Arbidol caps. 100mg # 10

Dosage form

Capsules

Structure

umifenovir (umifenovir hydrochloride monohydrate (arbidol) in terms of umifenovir hydrochloride) - 100 mg

Excipients:

potato starch, microcrystalline cellulose, colloidal silicon dioxide (aerosil), povidone (kollidon 25), calcium stearate.

pharmachologic effect

Antiviral agent. Specifically inhibits influenza A and B viruses, coronavirus associated with severe acute respiratory syndrome (SARS). According to the mechanism of antiviral action, it belongs to fusion inhibitors (fusion), interacts with the hemagglutinin of the virus and prevents the fusion of the lipid membrane of the virus and cell membranes. It has a moderate immunomodulatory effect. It has interferon-inducing activity, stimulates humoral and cellular immune responses, phagocytic function of macrophages, increases the body's resistance to viral infections. Reduces the incidence of complications associated with a viral infection, as well as exacerbations of chronic bacterial diseases.

Therapeutic efficacy in viral infections is manifested in a decrease in the severity of general intoxication and clinical phenomena, and a reduction in the duration of the disease.

Refers to low-toxic drugs (LD50> 4 g / kg).

Does not have any negative effects on the human body when taken orally in recommended doses.

Pharmacokinetics

It is quickly absorbed and distributed to organs and tissues.

The maximum concentration in blood plasma when taken at a dose of 50 mg is achieved after 1.2 hours, at a dose of 100 mg - after 1.5 hours. It is metabolized in the liver.

The half-life is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in a small amount by the kidneys (0.12%).

During the first day, 90% of the administered dose is removed.

Side effects

Rarely - allergic reactions.

Selling features

Available without a prescription

Special conditions

It does not show central neurotropic activity and can be used in medical practice for prophylactic purposes in practically healthy individuals of various professions, incl.

requiring increased attention and coordination of movements (transport drivers, operators, etc.).

Indications

Prevention and treatment in adults and children:

- influenza A and B, ARVI, severe acute respiratory syndrome (SARS) (including those complicated by bronchitis, pneumonia)

- secondary immunodeficiency states

- complex therapy of chronic bronchitis, pneumonia and recurrent herpes infection.

Prevention of postoperative infectious complications and normalization of the immune status.

Complex therapy of acute intestinal infections of rotavirus etiology in children over 3 years old.

Contraindications

Hypersensitivity to the drug, age up to 3 years

Drug interactions

When administered with other drugs, no negative effects were noted.

Dosage

Inside, before meals.

Single dose: children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg (2 capsules of 100 mg or 4 capsules of 50 mg).

For non-specific prophylaxis:

With direct contact with patients with influenza and other acute respiratory viral infections:

- children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg once a day for 10-14 days.

During an epidemic of influenza and other acute respiratory viral infections, to prevent exacerbations of chronic bronchitis, recurrence of herpes infection:

- children from 3 to 6 years old - 50 mg, from 6 to 12 years old - 100 mg, over 12 years old and adults - 200 mg twice a week for 3 weeks.

For the prevention of SARS (in contact with a patient):

- Adults and children over 12 years old are prescribed 200 mg once a day.

Children from 6 to 12 years old, 100 mg once a day (before meals) for 12-14 days.

Prevention of postoperative complications:

- children from 3 to 6 years old -

Name ENG

ARBIDOL

Clinical and pharmacological group

Antiviral drug

ATX code

Umifenovir

Dosage

100mg

Structure

umifenovir (umifenovir hydrochloride monohydrate (arbidol) in terms of umifenovir hydrochloride) - 100 mg.

Excipients: potato starch, microcrystalline cellulose, colloidal silicon dioxide (aerosil), povidone (kollidone 25), calcium stearate.

Indications

Treatment and prevention of influenza and other acute respiratory infections (including those complicated by bronchitis and pneumonia)

as part of the combination therapy of chronic bronchitis, pneumonia and recurrent herpes infection

as part of the complex therapy of acute intestinal infections of rotavirus etiology in children over 2 years old

prevention of postoperative infectious complications

normalization of the immune status.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Contraindications

Children under 2 years old

- hypersensitivity to the drug.

INN / Active ingredient

umifenovir hydrochloride

Specifications

Category

Antiviral

,

Antimicrobial agents

Scope of the medicinal product

Ear, Throat, Nose

Release form

Capsules

Manufacturer country

Russia

Package quantity, pcs

ten

Way of introduction

Through the mouth

Mode of application

Inside, before meals.

Vacation conditions

Without recipe

Brand name

OTCPharm

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antiviral agent

Anatomical and therapeutic characteristics

J05AX13 Umifenovir

Dosage form

Capsules

Dosage (volume) of the substance in the preparation

1 caps.

- 100 mg

The target audience

Children

Expiration date in days

1095

Package weight, g

ten

Information on technical characteristics, delivery set, country of manufacture