Aversect-2 VK 20% injection 20ml
DESCRIPTION
Aversect-2 VK is a broad-spectrum antiparasitic agent. Yellow solution for intradermal administration only.
COMPOSITION
Aversectin C (20 g / 100 ml), benzyl alcohol.
PHARMACOLOGICAL PROPERTIES
Aversect-2 VK is effective against pathogens of hypodermosis, larvae of Hypoderma bovis and Hypoderma lineatum stages I, II, III, gastrointestinal (Ostertagia spp., Haemonchus placei, Trichostrongylus spp., Cooperia spp., Oesophagostomodum radiatum spp., Strongy papillosas, Bunostomum spp., Thelazia spp.) and pulmonary (Dictyocaulus filaria) nematodes, psoroptosis, sarcoptic mange, chorioptosis and syphunculosis, as well as ixodid ticks.
The mechanism of action of the active ingredient, aversectin C, consists in its effect on the magnitude of the current of chlorine ions through the membranes of the nerve and muscle cells of the parasite. The main targets are glutamate-sensitive chlorine channels and gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of nerve impulses, which leads to paralysis and death of the parasite.
In terms of oral toxicity, the drug belongs to the 3rd hazard class (GOST 12.1.007-76) and the 2nd hazard class (hygienic classification of pesticides, MR No. 2001/26 dated 04.16.01), respectively. The drug does not have embryotoxic, teratogenic and mutagenic effects. Aversect-2 VK does not cause allergic reactions.
The period of reaching the maximum concentration (Cmax) of aversectin C after intradermal administration is 1-2 days.
During all periods after intradermal administration of Aversect-2 VK, the concentration of the drug in tissues, organs, blood plasma and milk was at the sensitivity level of the method (<0.001 mg / kg).
When administered to dairy cows, the drug is not excreted in milk.
INDICATIONS
Aversect-2 VK is used for the prevention and treatment of hypodermosis, gastrointestinal and pulmonary nematodes of cattle, including a dairy herd, as well as ixodid ticks.
For the prevention of hypodermatosis in the fall at the end of summer, gadflies are treated with all animals: in the northern and central regions - in October-November, in the southern regions - in November-December.
The treatment is carried out when capsules with larvae appear on the back of animals (depending on the region: from late February to mid-April). With an extensive lesion, all animals are treated, with a weak one - only infested ones.
Treatment of cattle against gastrointestinal and pulmonary nematodes is carried out before stalling, in the spring before pasture pasture and according to indications.
APPLICATION
The drug, in compliance with the rules of asepsis and antiseptics, is injected intradermally into the area of ​​the scapula, forearm, back third of the neck or a milk speculum using a needleless mechanical injector BI 7M of the Bumblebee type or BI-7 'Gadfly' in case of hypodermatosis in adult animals and young animals at a dose of 0.1 ml per head, for other invasions at the rate of 0.1 ml for every 100 kg of body weight. To inject the drug, the injector is pressed tightly with the nozzle perpendicular to the skin, the release button is gently pressed, while instant intradermal injection occurs.
At the injection site, a tubercle (pea) with a diameter of about 8 mm is formed, which indicates the correctness of the drug administration.
Do not move the nozzle relative to the injection site at the time of injection to avoid cuts by the jet.
Livestock processing for all invasions is carried out once.
SIDE EFFECTS
When used in the recommended doses, the drug has no side effects.
Slaughter of animals for meat is allowed 1 day after treatment with the agent.
Milk after treatment with the preparation of dairy cows can be used without restrictions.
CONTRAINDICATIONS
The drug is not used for weakened and emaciated animals, as well as for females one month before and after childbirth.
OVERDOSE
With a significant overdose, animals can experience: depression, impaired coordination, recumbency. There are no antidotes.
SHELF LIFE AND STORAGE
Store the drug in the manufacturer's packaging in a dry, dark place at a temperature of -20 В° C to + 30 В° C, separately from food and feed. Expiration date - 3 years from the date of manufacture.
PACKAGING
Aversect-2 VK is produced in the form of a sterile solution, packaged in hermetically sealed 20 ml vials.
Specifications
KolVUP
ten
Manufacturer
Pharmbiomedservice
Temperature regime
from 0 to +30
Teaser
for prophylactic and therapeutic purposes in case of nematodes and arachno-entomoses (hypodermatosis, sarcoptic mange, chorioptosis, psoroptosis, ixodid ticks, syphunculatosis)