Aversect K&C 0.2% injectable 5ml
DESCRIPTION
Aversect-2 (Aversect-2) is an injection solution for the treatment and prevention of arachno-entomoses and nematodes in ruminants and pigs. In appearance, the drug is a clear, light yellow liquid.
COMPOSITION
Aversect K & S as an active ingredient contains avermectin complex (aversectin C1), obtained on the basis of waste products of the soil fungus Streptomyces avermitilis, as well as auxiliary components.
PHARMACOLOGICAL PROPERTIES
Aversect K & S has a wide spectrum of antiparasitic action, is active against the roundworms Toxocara canis, Toxocara mystax, Toxascaris leonina, Uncinaria spp., Ancylostoma spp., Dirofilaria immitis, Trichuris vulpis, Sarcoptes spp. Mites, Demoxis spp., Otodedectes. and insects Ctenocephalides spp., Linognathus spp., Trichodectes canis, parasitizing dogs and cats. The mechanism of action of aversectin C1 lies in its effect on the magnitude of the current of chlorine ions through the membranes of the nerve and muscle cells of the parasite. The main targets are glutamate-sensitive chlorine channels, as well as gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of nerve impulses, which leads to paralysis and death of the parasite. After parenteral administration, aversectin C1 is rapidly absorbed from the injection site and distributed in the organs and tissues of the animal, providing a long-term parasiticidal effect. The maximum level of aversectin C1 in the blood is observed 24 hours after the subcutaneous injection of the drug, with a subsequent decrease by 5 days. The drug is excreted from the body of the animal with urine and bile, in lactating females - partly with milk. In terms of the degree of impact on the body of warm-blooded animals, Aversect K & S is classified as a low-hazard substance and in recommended doses does not have embryotoxic, teratogenic and mutagenic effects. with a subsequent decrease by 5 days. The drug is excreted from the body of the animal with urine and bile, in lactating females - partly with milk. In terms of the degree of impact on the body of warm-blooded animals, Aversect K & S is classified as a low-hazard substance and in recommended doses does not have embryotoxic, teratogenic and mutagenic effects. with a subsequent decrease by 5 days. The drug is excreted from the body of the animal with urine and bile, in lactating females - partly with milk. In terms of the degree of impact on the body of warm-blooded animals, Aversect K & S is classified as a low-hazard substance and in recommended doses does not have embryotoxic, teratogenic and mutagenic effects.
INDICATIONS
Prescribed to dogs and cats for prophylactic and therapeutic purposes for nematodes and arachno-entomoses (demodicosis, otodectosis, notoedrosis, sarcoptic mange, sifunculatosis).
DOSES AND METHOD OF APPLICATION
Aversect K & S is administered to animals in compliance with the rules of asepsis and antiseptics subcutaneously or intramuscularly at the rate of 0.2 mg of the active substance (aversectin C1) per 1 kg of animal weight, which corresponds to medium and large dogs - 0.4 ml of 0.5% Aversect solution Рљ & РЎ per 10 kg of animal weight, dogs weighing less than 10 kg and cats - 0.1 ml of 0.2% solution of Aversect K & РЎ per 1 kg of animal weight.
With nematoses and entomoses, the drug is used once, with sarcoptic mange, notoedrosis and otodectosis - twice with an interval of 7-10 days, with demodicosis - repeatedly until the animal recovers with an interval of 7-10 days. The clinical recovery of the animal is confirmed by two negative results of acarological studies of skin scrapings.
Treatment of animals with acarosis is recommended to be carried out in a complex with the use of immunomodulating, antifungal and antimicrobial drugs. In order to prevent re-infestation of fleas, the animal is replaced with a litter or treated with an insecticidal agent in accordance with the instructions for use.
SIDE EFFECTS
Allergic reactions are possible in hypersensitive animals. With proper use and dosage, side effects are usually not observed. With a significant overdose of the drug in animals, edema may appear at the injection site, impaired coordination of movements, recumbency. In this case, it is necessary to stop the drug administration.
CONTRAINDICATIONS
Increased individual sensitivity to the drug. Use with caution in puppies and kittens up to 7 weeks of age, pregnant and lactating females, as well as weakened and old animals. Due to the pronounced pedigree sensitivity to avermectins, the drug should not be prescribed to dogs of the collie, bobtail and sheltie breeds. Do not use in conjunction with avermectin-containing and other antiparasitic drugs for treating animals.
SPECIAL INSTRUCTIONS
No special precautions are taken. In case of accidental contact of the product on the mucous membrane of the eyes or on the skin, wash them thoroughly with water. In case of accidental swallowing of the drug, you must drink a few glasses of water, and then take 10 - 20 tablets of activated carbon. Seek medical attention if necessary. It is recommended to have a container label or instructions for use of the drug with you. There are no specific detoxification agents; general measures are used to remove the drug from the body.
SHELF LIFE AND STORAGE
In a dry place, protected from direct sunlight and out of reach of children and animals. Separated from food and feed at temperatures from 0 to 30 В° C. Shelf life - 2 years, after opening the bottle - no more than 24 days.
PACKAGING
Packaged in 5 ml glass bottles, which are packed in cardboard boxes.
Specifications
KolVUP
ten
Manufacturer
Pharmbiomedservice
Teaser
injection solution for the prevention and treatment of nematodes and arachno-entomoses (demodicosis, otodectosis, notoedrosis, sarcoptic mange, sifunculatosis)