Babezan 12% 100ml

DESCRIPTION

Babezan 12% (Babezan 12%) - injection solution for the treatment and prevention of blood parasitic diseases in horses, cattle, sheep and dogs. In appearance, the drug is a clear yellow solution.

COMPOSITION

Contains in 1 ml as an active ingredient imidocarb dipropionate 120 mg, respectively, and as auxiliary substances: benzalkonium chloride, high molecular weight polyvinylpyrrolidone and water for injection.

PHARMACOLOGICAL PROPERTIES

Babezan 12% solution for injections belongs to the antiprotozoal drugs of the imidazoline group.

Imidocarba dipropionate, which is part of the drug Babesan 12% solution for injection, is active against Babesia bovis, Babesia ovis, Babesia bigemina, Babesia colchica, Babesia equi, Babesia divergens, Babesia canis, Babesia caballi, Babesai gibsonia annulata, Francileella annulata , Theileria sergenti, Theileria mutans, Theileria orientalis, Theileria ovis, Theileria recondite, Theileria tarandirangiferis, Nuttallia equi, Anaplasma marginale, Anaplasma ovis, and Ehrlichia sashs.

The mechanism of the antiprotozoal action of imidocarb is associated with the suppression of the intake of inositol, which is necessary for the vital activity of the blood parasite, as well as with the disruption of the formation and use of polyamines by parasites.

After parenteral administration of the drug, the therapeutic concentration of imidocarb in the blood is reached after 18-24 hours and is maintained at the piroplasmostatic level for 4-6 weeks. Imidocarb dipropionate accumulates mainly in the kidneys and liver; excreted from the body mainly in the urine.

Babezan 12% solution for injections, according to the degree of impact on the body, belongs to moderately hazardous substances (hazard class 3 according to GOST 12 .1. 007-7 6), in the recommended doses it does not have local irritating, cumulative, embryotoxic and mutagenic properties.

PURPOSE

Babezan 12% solution for injections is prescribed for therapeutic and prophylactic purposes in horses, cattle, sheep and dogs with blood parasites - acute, chronic and subclinical babesiosis, anaplasmosis and nuttaliasis, as well as for mixed invasions.

DOSAGE AND APPLICATION

For dogs Babesan 12% solution for injection is used for babesiosis for therapeutic purposes, once subcutaneously at a dose of 4 mg imidocarb per 1 kg of animal weight, which corresponds to 0.03 ml / kg of Babesan 12% solution for injections.

If babesia is found in a blood smear a day after using the drug, it is re-injected at the same dose.

For prophylactic purposes, when clinical signs of babesiosis appear or within a week after the animals move to zones unfavorable for this disease, Babezan 12% solution for injection is used in dogs once in a therapeutic dose.

The protective effect after injection of the drug lasts for 4 weeks.

For cattle, sheep and horses Babezan 12% solution for injection is used for babesiosis and nuttaliasis for therapeutic purposes, once intramuscularly at a dose of 2.5 mg of imidocarb per 1 kg of animal weight, which corresponds to 2.0 ml of the drug per 100 kg of animal weight.

In the treatment of anaplasmosis and mixed blood-parasitic diseases (anaplasmosis + babesiosis), the dose is increased to 5 mg of imidocarb per 1 kg of animal weight, which corresponds to 4.0 ml of Babesan 12% solution for: injection per 100 kg of animal weight.

For prophylactic purposes in the event of an attack (or threat of attack) of ticks carrying blood parasitic diseases, Babezan 12% solution for: injection is administered to animals once intramuscularly at a dose of 2.5 ml per 100 kg of animal weight (3 mg of imidocarb per 1 kg of animal weight).

The protective effect of the drug lasts for 30-45 days, depending on the epizootic situation and the physiological state of the animal.

SPECIAL INSTRUCTIONS

The simultaneous use of Babezan 12% solution for injection with organochlorine, organophosphorus drugs and other cholinesterase inhibitors is not allowed.

Slaughter of cattle, sheep and horses for meat is allowed no earlier than 28 days after the last application of Babezan 12% solution for injection. The meat of animals that were forcedly killed before the expiration of the specified period can be used as feed for fur animals.

Milk obtained from animals after the application of Babezan 12% solution for injection is allowed to be used for food purposes no earlier than 4 days after the last injection of the drug. The milk obtained earlier than the established period after boiling can be used in animal feed.

CONTRAINDICATIONS

A contraindication for the use of the drug is the individual hypersensitivity of animals to the components of the drug (including a history). Do not use the medicinal product within 4 weeks after vaccination with live vaccine against babesiosis or anaplasmosis.

In case of an overdose and / or increased individual sensitivity of the animal to the drug, complications may develop (bradycardia, increased and impaired breathing, anorexia, profuse salivation, lacrimation, sweating, muscle tremors, frequent urination and defecation), in these cases, 1% atropine solution is prescribed subcutaneously, symptomatic agents and desensitizing therapy.

In rare cases, a local reaction is possible in the form of hyperemia or painful swelling at the injection site of the drug, which disappears spontaneously after 1-2 days. Re-administration may be accompanied by a decrease in blood pressure.

Due to the possible painful reaction, the drug should not be administered in one place to large animals in a volume exceeding 10 ml and to small animals in a volume exceeding 2.5 ml.

For puppies, pregnant and lactating females, the drug can be used after consultation with a veterinarian. Milk from lactating females of productive animals can be used for food purposes and for feeding offspring not earlier than the established date.

SIDE EFFECTS

When using Babezan 12% solution for injection according to this instruction, side effects and complications in animals, as a rule, are not observed. In rare cases, hypersalivation, tremor of the muscles of the abdominal wall and a local reaction in the form of hyperemia or swelling at the injection site, which disappears after 1-2 days, are possible.

With the mass death of blood parasites and the destruction of erythrocytes after the use of Babesan 12% solution for injection in animals, intoxication may develop. In this case, it is necessary to carry out intensive therapy, including intravenous administration of electrolyte solutions and hepatoprotectors.

It is advisable to use antihistamines for animals with clinical signs of babesiosis before the administration of Babesan 12% solution for injection.

SHELF LIFE AND STORAGE

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 2 years from the date of production, after the first opening of the bottle - 28 days. It is prohibited to use the medicinal product after the expiration date.

Store the medicinal product in the manufacturer's closed packaging in a dry place protected from direct sunlight, separately from food and feed, at a temperature of 5 В° C to 25 В° C.

PACKAGING

Babezan 12% solution for injection is released packaged in 100 ml each in glass vials made of dark glass, which are sealed with rubber stoppers, reinforced with aluminum caps. Each unit of consumer packaging is supplied with instructions for using the drug.

Specifications

Bonus points

0

KolVUP

50

Manufacturer

Agrovetzashita

Temperature regime

from +5 to +25

Teaser

for the treatment and prevention of blood parasitic diseases in horses, cattle, sheep and dogs