Anhidak spray 255mg / dose, 30 ml (176 doses)

Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiology):

• gingivitis, glossitis, periodontal disease, stomatitis (including after radiation and chemotherapy);

• pharyngitis, laryngitis, tonsillitis;

• oral mucosa candidiasis (as part of combination therapy);

• calculous inflammation of the salivary glands;

• after surgical interventions and injuries (tonsillectomy, jaw fractures);

• after treatment and tooth extraction.

For infectious and inflammatory diseases requiring systemic treatment, it is necessary to use the drug as part of a combination therapy.

Locally, after eating.

One dose (one injection) corresponds to 0.255 mg of benzydamine.

Adults (including elderly patients) and children over 12 years old - 4-8 injections 2-6 times / day.

Children from 6 to 12 years old - 4 injections 2-6 times / day.

Children from 3 to 6 years old - 1 injection for every 4 kg of body weight, but no more than 4 injections (maximum single dose) 2-6 times / day.

A course of treatment

Duration of treatment is 7 days; if after 7 days of treatment there is no improvement, it is necessary to consult a doctor.

Directions for use

1. Rotate the cannula (white tube) to the 'vertical to the vial' position.

2. Insert the cannula into the mouth and aim at the inflamed areas in the mouth and throat.

3. Press the dosage pump on the top of the vial as many times as the prescribed doses. One press corresponds to one dose. Hold your breath while injecting.

Caution: Before first use, press the sprayer into the air several times.

Do not exceed the recommended dose. Before use, the patient should consult a doctor.

1 dose of benzydamine hydrochloride 0.255 mg

Excipients : ethanol 95% - 13.89 mg, glycerin - 8.52 mg, methyl parahydroxybenzoate - 0.17 mg, menthol flavor - 0.051 mg, sodium saccharinate - 0.041 mg, sodium bicarbonate - 0.019 mg, polysorbate 20 - 0.009 mg, 1M sodium hydroxide solution or 0.5 M hydrochloric acid solution - up to pH 5.0-7.0, water d / i - up to 170 ?l.

30 ml (176 doses) - bottles made of high density polyethylene (1) with a pump and a pressure device with a folding cannula - cardboard packs.

• hypersensitivity to benzydamine or other components of the drug;

• children up to age 3 years.

Carefully

Hypersensitivity to acetylsalicylic acid or other NSAIDs, bronchial asthma (including history).

Release form, packaging and composition of AnidakЃ

Spray for topical application dosed in the form of a clear, colorless or slightly yellowish liquid with a characteristic mint odor.

1 dose of benzydamine hydrochloride 0.255 mg

Excipients : ethanol 95% - 13.89 mg, glycerin - 8.52 mg, methyl parahydroxybenzoate - 0.17 mg, menthol flavor - 0.051 mg, sodium saccharinate - 0.041 mg, sodium bicarbonate - 0.019 mg, polysorbate 20 - 0.009 mg, 1M sodium hydroxide solution or 0.5 M hydrochloric acid solution - up to pH 5.0-7.0, water d / i - up to 170 ?l.

30 ml (176 doses) - bottles made of high density polyethylene (1) with a pump and a pressure device with a folding cannula - cardboard packs.

Clinical and pharmacological group: NSAIDs for local use in ENT practice and dentistry

Pharmaco-therapeutic group: NSAIDs

pharmachologic effect

Benzydamine is an NSAID belonging to the indazole group. It has an anti-inflammatory and local anesthetic effect, has an antiseptic effect against a wide range of microorganisms, restores microcirculation. The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of prostaglandin synthesis. Benzydamine has an antibacterial and specific antimicrobial effect due to the rapid penetration of microorganisms through the membranes with subsequent damage to cellular structures, disruption of metabolic processes and cell lysosomes.

Has antifungal activity against Candida albicans. It causes structural modifications of the cell wall of fungi and their metabolic chains, thus interfering with their reproduction, which was the basis for the use of benzydamine in inflammatory processes in the oral cavity, including infectious etiology

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into the inflamed tissues, is found in the blood plasma in an amount insufficient to obtain systemic effects.

Excretion of the drug occurs mainly by the kidneys in the form of inactive metabolites or conjugation products.

Indications of the drug AnidakЃ

Symptomatic therapy of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiology):

• gingivitis, glossitis, periodontal disease, stomatitis (including after radiation and chemotherapy);

• pharyngitis, laryngitis, tonsillitis;

• oral mucosa candidiasis (as part of combination therapy);

• calculous inflammation of the salivary glands;

• after surgical interventions and injuries (tonsillectomy, jaw fractures);

• after treatment and tooth extraction.

For infectious and inflammatory diseases requiring systemic treatment, it is necessary to use the drug as part of a combination therapy.

Dosage regimen

Locally, after eating.

One dose (one injection) corresponds to 0.255 mg of benzydamine.

Adults (including elderly patients) and children over 12 years old - 4-8 injections 2-6 times / day.

Children from 6 to 12 years old - 4 injections 2-6 times / day.

Children from 3 to 6 years old - 1 injection for every 4 kg of body weight, but no more than 4 injections (maximum single dose) 2-6 times / day.

A course of treatment

Duration of treatment is 7 days; if after 7 days of treatment there is no improvement, it is necessary to consult a doctor.

Directions for use

1. Rotate the cannula (white tube) to the 'vertical to the vial' position.

2. Insert the cannula into the mouth and aim at the inflamed areas in the mouth and throat.

3. Press the dosage pump on the top of the vial as many times as the prescribed doses. One press corresponds to one dose. Hold your breath while injecting.

Caution: Before first use, press the sprayer into the air several times.

Do not exceed the recommended dose. Before use, the patient should consult a doctor.

Side effect

Classification of the incidence of side effects according to WHO: very often (? 1/10), often (from? 1/100 to <1/10), infrequently (from? 1/1000 to <1/100), rarely (from? 1 / 10000 to <1/1000), very rare (<1/10000), frequency unknown (cannot be estimated from available data).

In each group, adverse effects are presented in order of decreasing severity.

Local reactions: rarely - dry mouth, burning sensation in the mouth; frequency unknown - feeling of numbness in the mouth.

Allergic reactions: infrequently - photosensitization; rarely - hypersensitivity reactions, skin rash, pruritus; very rarely - angioedema, laryngospasm; frequency unknown - anaphylactic reactions.

If any of the above side effects are aggravated, or any other side effects are noted, you should immediately inform your doctor.

Contraindications for use

• hypersensitivity to benzydamine or other components of the drug;

• children up to age 3 years.

Carefully

Hypersensitivity to acetylsalicylic acid or other NSAIDs, bronchial asthma (including history).

Application during pregnancy and lactation

Should not be used during pregnancy and during breastfeeding.

Application in children

Use in children under 3 years of age is contraindicated.

Use in elderly patients

Allowed for use in elderly patients in accordance with the dosage regimen.

special instructions

When using the drug, hypersensitivity reactions may develop. In this case, it is recommended to stop treatment and consult a doctor to prescribe appropriate therapy.

In a limited number of patients, the presence of sores in the throat and mouth may indicate a more serious pathology. If symptoms persist for more than 3 days, a doctor should be consulted.

The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. The drug should be used with caution in patients with a history of bronchial asthma due to the possibility of developing bronchospasm while taking the drug.

The drug contains parahydroxybenzoates, which can cause allergic reactions.

The drug contains 13.2 mg of ethanol per dose (one injection).

Ethanol content in a single dose:

• for adults (including elderly patients) and children over 12 years old - 52.8-105.6 mg;

• for children from 6 to 12 years old - 52.8 mg;

• for children from 3 to 6 years old - 13.2 mg of ethanol for every 4 kg of body weight, but not more than 52.8 mg (maximum single dose).

Influence on the ability to drive vehicles and mechanisms

Does not affect the ability to drive vehicles and work with mechanisms.

Overdose

Currently, no cases of drug overdose have been reported.

When using the drug in accordance with the instructions for use, an overdose is unlikely.

If the drug is accidentally swallowed, the following symptoms are possible : vomiting, abdominal cramps, anxiety, fear, hallucinations, convulsions, ataxia, fever, tachycardia, respiratory depression.

Treatment: symptomatic; empty the stomach by causing vomiting, or flush the stomach using a gastric tube (under medical supervision); provide medical supervision, supportive therapy and necessary hydration. No antidote known.

Drug interactions

Interaction studies with other drugs have not been conducted.

Storage conditions of the drug Anidak

The drug should be stored out of the reach of children at a temperature not exceeding 25 ? C.

Shelf life of the drug AnidakЃ

Shelf life is 4 years.
Do not use after the expiration date.

Terms of sale

The drug is dispensed without a prescription.