Atsetylsalytsylovaya acid | Upsarin Upsa effervescent tablets 500 mg 16 pcs.

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SKU
BID462446
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Latin name

Upsarin UPSA
Latin name

Upsarin UPSA

Release form

Uppsarin Opp. Effervescent tablets.

Packing

In a strip of 4 tablets. There are 4 strips in a cardboard bundle.

Pharmacological action

Non-steroidal anti-inflammatory drug (NSAID).

It has anti-inflammatory, analgesic and antipyretic effects associated with the suppression of cyclooxygenase 1 and 2, which regulates the synthesis of prostaglandins.

Reduces aggregation, platelet adhesion and thrombosis by suppressing the synthesis of thromboxane A 2 in platelets.

Anti-aggregation effect persists for 7 days after a single dose (more pronounced in men than in women).

Dissolving in water, the Uppsarin Upsa tablet forms a buffer solution which, after taking the drug, maintains the active substances in dissolved form, preventing them from coming into contact with the acidic environment of the stomach back into the insoluble form and precipitating as solid particles on its walls.

The result is faster and more complete absorption of the drug, as well as its better tolerance compared to conventional acetylsalicylic acid tablets.

Indications

moderate or mild pain in adults of various origins: headache (including those associated with alcohol withdrawal syndrome), toothache, migraine, neuralgia, chest radicular syndrome, muscle and joint pain, algomenorrhea

fever bodies for colds and other infectious and inflammatory diseases (in adults and children over 15 years old).

Contraindications

Hypersensitivity to acetylsalicylic acid, other NSAIDs and drug components.

Erosive-ulcerative lesions (in the acute phase) of the gastrointestinal tract, gastrointestinal bleeding.

Severe impaired liver or kidney function.

"Aspirin Asthma".

Hemorrhagic diathesis: Hemophilia.

von Willebrand disease.

Teleangiectasia.

Hypoprothrombinemia.

Thrombocytopenia.

Thrombocytopenic purpura.

Exfoliating aortic aneurysm.

Portal hypertension.

Vitamin K deficiency.

Deficiency of glucose-6-phosphate dehydrogenase, phenylketonuria.

Pregnancy (I and III trimester).

Breastfeeding period.

The drug is not prescribed for children under 15 years old with acute respiratory infections caused by viral infections, because of the risk of Reye syndrome (encephalopathy and acute fatty liver disease with acute development of liver failure)

Precautions:

Hyperuricemia.

Urate nephrolithiasis.

Gout.

Peptic ulcer of the stomach and / or duodenum (history).

Uncompensated heart failure.

Use during pregnancy and lactationand during lactation.

Composition

1 tab. contains:

Active ingredients:

acetylsalicylic acid 500 mg

Excipients:

citric acid anhydrous,

sodium carbonate anhydrous,

sodium bicarbonate,

sodium citrate anhydrous,

aspartame, srdlp srdlp







srdlcp

Dosage and administration

The drug is intended for adults and children over 15 years of age.

Take by mouth.

Adults and children over 15 years of age: take 1 tablet (500 mg) up to 6 times a day. For severe pain and high temperature - 2 tablets (1 g), the maximum daily dose should not exceed 6 tablets (3 g).

Elderly: Take 1 tablet (500 mg) up to 4 times a day, the maximum daily dose should not exceed 4 tablets (2 g).

How to use: dissolve the tablet / tablets in a glass (200 ml) of water or juice.

Frequency and time of administration: the interval between doses of the drug should be at least 4 hours.

Regular adherence to the drug allows you to avoid a sharp increase in temperature and reduce the intensity of the pain syndrome.

The duration of treatment (without consulting a doctor) should not exceed 5 days when prescribed as an anesthetic and more than 3 days as an antipyretic.

Side effects of

In recommended doses, the drug is usually well tolerated. In rare cases, the following side effects may occur:

Allergic reactions: skin rash, bronchospasm, Quincke’s edema formation of the “aspirin” triad based on the hapten mechanism (a combination of bronchial asthma, recurring polyposis of the nose and paranasal sinuses, as well as intolerance to acetylsalicylic acid and pyrazolone preparations).

Gastrointestinal disorders: nausea, vomiting, pain. epigastric region, diarrhea (diarrhea), gastrointestinal bleeding (vomiting like "coffee grounds", black "tar-like" stool) decreased appetite, increased activity of "liver" transaminases.

Impaired renal function.

Thrombocytopenia, anemia, leukopenia, hyperbilirubinemia

Hemorrhagic syndrome (nosebleeds, bleeding gums), increased blood clotting time.

If you experience any side effects, you must immediately stop taking the drug and inform your doctor.

Drug Interaction

Acetylsalicylic acid increases the toxicity of methotrexate, the effects of narcotic analgesics, other NSAIDs, oral hypoglycemic drugs, heparin, indirect anticoagulants, thrombolytic agents and inhibitors, thrombolytics, and inhibitors. triiodothyronine decreases - uricosuric drugs (benzbromarone, sulfinpyrazone), antihypertensives and diuretics (spironolactone, furosemide)

Glucocorticosteroids, alcohol and alcohol-containing drugs increase the damaging effect on development

Acetylsalicylic acid increases the concentration of digoxin, barbiturates and lithium preparations in blood plasma. srcdlkp Antacids containing magnesium and / or aluminum hydroxide slow down and impair the absorption of acetylsalicylic acid.

Overdose

Symptoms: Symptoms of CNS arousal, dizziness, severe headache, hearing loss, visual impairment, nausea, vomiting, increased breathing develop in the initial stage of poisoning. Later comes the depression of consciousness down to a coma, respiratory failure, disturbances of water-electrolyte exchange.

Treatment: should induce vomiting or gastric lavage, appoint activated charcoal and laxative. Treatment should be carried out in a specialized department.

Storage conditions

Store in a dry place at a temperature not exceeding 3 РC.

Keep out of the reach of children.

Expiration

3 years.

Deystvuyuschee substances

Atsetylsalytsylovaya acid



pharmacy leave terms without a prescription

Dosage form

dosage form

tablets soluble

Uppsala SAS, France

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