it is recommended to conduct 20-40 day courses of treatment according to the above scheme once a year.
In the treatment of tonsillitis, pharyngitis, laryngitis, the drug is used to rinse the mouth and pharynx Zraza per day for 10-20 ml, the course of treatment is 7-10 days.
In the treatment of bronchitis, pneumonia, the drug is taken orally 3 times a day, 10-20 ml each, and is also used in the form of aerosols and inhalations (without heating and using ultrasound), the course of treatment is 15-20 days.
In the treatment of otitis media, the drug is used for washing and introducing 2-5 ml 1-3 times a day into the middle ear cavity. The course of treatment is 7-15 days.
In the treatment of inflammation of the sinuses of the nose, the drug is used to rinse the nasal cavity, nasopharynx and sinuses in a dose of 5-10 ml and introduction into the sinuses of 2-3 ml. The procedure is repeated daily once for 7-10 days. In addition, the drug is injected into the nasal cavity in the vice turunl moistened with a bacteriophage, in turn and in each nasal passage and left for 0.5-1 hours. The procedure is repeated 3 times a day, the course of treatment is 7-15 days.
In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of rinses of the oral cavity 3-4 times a day at a dose of 10-20 ml, as well as the introduction into the periodontal pockets of turundum soaked with Klebsiella bacteriophage for 5-10 minutes, the course of treatment is 7-10 days.
With conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days with purulent corneal ulcer - 4-5 drops per day for 7-10 days with purulent iridocyclitis - 6-8 drops every 3 hours in combination with oral administration at therapeutic dosages for 7-10 days .
In case of abscesses after opening and removing purulent contents, the drug is administered in an amount less than the volume of pus removed once daily, the course of treatment is 7-10 days.
With peritonitis and pleurisy, the drug is injected into the drained cavities of the abdominal and pleural through drainage tubes once daily 20-70 ml, the course of treatment is 10-15 days.
In osteomyelitis, the drug is injected into the wound cavity through turunds, drainage in the amount of 10-30 ml daily once, the course of treatment is 15-20 days.
In the treatment of suppuration of wounds, the drug is used in the form of irrigation, applications, dressings, introduction to the drainage at a dose of 5-50 ml, depending on the lesion at least once a day, kurstecheniya 10-15 days.
In the treatment of purulent-inflammatory gynecological diseases (suppuration of wounds, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis), the drug is used for irrigation, applications, injected into the wound cavity, vagina, uterus 5-20 ml once a day for 7- 10 days.
With cystitis, pyelonephritis, urethritis, the drug is taken orally at a therapeutic dose 3 times a day 1 hour before meals for 10-20 days. In the event that the cavity of the bladder or renal pelvis is drained, the drug is administered through a cystostomy or nephrostoma 1-3 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis, the course of treatment is 7-15 days.
With gastroenterocolitis, pancreatitis, cholecystitis, as well as intestinal dysbiosis, the bacteriophage is taken orally in age-related dosages 3 times a day 1 hour before meals for 7-15 days (according to clinical indications). With indomitable vomiting, the drug is used in the form of high enemas 2-3 times a day for 20-40 ml. With intestinal dysbiosis, the drug can be used with normoflora preparations.
For the prevention of nosocomial surgical infections, the drug is used to treat postoperative and freshly infected wounds at a dose of 5-50 ml, depending on the lesion, once a day for 5-7 days.
Use of the drug in children up to 1 year of age (including premature babies).
For gastroenterocolitis, pneumonia and sepsis of newborns, the drug is used, by mouth 2-3 times a day, 3-5 ml 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a gas tube or catheter) once daily in a dose of 5-10 ml. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible: The course of treatment is 7-15 days - (according to clinical indications). With a recurring course of the disease, repeated courses of treatment are possible.
In order to prevent the occurrence of nosocomial infections in newborns, the bacteriophage is used, according to epidemic indications, by 3-5 ml 3 times a day 30 minutes before feeding during the entire period of hospital stay.
In the treatment of omphalitis, pyoderma, infected wounds, the bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (a gauze cloth is moistened with a bacteriophage and applied to the umbilical wound or the affected area of the skin) for 7-15 days.
The use of the drug does not exclude the use of other antibacterial and anti-inflammatory drugs.
Side effects
Hypersensitivity to the components of the drug.
Drug interaction
The use of the drug is possible in combination with other drugs, including antibiotics.
Overdose
Not installed.
Storage conditions
Store in accordance with SP 3.3.2.1248-03 in a dry, dark place and out of the reach of children at 2 to 8 РC.
Shelf life
2 years.
Deystvuyushtee substance
bacteriophage klebsiell
Terms and conditions
By prescription
Dosage form
oral solution
Prescription
Prescription
Pregnant as prescribed by a doctor, For adults as prescribed by a doctor, Nursing mothers as prescribed by a doctor, For children prescribed by a doctor, For children from birth
Solution for oral administration, local and external use.
Packing
4 vials of 20 ml.
Pharmacological action of
The drug causes specific lysis of bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis.
Indications
Treatment and prevention of diseases caused by bacteria Klebsiella pneumoniae, Klebsiella ozaenae, Klebsiella rhinoscleromatis as part of complex therapy: Ozen, scleroma.
Diseases of the gastrointestinal tract (gastroenterocolitis, cholecystitis, pancreatitis, intestinal dysbiosis).
Inflammatory diseases of newborns and young children (gastroenterocolitis, intestinal dysbiosis, omphalitis, pemphigus, pyoderma, septicemia and septicopyemia of various localization).
Surgical infections (suppuration of wounds, purulent skin lesions, burns, peritonitis, pleurisy, mastitis, osteomyelitis, abscess).
Urogenital infections (cystitis, pyelonephritis, urethritis, endometritis, vulvitis, bartholinitis, colpitis, salpingo-oophoritis).
Purulent-inflammatory diseases of the ear, throat, nose, sinuses, mouth, pharynx, larynx, bronchi, lungs and pleura (otitis media, tonsillitis, pharyngitis, laryngitis, stomatitis, periodontitis, sinusitis, frontal sinusitis, bronchitis, pneumonia, pleurisy).
Post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcer and iridocyclitis.
Prevention of nosocomial infections caused by Klebsiella.
An important condition for effective phage therapy is a preliminary determination of the phage sensitivity of the pathogen.
Contraindications
Hypersensitivity to the components of the drug.
Use during pregnancy and lactation
Use of this drug during pregnancy and during lactation is possible in the presence of infections caused by phage-sensitive strains of Klebsiella (as recommended by a doctor).
Special instructions
Shake and shake the vial with the bacteriophage before use. The drug should be transparent and not contain sediment.
Attention! In case of turbidity, do not use the drug!
Due to the presence in the preparation of a nutrient medium in which bacteria from the environment can develop, causing clouding of the drug, the following rules must be observed when opening the bottle: Wash hands thoroughly.
Treat the cap with an alcohol-containing solution.
Remove the cap without opening the plug.
Do not place the cork with the inner surface on a table or other objects.
Do not leave vial open.
Store the opened bottle only in the refrigerator.
When using small doses (2-8 drops), the drug must be selected with a sterile syringe in a volume of 0.5-1 ml.
The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the expiration date.
Impact on ability to drive vehicles and operate machinery
None.
Composition
The solution contains:
Active ingredient: sterile mixture of purified filtrates of the phagolysates Klebsiella pneumonia, Klebsiella ozaenae, Klebsiella rhinoscleromatis 10 ml.
Excipients: 8-hydroxyquinoline sulfate monohydrate 0.0001 g / ml.
Dosage and administration
The drug is used for oral administration (by mouth), in the form of enemas, applications, irrigation, wound, vagina, uterus, nose, sinuses, as well as in drained cavities: abscesses, abdominal, pleural , bladder, renal pelvis.
Inside, the drug is taken on an empty stomach 0.5-1 hour before a meal.
Recommended doses of the drug: The age of the patient is 0-6 months - 5 doses per 1 dose when the drug is administered orally (ml) - 10 doses per 1 dose when the drug is administered in an enema (ml).
Age of the patient 6-12 months - 10 doses per 1 dose when the drug is administered orally (ml) - 20 doses per 1 dose when the drug is administered in an enema (ml).
Age of the patient from 1 year to 3 years - 15 doses per 1 dose when the drug is administered orally (ml) - 20-30 doses per 1 dose when the drug is administered in an enema (ml).
Age of the patient from 3 to 8 years - 20 doses per 1 dose when the drug is administered orally (ml) - 30-40 doses per 1 dose when the drug is administered in an enema (ml).
Patient age from 8 years and older - 20-30 doses per 1 dose with the drug inside (ml) - 40-50 doses per 1 dose with the drug in enema (ml).
Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by ingestion.
If the cavity of the purulent lesion is treated with chemical antiseptics, it should be washed with a sterile 0.9% sodium chloride solution before using the bacteriophage.
In the treatment of ozena and scleromas, the drug is used for washing the nasal cavity and mucous membrane of the upper respiratory tract, for introducing into the sinus cavity (according to clinical indications), as well as for damage to the pharynx, larynx, trachea in the form of inhalation (without heating and using ultrasound) . The dose of the drug for the treatment of mucous membranes of the nose and upper respiratory tract is 10-20 ml. After washing the mucous membranes in the nasal cavity, in turn, in each nasal passage, turunds moistened with the drug are injected, and left for 1 hour. The procedure is repeated 2-3 times a day for 20-40 days. Since ozena and scleroma are chronic diseases, in order to prevent exacerbations, it is recommended to conduct 20-40 day courses of treatment according to the above scheme once a year.
In the treatment of tonsillitis, pharyngitis, laryngitis, the drug is used to rinse the mouth and pharynx Zraza per day for 10-20 ml, the course of treatment is 7-10 days.
In the treatment of bronchitis, pneumonia, the drug is taken orally 3 times a day, 10-20 ml each, and is also used in the form of aerosols and inhalations (without heating and using ultrasound), the course of treatment is 15-20 days.
In the treatment of otitis media, the drug is used for washing and introducing 2-5 ml 1-3 times a day into the middle ear cavity. The course of treatment is 7-15 days.
In the treatment of inflammation of the sinuses of the nose, the drug is used to rinse the nasal cavity, nasopharynx and sinuses in a dose of 5-10 ml and introduction into the sinuses of 2-3 ml. The procedure is repeated daily once for 7-10 days. In addition, the drug is injected into the nasal cavity in the vice turunl moistened with a bacteriophage, in turn and in each nasal passage and left for 0.5-1 hours. The procedure is repeated 3 times a day, the course of treatment is 7-15 days.
In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of rinses of the oral cavity 3-4 times a day at a dose of 10-20 ml, as well as the introduction into the periodontal pockets of turundum soaked with Klebsiella bacteriophage for 5-10 minutes, the course of treatment is 7-10 days.
With conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days with purulent corneal ulcer - 4-5 drops per day for 7-10 days with purulent iridocyclitis - 6-8 drops every 3 hours in combination with oral administration at therapeutic dosages for 7-10 days .
In case of abscesses after opening and removing purulent contents, the drug is administered in an amount less than the volume of pus removed once daily, the course of treatment is 7-10 days.
With peritonitis and pleurisy, the drug is injected into the drained cavities of the abdominal and pleural through drainage tubes once daily 20-70 ml, the course of treatment is 10-15 days.
In osteomyelitis, the drug is injected into the wound cavity through turunds, drainage in the amount of 10-30 ml daily once, the course of treatment is 15-20 days.
In the treatment of suppuration of wounds, the drug is used in the form of irrigation, applications, dressings, introduction to the drainage at a dose of 5-50 ml, depending on the lesion at least once a day, kurstecheniya 10-15 days.
In the treatment of purulent-inflammatory gynecological diseases (suppuration of wounds, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis), the drug is used for irrigation, applications, injected into the wound cavity, vagina, uterus 5-20 ml once a day for 7- 10 days.
With cystitis, pyelonephritis, urethritis, the drug is taken orally at a therapeutic dose 3 times a day 1 hour before meals for 10-20 days. In the event that the cavity of the bladder or renal pelvis is drained, the drug is administered through a cystostomy or nephrostoma 1-3 times a day, 20-50 ml into the bladder and 5-7 ml into the renal pelvis, the course of treatment is 7-15 days.
With gastroenterocolitis, pancreatitis, cholecystitis, as well as intestinal dysbiosis, the bacteriophage is taken orally in age-related dosages 3 times a day 1 hour before meals for 7-15 days (according to clinical indications). With indomitable vomiting, the drug is used in the form of high enemas 2-3 times a day for 20-40 ml. With intestinal dysbiosis, the drug can be used with normoflora preparations.
For the prevention of nosocomial surgical infections, the drug is used to treat postoperative and freshly infected wounds at a dose of 5-50 ml, depending on the lesion, once a day for 5-7 days.
Use of the drug in children up to 1 year of age (including premature babies).
For gastroenterocolitis, pneumonia and sepsis of newborns, the drug is used, by mouth 2-3 times a day, 3-5 ml 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a gas tube or catheter) once daily in a dose of 5-10 ml. A combination of rectal (in the form of high enemas) and oral administration of the drug is possible: The course of treatment is 7-15 days - (according to clinical indications). With a recurring course of the disease, repeated courses of treatment are possible.
In order to prevent the occurrence of nosocomial infections in newborns, the bacteriophage is used, according to epidemic indications, by 3-5 ml 3 times a day 30 minutes before feeding during the entire period of hospital stay.
In the treatment of omphalitis, pyoderma, infected wounds, the bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (a gauze cloth is moistened with a bacteriophage and applied to the umbilical wound or the affected area of the skin) for 7-15 days.
The use of the drug does not exclude the use of other antibacterial and anti-inflammatory drugs.
Side effects
Hypersensitivity to the components of the drug.
Drug interaction
The use of the drug is possible in combination with other drugs, including antibiotics.
Overdose
Not installed.
Storage conditions
Store in accordance with SP 3.3.2.1248-03 in a dry, dark place and out of the reach of children at 2 to 8 РC.
Shelf life
2 years.
Deystvuyushtee substance
bacteriophage klebsiell
Terms and conditions
By prescription
Dosage form
oral solution
Prescription
Prescription
Pregnant as prescribed by a doctor, For adults as prescribed by a doctor, Nursing mothers as prescribed by a doctor, For children prescribed by a doctor, For children from birth
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