Amoxisan 100ml
DESCRIPTION
Amoxisan is a suspension for injection for the treatment of diseases of bacterial etiology in animals. In appearance, the drug is a suspension from white to light yellow.
COMPOSITION
Amoxisan in 1 ml contains amoxicillin trihydrate - 150 mg as an active ingredient, as well as auxiliary substances: methylparaben - 1 mg, propylparaben - 0.4 mg, sorbitan monooleate - 10.3 mg, aerosil - 4 mg and medium chain triglycerides - up to 1 ml.
PHARMACOLOGICAL PROPERTIES
Amoxisan belongs to the antibacterial drugs of the penicillin series.
Amoxicillin trihydrate, which is part of the drug, is active against gram-positive and gram-negative microorganisms, including Actynomyces spp., Bacillus antracis, Clostridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Listeria monocytogenes, Stapillcopp. , Escherichia coli. Salmonella spp., Fusobacterium spp., Haemophilus spp., Moraxella spp., Pasteurella spp., Proteus mirabilis, Leptospira spp.
The mechanism of the antibacterial action of amoxicillin is to suppress the functional activity of bacterial enzymes trans peptidases involved in the binding of the main component of the cell wall of microorganisms - peptidglycan.
Amoxicillin trihydrate is easily absorbed from the injection site and penetrates into most organs and tissues of the animal. The maximum concentration of the antibiotic in the blood is observed after 1-2 hours and is maintained at a therapeutic level for at least 48 hours after parenteral administration of the drug.
The antibiotic is excreted from the body mainly in an unchanged form, mainly with urine, to a lesser extent with bile, in lactating animals - partly with milk.
Amoxisan, according to the degree of impact on the body, belongs to moderately hazardous substances (hazard class 3 in accordance with GOST 12.1.007-76), in recommended doses it is well tolerated by animals, does not have embryotoxic, teratogenic and hepatotoxic properties.
DOSAGE AND APPLICATION
Amoxisan is prescribed for therapeutic purposes to cattle, sheep, pigs, dogs and cats for infectious diseases of the gastrointestinal tract, respiratory tract, genitourinary system, joints, soft tissues and skin, necrobacteriosis, umbilical infections, atrophic rhinitis, mastitis-metritis syndrome agalactia and other primary and secondary infections of bacterial etiology, the causative agents of which are sensitive to amoxicillin.
Amoxisan is administered to animals subcutaneously or intramuscularly once at a dose of 1 ml per 10 kg of animal weight (15 mg of active substance per 1 kg of animal weight), if necessary, repeat the injection after 48 hours.
Shake the vial with the drug thoroughly before use.
The maximum volume of a medicinal product for administration in one place should not exceed 20 ml for cattle, 5 ml for pigs, sheep, calves. dogs - 2.5 ml and cats - 1 ml.
SPECIAL INSTRUCTIONS
In case of an overdose of the drug in an animal, the following symptoms are possible: refusal to feed, vomiting, impaired coordination of movements.
The peculiarities of the action at the first use of the drug and at its cancellation were not revealed.
Amoxisan is used, as a rule, once.
If it is necessary to re-administer the drug, the 48-hour interval should not be increased, as this may lead to a decrease in therapeutic efficacy.
Amoxisan should not be used concurrently with thiamphenicol, chloramphenicol. antibiotics of the penicillin group, cephalosporins and fluoroquinolones, as well as mixed with other drugs in the same syringe.
Slaughter of animals for meat is allowed no earlier than 28 days after the last application of Amoxisan.
The meat of animals that were forcedly killed before the expiration of the specified period can be used as feed for fur animals.
Milk of dairy animals is allowed to be used for food purposes, not earlier than 96 hours after the last administration of the drug.
Milk obtained earlier than the established date can be used after boiling in animal feed.
CONTRAINDICATIONS
A contraindication to the use of Amoxisan is the animal's hypersensitivity to the components of the drug and antibiotics of the penicillin group, as well as severe violations of the liver and / or kidneys. Do not use the drug in newborn animals, rabbits and guinea pigs.
SIDE EFFECTS
When using Amoxisan in accordance with this instruction, side effects and complications, as a rule, are not observed.
In rare cases, the animal may develop edema at the injection site, which resolves spontaneously within 1-2 days.
With increased individual sensitivity of the animal to antibiotics of the penicillin group and the development of allergic reactions, the use of the drug is stopped and desensitizing therapy is carried out.
SHELF LIFE AND STORAGE
Store the drug in the manufacturer's closed packaging, separately from food and feed, in a dry place protected from direct sunlight at a temperature of 5 В° C to 25 В° C.
The shelf life of Amoxisan, subject to storage conditions in the manufacturer's sealed packaging, is 2 years from the date of production, after opening the bottle - 28 days.
PACKAGING
Amoxisan is produced in dark glass bottles of 100 ml, sealed with rubber stoppers with aluminum caps. Vials of 100 ml are packed individually in cardboard boxes or in group containers complete with instructions for use.
Specifications
KolVUP
ten
Manufacturer
APICENNA
Temperature regime
from +5 to +25
Teaser
for infectious diseases of the gastrointestinal tract, respiratory tract, genitourinary system, joints, soft tissues and skin