Aurobin ointment, 20 g

Processes accompanied by inflammation of the perianal region, itching of the anus, eczema and dermatitis of the perianal region, cracks, hemorrhoids, fistula of the anus.

Outwardly, rectally.
Adults, elderly patients: The
ointment is applied to the affected surface 2-4 times a day.
With internal hemorrhoids, a small amount of ointment (the size of a pea) is injected into the rectum 2-4 times a day. If symptoms decrease, the drug can be used less frequently. The course of treatment is 5-7 days.
Children:
Children under 12 months of age should not use the ointment.
When using the drug in children, long-term use and on a large surface, regardless of age, should be avoided.

Active ingredients:
Prednisolone capronate - 0.002 g,
Lidocaine hydrochloride - 0.020 g;
Dexpanthenol - 0.020 g.
Excipients:
Polysorbate 60, triclosan, methyl parahydroxybenzoate, cetyl alcohol, glycerol, propylene glycol, macrogol stearate, liquid paraffin, dimethicone, neutral oil, stearic acid, purified water.

Hypersensitivity to the components of the drug.
The drug should not be used to treat the eyes or periorbital area.
Bacterial, viral, or fungal skin infections.
Simultaneous use of lidocaine for other indications.
Children up to age 1 year.

Trade name: AurobinЃ

Dosage form:

ointment for rectal and external use

COMPOSITION: 1 g of ointment contains:
Active ingredients:
Prednisolone capronate - 0.002 g,
Lidocaine hydrochloride - 0.020 g;
Dexpanthenol - 0.020 g.
Excipients:
Polysorbate 60, triclosan, methyl parahydroxybenzoate, cetyl alcohol, glycerol, propylene glycol, macrogol stearate, liquid paraffin, dimethicone, neutral oil, stearic acid, purified water.

Description: Homogeneous white or almost white ointment, practically odorless.

Pharmacotherapeutic group:

glucocorticosteroid + antimicrobial agent

ATX code: D07XA02

PHARMACOLOGICAL PROPERTIES
Pharmacodynamics: AurobinЃ is a combined drug for the treatment of inflammatory diseases of the anogenital region.
Prednisolone capronate is a non-halogenated glucocorticosteroid. It has a local anti-allergic and anti-inflammatory effect. The drug reduces vascular permeability, increases the tone of the walls of blood vessels, reduces the symptoms of inflammation.
Lidocaine is a local anesthetic that quickly relieves pain and burning sensation.
Dexpanthenol - promotes the regeneration of the affected epithelium and mucous membrane.
Triclosan is a broad-spectrum antiseptic that acts against bacteria and fungi.
Pharmacokinetics: not studied

INDICATIONS FOR USE
Processes accompanied by inflammation of the perianal region, itching of the anus, eczema and dermatitis of the perianal region, cracks, hemorrhoids, fistula of the anus.

CONTRAINDICATIONS
Hypersensitivity to the components of the drug.
The drug should not be used to treat the eyes or periorbital area.
Bacterial, viral, or fungal skin infections.
Simultaneous use of lidocaine for other indications.
Children up to age 1 year.

Application during pregnancy and lactation
There is insufficient data on the safe use of the drug in pregnant women, therefore, the drug cannot be used in the first trimester of pregnancy. In the second and third trimesters of pregnancy, when prescribing the drug, it is necessary to carefully assess the balance of benefits and risks.
Lactation period:
Corticosteroids and lidocaine pass into breast milk, therefore, during lactation, it is necessary to decide on the termination of breastfeeding.

DOSAGE AND METHOD OF APPLICATION
Externally, rectally.
Adults, elderly patients: The
ointment is applied to the affected surface 2-4 times a day.
With internal hemorrhoids, a small amount of ointment (the size of a pea) is injected into the rectum 2-4 times a day. If symptoms decrease, the drug can be used less frequently. The course of treatment is 5-7 days.
Children:
Children under 12 months of age should not use the ointment.
When using the drug in children, you should avoid long-term use and on a large surface, regardless of age.

SIDE EFFECTS
The use of local glucocorticosteroids can primarily cause local side effects: impairment of wound healing, burning sensation, itching, irritation, dryness, thinning of the skin, increased skin sensitivity.
With prolonged use of glucocorticosteroids - skin atrophy, local hirsutism, telangiectasia, purpura, hypopigmentation, hypertrichosis, folliculitis, acne-like rashes, the development of a fungal infection, allergic contact dermatitis, diaper rash.
When applied to large surfaces - systemic manifestations of side effects of the glucocorticosteroid (growth retardation, Itsenko-Cushing's syndrome, benign increase in intracranial pressure after the end of treatment, hyperglycemia, glucosuria, hypokalemia, increased blood pressure)
With prolonged use and on a large surface due to the systemic action of lidocaine, bradycardia may occur.

OVERDOSE
Acute overdose is unlikely, however, in case of chronic overdose or improper use of the drug, symptoms may occur due to the systemic action of the glucocorticosteroid, as well as bradycardia with excessive administration of the drug into the rectum (due to lidocaine), while it is necessary to stop treatment or gradually reduce the dose.

INTERACTIONS WITH OTHER MEDICINAL PREPARATIONS
When the drug is applied topically, drug interactions are not known.

SPECIAL INSTRUCTIONS
Long-term therapy should be avoided if possible, especially in children, due to the possible suppression of adrenal function. The drug in children can be used with caution, in the minimum dose that ensures the achievement of a therapeutic effect. The duration of therapy in children should not exceed 5 days.
Avoid accidental contact with the eyes or periorbital area.
In case of contact, rinse with water.
The development or spread of a secondary infection requires discontinuation of the drug and the appointment of antimicrobial or antifungal therapy. The bacterial infection is maintained in warm, humid conditions, so the skin must be cleansed before each application of the ointment.
Application to a wide area or use for a long time can lead to systemic absorption of the active ingredients. With prolonged use of the drug in one area, it can cause skin atrophy, especially in young people.

The effect of the drug on the ability to drive a car and working mechanisms
There is no data on the effect of AurobinЃ affects the ability to drive vehicles or work in conditions of increased attention.

FORM OF RELEASE
Ointment for rectal and external use.
20 g of the drug in an aluminum tube. 1 tube with instructions for use in a cardboard box.

SHELF LIFE
2 years.
Do not use after the expiration date.

STORAGE CONDITIONS
List B.
At a temperature from 8 to 15 ? C.
Out of the reach of children.

TERMS OF RELEASE FROM PHARMACIES
By prescription.