bacitracin, neomycin | Baneocin Ointment 250 IU / g + 5000 IU / g 20 g

Release form

Ointment for external use

Packaging

Tube 20 g.

Pharmacological action

Baneocin is a combined antibacterial drug for external use. It contains two antibiotics that have a bactericidal effect, neomycin and bacitracin.

Bacitracin is a polypeptide antibiotic that inhibits bacterial cell wall synthesis.

Neomycin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis.

Bacitracin is active against gram-positive (Streptococcus spp. / including hemolytic streptococcus /, Staphylococcus spp.) and some gram-negative microorganisms. Bacitracin resistance is rare. It has good tissue tolerance of inactivation by biological products, blood and tissue components are not observed.

Neomycin is active against gram-positive and gram-negative bacteria.

By using a combination of these two antibiotics, a broad spectrum of action of the drug and synergy of action against a number of microorganisms, for example, staphylococci, are achieved.

Indications

Focal skin infections, for example: Boils, carbuncles (after surgical treatment), scalp, purulent hydrodenitis, pseudofurunculosis, paronychia

Bacterial skin infections of limited prevalence, for example: contagious impetigo, infected varicose ulcers, with secondary bacterial eczema, secondary infection with dermatoses, cuts, abrasions, burns, cosmetic surgery and skin transplantation (also for prophylactic use and under dressing).

After major and minor surgical interventions

Baneocin ointment can be used as an additional treatment in the postoperative period: Applying Baneocin ointment to gauze strips is preferable for targeted local treatment of patients with infected cavities and wounds (for example, infections of the external auditory canal, wounds or surgical incisions healing by secondary intention).

Use during pregnancy and lactation

In cases where it is impossible to control the absorption of the drug in pregnant and lactating women, Baneocin should be used with caution. Like all other aminoglycosides, neomycin crosses the placental barrier. With the systemic use of aminoglycosides in a high dose, the development of damage to the cochlear apparatus in the fetus was noted.

Composition

1 g ointment contains:

Active substances: Zinc-Bacitracin 250 IU, Neomycin sulfate 5000 IU (5 mg).

Dosage and administration

Apply the necessary amount of ointment or powder to the treatment site, if appropriate, under a dressing.

As a rule, in adults and children Baneocin powder is used two to four times a day, while Baneocin ointment is used two to three times a day.

In patients with burns occupying more than 20% of the body surface, Baneocin powder should not be used more than once a day, especially in case of decreased renal function, since there may be absorption of the active ingredient.

When applied topically, the dose of neomycin should not exceed 1 g per day (corresponding to 200 g of powder or ointment) for 7 days. With a repeated course, the maximum dose should be halved.

Side effects

Allergic reactions: with prolonged use - redness, dry skin, skin rash, itching. In the treatment of chronic dermatoses or chronic otitis media, Baneocin promotes sensitization to other drugs, including neomycin. This may result in poor treatment effectiveness. Allergic reactions of the type of contact eczema were less common than usual (associated with cross-allergy to other aminoglycosides in approximately 50% of cases).

Systemic effects: for extensive skin lesions, the possibility of drug absorption and the development of oto- and nephrotoxic effects and neuromuscular conduction disorders should be taken into account.

Drug interaction

If systemic absorption occurs, concomitant administration of cephalosporins or other aminoglycoside antibiotics may increase the likelihood of a nephrotoxic reaction.

The simultaneous use of diuretics such as ethacrylic acid or furosemide can provoke an oto- and nephrotoxic effect.

Baneocin absorption may potentiate neuromuscular block phenomena in patients receiving drugs, anesthetics, and muscle relaxants.

Storage Conditions

Store below 25 РC in a dark place. The powder should be stored in a dry place.

The Expiration of

is 3 years.

active ingredient

bacitracin, Neomycin

Terms leave through pharmacies

without prescription

lekarstvennaja form

ointment

Prescribing

For adults, For children prescribed by a doctor, Nursing mothers as prescribed by a doctor, Pregnant women for medical appointments

Indications

Indications

Skin infections, Boils, Trophic ulcers, Minor skin lesions

Merck KGaA & Co., Switzerland