Azithromycin capsules 250mg, No. 6

Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:
Ј Infections of the upper respiratory tract and ENT organs (pharyngitis / tonsillitis, sinusitis, otitis media);
Ј Infections of the lower respiratory tract: acute bronchitis, exacerbation of chronic bronchitis, incl. caused by atypical pathogens;
Ј Infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses);
Ј The initial stage of Lyme disease (borreliosis) - erythema migrans (Erythemamigrans);
Chlamydiatrachomatis infections of the urinary tract (urethritis, cervicitis)

Set individually, taking into account the nosological form, the severity of the course of the disease and the sensitivity of the pathogen. Adults inside - 0.25-1 g 1 time /; children - 5-10 mg / kg 1 time / Duration of admission 2-5 days

1 capsule contains:
active substance:

azithromycin dihydrate (equivalent to anhydrous azithromycin) - 250 mg.

Ј Hypersensitivity to antibiotics of the macrolide group;
Ј Severe violations of liver and kidney function;
Ј Children under 12 years of age with a body weight of less than 45 kg (for this dosage form);
Ј Breast-feeding;
Ј Simultaneous reception with ergotamine and dihydroergotamine.

Pharmacological action
Azithromycin is a broad-spectrum bacteriostatic antibiotic from the group of macrolides-azalides. Possesses a wide spectrum of antimicrobial action. The mechanism of action of azithromycin is associated with the suppression of protein synthesis of the microbial cell. By binding to the 50S - subunit of the ribosome, it inhibits peptide translocase at the stage of translation and suppresses protein synthesis, slowing down the growth and reproduction of bacteria. In high concentrations, it has a bactericidal effect.
Has activity against a number of gram-positive, gram-negative, anaerobic, intracellular and other microorganisms.
Indications
Infectious and inflammatory diseases caused by microorganisms sensitive to the drug:
Ј Infections of the upper respiratory tract and ENT organs (pharyngitis / tonsillitis, sinusitis, otitis media);
Ј Infections of the lower respiratory tract: acute bronchitis, exacerbation of chronic bronchitis, incl. caused by atypical pathogens;
Ј Infections of the skin and soft tissues (erysipelas, impetigo, secondarily infected dermatoses);
Ј The initial stage of Lyme disease (borreliosis) - erythema migrans (Erythemamigrans);
Infections of the genitourinary tract caused by Chlamydiatrachomatis (urethritis, cervicitis).
Contraindications
Ј Hypersensitivity to antibiotics of the macrolide group;
Ј Severe violations of liver and kidney function;
Ј Children under 12 years of age with a body weight of less than 45 kg (for this dosage form);
Ј Breast-feeding;
Ј Simultaneous reception with ergotamine and dihydroergotamine.
Dosage and administration
Set individually, taking into account the nosological form, the severity of the disease and the sensitivity of the pathogen. Adults inside - 0.25-1 g 1 time /; children - 5-10 mg / kg 1 time / Duration of admission 2-5 days

Side effects
They are rare (in 1% of cases or less).
From the digestive system: melena, cholestatic jaundice, nausea, vomiting, diarrhea, constipation, decreased appetite, gastritis, a reversible moderate increase in the activity of liver enzymes.
From the urinary system: nephritis.
From the reproductive system: vaginal candidiasis.
From the side of the cardiovascular system: palpitations, chest pains.
From the side of the central nervous system and peripheral nervous system: dizziness, headache, vertigo, drowsiness.
Overdose
Symptoms: nausea, temporary hearing loss, vomiting, diarrhea.
Treatment: gastric lavage, symptomatic therapy.