ATP-Vial solution 10mg / ml, 1ml No. 10

ATP-Vial solution 10mg / ml, 1ml No. 10; Muscular dystrophy, myoatrophy, obliterating atherosclerosis of the vessels of the lower extremities, Raynaud's disease, thromboangiitis obliterans, paroxysmal supraventricular tachycardia.

In / m - 1 ml of 1% solution 1-2 times a day. The course of treatment is 30-40 injections. A second course - in 1-2 months. To stop the paroxysm of supraventricular tachycardia, 1-2 ml of a 1% solution is injected intravenously (the effect occurs after 30-40 seconds). Re-introduction - in 2-3 minutes.

1 ml of the drug (1 ampoule) contains:

Sodium adenosine triphosphate disubstituted (in terms of adenosine triphosphate) - 10 mg,

Excipients.

Hypersensitivity to the components of the drug. The drug is not prescribed for patients with acute myocardial infarction. The drug is not used to treat children under the age of 18 years due to the lack of reliable data on the safety and efficacy of the drug in this age category.

pharmachologic effect

A product that improves metabolism and energy supply to tissues. ATP is a natural component of body tissues - it is involved in many metabolic processes. When ATP breaks down into ADP and inorganic phosphate, energy is released, which is necessary for muscle contraction and various biochemical processes. ATP is involved in the transmission of excitation in adrenergic and cholinergic synapses, facilitates the transmission of excitation from the vagus nerve to the heart. Apparently, ATP is one of the mediators that excite adenosine receptors. Strengthens cerebral and coronary circulation, increases peripheral circulation. Triphosadenine is an adenosine derivative. Adenosine is an agonist of purinergic receptors, the activation of which leads to inhibition of depolarization of the processes of conducting electrical impulses in the sinus and AV nodes.This effect underlies the antiarrhythmic action of triphosadenine in supraventricular tachycardia. Acts for a short time within a few seconds.

Side effects

With i / m administration: possible headache, tachycardia, increased urine output, hyperuricemia. With the on / in the introduction: nausea, hyperemia of the skin of the face, headache, weakness are possible. Allergic reactions: rarely - itching, flushing of the skin.

Overdose

At the moment, there have been no reports of drug overdose.