Aversectin ointment 30g

DESCRIPTION

Aversectin ointment is a drug for the treatment of arachnoentomoses in carnivores and rabbits. Dosage form: ointment for external use. In appearance, the drug is a mass of uniform consistency, white with a yellowish tinge.

COMPOSITION

Aversectin ointment as an active ingredient contains aversectin C - 0.05%, as well as auxiliary substances: polyethylene oxide - 1500, distilled glycerin and polyethylene oxide - 400.

PHARMACOLOGICAL PROPERTIES

Aversectin ointment is an insectoacaricidal drug of contact and systemic action from the class of macrocyclic lactones.

Aversectin C, which is a part of Aversectinova Ointment, is active against larval and mature phases of development of sarcoptoid ticks (Sarcoptes canis, Sarcoptes vulpis, Notoedres cati, Otodectes cynotis, Psoroptes cuniculi) and demodectic and canine insects (Demode Ctenocephalides felis, Linognathus setotus, Trichodectes canis) parasitizing dogs, cats, fur-bearing animals and rabbits.

The mechanism of action of aversectin C consists in its effect on the magnitude of the current of chlorine ions through the membranes of the nerve and muscle cells of the parasite. The main targets are glutamate-sensitive chlorine channels, as well as gamma aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of nerve impulses, which leads to paralysis and death of the parasite.

When the ointment is applied to the skin, aversectin C has a contact effect in the places of localization of ectoparasites (on the skin, in the hair follicles and sebaceous glands), and after absorption it has a systemic insectoacaricidal effect.

The maximum concentration of aversectin C in the blood serum after applying the ointment is observed on the 3-5th day. Aversectin is excreted from the body, mainly with feces in an unchanged form within 10-12 days.

Ointment aversectin according to the degree of impact on the body refers to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in recommended doses does not have a local irritant, resorptive-toxic, sensitizing, embryotoxic, teratogenic and mutagenic effect. Well tolerated by dogs, cats, fur animals and rabbits of different breeds and ages. Toxic to bees, as well as fish and other aquatic organisms.

Aversectin ointment should not be used in conjunction with avermectin-containing and other antiparasitic drugs for treating animals.

PURPOSE

Aversectin ointment is used to treat dogs, cats and fur-bearing animals with sarcoptic mange, notoedrosis, otodectosis, demodicosis and entomoses; rabbits - with psoroptosis.

APPLICATION

In animals suffering from sarcoptic mange, notoedrosis, demodectic mange, hair is preliminarily cut off in the affected areas, crusts and scabs are removed, and then a thin layer of ointment is applied with a spatula (glass stick or cotton-gauze swab), evenly spreading from the periphery to the center, and rubbed into the affected areas with the capture of borderline healthy skin up to 1 cm.

To prevent licking of the drug, the animals wear a neck collar, muzzle or fix the jaws with braid, which are removed after the coat is completely dry.

The treatment is carried out 2-5 times with an interval of 5-7 days until the animal's clinical recovery, which is confirmed by two negative results of microscopic examinations of scrapings from the affected skin areas.

Animals with extensive areas of skin lesions are treated in two doses with an interval of one day, applying the ointment first on one half of the affected surface of the body, and then on the other.

In case of acarosis complicated by infection of bacterial or fungal etiology, it is recommended to use immunomodulatory, antibacterial or antifungal agents.

With the ear form of scabies in dogs, cats, fur-bearing animals and rabbits, the external auditory canal is cleaned of scabs and crusts with a damp swab, then ointment is applied to each ear. The ointment can be melted (in the packaging of the manufacturer) in hot water to a liquid state and instilled into the ears in a warm form.

For a more complete treatment of the entire surface of the ear and the auditory canal, the auricle is folded in half and its base is lightly massaged.

Processing is carried out 1-2 times with an interval of 5-7 days. In advanced cases of the disease complicated by otitis media, antibacterial and anti-inflammatory drugs are prescribed. If necessary, the course of treatment is repeated under the control of microscopy of scrapings.

Both ears must be treated with aversectin ointment, even if only one ear is affected by ticks.

In case of entomoses (aphanipterosis, linognatosis, trichodectosis), the ointment is rubbed into the skin with a brush (against hair growth) into places where insects accumulate and then the wool is combed with a comb.

To prevent re-infestation of fleas, the animals are replaced with bedding. Repeated treatments are carried out according to indications, but not more often than 1 time per month.

The frequency of application and the interval between animal treatments are indicated in the table:

Kind of animal Disease Multiplicity of application, interval Note

Rabbits psoroptosis 2 times with an interval of 5-7 days * for ease of use, the ointment can be melted (in the manufacturer's packaging) in hot water to a liquid state and applied warm for insertion into the auricles or rubbing into the affected areas of the body

Cats, dogs, fur animals otodectosis, notoedrosis, sarcoptic mange 2 times with an interval of 5-7 days *

Dogs demodicosis squamous form 3 times with an interval of 5-7 days treatment of pustular and mixed forms should be carried out in a comprehensive manner using etiotropic, pathogenetic and symptomatic drugs

pustular form 7 times with an interval of 7 days

mixed form 7 times with an interval of 7 days *. With multiple lesions with an interval of 5 days *

Dogs, cats, fur animals entomoses (trichodectosis, linognatosis, aphanipterosis) 2 times with an interval of 7-10 days * the ointment is rubbed into the skin against the growth of wool (it can be melted) in places where insects accumulate and in the back of the head. In order to prevent the emergence of fleas and re-infestation of animals, the litter is replaced

* If necessary, the treatment is repeated (with acarosis under the control of microscopy of scrapings).

Violations of the drug use regimen should be avoided, as this can lead to a decrease in its effectiveness. If the next treatment is missed, it should be carried out as soon as possible in the same dose.

CONTRAINDICATIONS

A contraindication to the use of Ointment aversectinova is the individual hypersensitivity of the animal to the components of the drug (including a history).

Patients with infectious diseases, convalescent and emaciated animals cannot be processed. Pregnant and lactating females, as well as puppies and kittens under 2 months of age, cannot be processed.

OVERDOSE

In case of an overdose of the drug, the animal may experience weakness, tremor, salivation. There are no specific means of detoxification of averse C, general measures are used to remove the drug from the body.

SIDE EFFECTS

As a rule, there are no side effects and complications when using aversectin ointment in accordance with this instruction. In case of increased individual sensitivity of the animal to the components of the drug and the appearance of allergic reactions, the drug should be washed off with water and detergent and, if necessary, prescribe antihistamines.

The peculiarities of the action of the drug during its first use or withdrawal were not revealed.

Slaughter of rabbits for meat is allowed no earlier than 14 days after the last application of Aversectin Ointment. In the event of the forced slaughter of animals before the established deadline, the meat can be used as feed for fur animals.

PRECAUTIONS

When working with aversectin ointment, you should follow the general rules of personal hygiene and safety measures provided for when working with medicines. Animal handling should be carried out with rubber gloves. While working with the drug, it is not allowed to smoke, drink or eat. At the end of work, you should thoroughly wash your hands with warm water and soap, wash and dry your gloves.

The animal should not be stroked and kept close to small children within 24 hours after treatment. People with hypersensitivity to the components of the drug should avoid direct contact with aversectin ointment. It is forbidden to use empty containers from the medicinal product for household purposes. They are placed in a plastic bag and disposed of with household waste.

FIRST AID MEASURES

In case of accidental contact of the drug on the skin, it must be immediately washed off with soap and water, in case of contact with the eyes, rinse them for several minutes with running water. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (you should have instructions for use of the drug or a label with you).

SPECIAL INSTRUCTIONS

Unused medicinal product

Specifications

KolVUP

84

Manufacturer

Pharmbiomedservice

Teaser

for the treatment of dogs, cats and fur animals with sarcoptic mange, notoedrosis, otoectosis, demodicosis and entomoses; rabbits - with psoroptosis