ammonium Hlytsyrryzynat | Epigen intimate spray for external use 0.1% 60 ml
Special Price
$52.38
Regular Price
$62.00
In stock
SKU
BID462153
Description
Pharmacotherapeutic group
Antiviral immunostimulating drug.
ATX code
D06BB
Pharmacological properties of
Pharmacodynamics
Active ingredient of the drug Epigen Intim is activated glycyrrhizic acid obtained by extraction from plant material (licorice root).
Activated glycyrrhizic acid has a complex effect, which includes immunostimulating, antiviral, anti-inflammatory, antipruritic and regenerative.
Activated glycyrrhizic acid induces the production of its own interferons. The immunostimulating effect is manifested by an increase in the number and activity of T - lymphocytes, a decrease in the concentration of immunoglobulin G and an increase in the concentration of immunoglobulin A and M.
Activated glycyrrhizic acid has an antiviral effect on various types of DNA and RNA viruses in vitro and in vivo (Varicella Zoster herpes simplex virus type 1 and 2 cytomegalovirus, various types of human papillomavirus, including oncogenic). Activated glycyrrhizic acid interrupts the replication of viruses in the early stages, causes the virion to exit the capsid, thereby preventing its penetration into the cells. Activated glycyrrhizic acid inactivates these viruses in concentrations that are not toxic to normally functioning cells. Mutant strains of viruses that are resistant to acyclovir and iodouridine are also highly sensitive to glycyrrhizic acid, as are non-mutant strains.
The anti-inflammatory activity of activated glycyrrhizic acid is combined with a stimulating effect on humoral and cellular factors of immunity. Activated glycyrrhizic acid significantly inhibits the release of kinins and prostaglandin synthesis by connective tissue cells in the inflammation zone. The regenerating effect is due to improved repair of the skin and mucous membranes.
Pharmacokinetics
When applied topically and topically, activated glycyrrhizic acid is deposited in the lesion. Systemic absorption occurs slowly. The drug is found in the blood in trace amounts.
Pharmacotherapeutic group
Antiviral immunostimulating drug.
ATX code
D06BB
Pharmacological properties of
Pharmacodynamics
Active ingredient of the drug Epigen Intim is activated glycyrrhizic acid obtained by extraction from plant material (licorice root).
Activated glycyrrhizic acid has a complex effect, which includes immunostimulating, antiviral, anti-inflammatory, antipruritic and regenerative.
Activated glycyrrhizic acid induces the production of its own interferons. The immunostimulating effect is manifested by an increase in the number and activity of T - lymphocytes, a decrease in the concentration of immunoglobulin G and an increase in the concentration of immunoglobulin A and M.
Activated glycyrrhizic acid has an antiviral effect on various types of DNA and RNA viruses in vitro and in vivo (Varicella Zoster herpes simplex virus type 1 and 2 cytomegalovirus, various types of human papillomavirus, including oncogenic). Activated glycyrrhizic acid interrupts the replication of viruses in the early stages, causes the virion to exit the capsid, thereby preventing its penetration into the cells. Activated glycyrrhizic acid inactivates these viruses in concentrations that are not toxic to normally functioning cells. Mutant strains of viruses that are resistant to acyclovir and iodouridine are also highly sensitive to glycyrrhizic acid, as are non-mutant strains.
The anti-inflammatory activity of activated glycyrrhizic acid is combined with a stimulating effect on humoral and cellular factors of immunity. Activated glycyrrhizic acid significantly inhibits the release of kinins and prostaglandin synthesis by connective tissue cells in the inflammation zone. The regenerating effect is due to improved repair of the skin and mucous membranes.
Pharmacokinetics
When applied topically and topically, activated glycyrrhizic acid is deposited in the lesion. Systemic absorption occurs slowly. The drug is found in the blood in trace amounts.
Description
Pharmacotherapeutic group
Antiviral immunostimulating drug.
ATX code
D06BB
Pharmacological properties of
Pharmacodynamics
Active ingredient of the drug Epigen Intim is activated glycyrrhizic acid obtained by extraction from plant material (licorice root).
Activated glycyrrhizic acid has a complex effect, which includes immunostimulating, antiviral, anti-inflammatory, antipruritic and regenerative.
Activated glycyrrhizic acid induces the production of its own interferons. The immunostimulating effect is manifested by an increase in the number and activity of T - lymphocytes, a decrease in the concentration of immunoglobulin G and an increase in the concentration of immunoglobulin A and M.
Activated glycyrrhizic acid has an antiviral effect on various types of DNA and RNA viruses in vitro and in vivo (Varicella Zoster herpes simplex virus type 1 and 2 cytomegalovirus, various types of human papillomavirus, including oncogenic). Activated glycyrrhizic acid interrupts the replication of viruses in the early stages, causes the virion to exit the capsid, thereby preventing its penetration into the cells. Activated glycyrrhizic acid inactivates these viruses in concentrations that are not toxic to normally functioning cells. Mutant strains of viruses that are resistant to acyclovir and iodouridine are also highly sensitive to glycyrrhizic acid, as are non-mutant strains.
The anti-inflammatory activity of activated glycyrrhizic acid is combined with a stimulating effect on humoral and cellular factors of immunity. Activated glycyrrhizic acid significantly inhibits the release of kinins and prostaglandin synthesis by connective tissue cells in the inflammation zone. The regenerating effect is due to improved repair of the skin and mucous membranes.
Pharmacokinetics
When applied topically and topically, activated glycyrrhizic acid is deposited in the lesion. Systemic absorption occurs slowly. The drug is found in the blood in trace amounts.
Release form
Spray for external and local use.
Packaging
In a plastic bottle with a dispenser of 60 ml of the product.
In the package 1 bottle with a spray nozzle for intravaginal use.
Contraindications
Hypersensitivity to the components of the drug.
Directions for use
Topically, intravaginally and intraurethrally.
Shake the bottle before use. When using the cylinder, keep it upright.
For external use, the drug is applied to the entire affected surface of the skin from a distance of 4-5 cm by 1-2 valve presses, which is the optimal therapeutic dose.
For intravaginal use of the drug, a special nozzle with a spray is attached. Remove the valve from the spray bottle and put on the nozzle valve. Then, insert the nozzle into the vagina and inject it by 1-2 pressing the nozzle, which is the optimal therapeutic dose.
When used by men, in addition to external application, the drug is injected into the external opening of the urethra with 1-2 presses of the pulverizing valvecongestion.
In case of herpesvirus infection type I, shingles, the drug is recommended to be used 6 times a day for the lesion for 5 days. With a stubborn course of the infectious process, the treatment period is extended until the symptoms of the disease completely disappear.
In case of herpesvirus infection type II (genital herpes), cytomegalovirus infection is recommended to be applied 5 times a day for 14 days externally and intravaginally, after relief of relapse - externally and intravaginally 3 times a day for 10 days.
In order to prevent recurrence of genital herpes and cytomegalovirus infection, the drug is recommended to be applied topically and intravaginally from 18-20 days of the menstrual cycle until the end of menstruation 2 times a day in the morning and evening.
In case of human papillomavirus infection, the drug is recommended for use:
before removal of genital warts - 3 times a day during the entire period of etiotropic therapy.
against the background of destruction - 5 times a day for 10 days or more until complete healing.
for prophylaxis of the next relapse 3 times a day for 1 month.
To prevent the progression of papillomavirus infection, it is recommended to use it before and after sexual intercourse, as well as when provoking factors (stress, overwork, respiratory viral infections, microflora disturbance, taking antibiotics, cytostatics) - 3 times a day intravaginally and externally throughout the period exposure to provoking factors.
For bacterial vaginosis, nonspecific vulvovaginitis, and candidal vulvovaginitis: the drug is recommended to be administered intravaginally 3-4 times a day for 7-10 days. If necessary, repeat the treatment after 10 days. In case of provoking factors (respiratory viral infections, taking antibiotics, cytostatics) - 3 times a day intravaginally and externally during the entire period of exposure to provoking factors.
In cases of discomfort in the genital area, accompanied by itching, burning and dry mucous membranes: 2 times a day (morning and evening) for 2-3 weeks. In order to prevent discomfort, apply regularly after intercourse.
As a prophylactic antiviral agent, the drug is recommended to be used before and after sexual intercourse.
Special instructions
The nozzle is washed with boiled water and soap and stored in the attached plastic bag. The design of the nozzle allows you to evenly irrigate the cervix and the walls of the vagina.
When used in a hospital environment, intravaginal irrigation of drugs in the mirrors can be carried out without a nozzle.
For effective action prior to use of the drug does not require preliminary washing of the affected area.
If signs of intolerance appear, use of the drug should be discontinued.
Possible individual intolerance to the components of the drug.
In rare cases, local allergic reactions are possible, including in the form of contact dermatitis.
No interaction with the main groups of drugs used for the complex treatment of viral diseases (analgesics and antiseptics, anti-inflammatory and analgesics).
Synergy was found with the simultaneous use of glycyrrhizic acid and other antiviral drugs, in particular derivatives of acyclovir, yo
The drug is approved for use during the entire period of pregnancy and lactation.
of douridine, interferon, and other immunomodulators.
Composition
Composition per 100 ml of the preparation:
Active ingredient:
glycyrrhizic acid activated (equivalent to ammonium glycyrrhizinate) 0.1 g
Excipients:
malic acid,
fumaric acid, srdlk acid, srdlkk acid
propylene glycol,
twin - 80 (polysorbate - 80),
purified water.
Description.
Light yellow to light brown solution with a characteristic odor.
Storage conditions
At a temperature of 15 ° to 30 РC, out of the reach of children.
Shelf life
3 years. Do not use after expiration date.
Active substance
Ammonium Glycyrrhizinate
type kozhy
to vseh typical
release form
Spray
B.Braun Medical SA, Spain
Pharmacotherapeutic group
Antiviral immunostimulating drug.
ATX code
D06BB
Pharmacological properties of
Pharmacodynamics
Active ingredient of the drug Epigen Intim is activated glycyrrhizic acid obtained by extraction from plant material (licorice root).
Activated glycyrrhizic acid has a complex effect, which includes immunostimulating, antiviral, anti-inflammatory, antipruritic and regenerative.
Activated glycyrrhizic acid induces the production of its own interferons. The immunostimulating effect is manifested by an increase in the number and activity of T - lymphocytes, a decrease in the concentration of immunoglobulin G and an increase in the concentration of immunoglobulin A and M.
Activated glycyrrhizic acid has an antiviral effect on various types of DNA and RNA viruses in vitro and in vivo (Varicella Zoster herpes simplex virus type 1 and 2 cytomegalovirus, various types of human papillomavirus, including oncogenic). Activated glycyrrhizic acid interrupts the replication of viruses in the early stages, causes the virion to exit the capsid, thereby preventing its penetration into the cells. Activated glycyrrhizic acid inactivates these viruses in concentrations that are not toxic to normally functioning cells. Mutant strains of viruses that are resistant to acyclovir and iodouridine are also highly sensitive to glycyrrhizic acid, as are non-mutant strains.
The anti-inflammatory activity of activated glycyrrhizic acid is combined with a stimulating effect on humoral and cellular factors of immunity. Activated glycyrrhizic acid significantly inhibits the release of kinins and prostaglandin synthesis by connective tissue cells in the inflammation zone. The regenerating effect is due to improved repair of the skin and mucous membranes.
Pharmacokinetics
When applied topically and topically, activated glycyrrhizic acid is deposited in the lesion. Systemic absorption occurs slowly. The drug is found in the blood in trace amounts.
Release form
Spray for external and local use.
Packaging
In a plastic bottle with a dispenser of 60 ml of the product.
In the package 1 bottle with a spray nozzle for intravaginal use.
Contraindications
Hypersensitivity to the components of the drug.
Directions for use
Topically, intravaginally and intraurethrally.
Shake the bottle before use. When using the cylinder, keep it upright.
For external use, the drug is applied to the entire affected surface of the skin from a distance of 4-5 cm by 1-2 valve presses, which is the optimal therapeutic dose.
For intravaginal use of the drug, a special nozzle with a spray is attached. Remove the valve from the spray bottle and put on the nozzle valve. Then, insert the nozzle into the vagina and inject it by 1-2 pressing the nozzle, which is the optimal therapeutic dose.
When used by men, in addition to external application, the drug is injected into the external opening of the urethra with 1-2 presses of the pulverizing valvecongestion.
In case of herpesvirus infection type I, shingles, the drug is recommended to be used 6 times a day for the lesion for 5 days. With a stubborn course of the infectious process, the treatment period is extended until the symptoms of the disease completely disappear.
In case of herpesvirus infection type II (genital herpes), cytomegalovirus infection is recommended to be applied 5 times a day for 14 days externally and intravaginally, after relief of relapse - externally and intravaginally 3 times a day for 10 days.
In order to prevent recurrence of genital herpes and cytomegalovirus infection, the drug is recommended to be applied topically and intravaginally from 18-20 days of the menstrual cycle until the end of menstruation 2 times a day in the morning and evening.
In case of human papillomavirus infection, the drug is recommended for use:
before removal of genital warts - 3 times a day during the entire period of etiotropic therapy.
against the background of destruction - 5 times a day for 10 days or more until complete healing.
for prophylaxis of the next relapse 3 times a day for 1 month.
To prevent the progression of papillomavirus infection, it is recommended to use it before and after sexual intercourse, as well as when provoking factors (stress, overwork, respiratory viral infections, microflora disturbance, taking antibiotics, cytostatics) - 3 times a day intravaginally and externally throughout the period exposure to provoking factors.
For bacterial vaginosis, nonspecific vulvovaginitis, and candidal vulvovaginitis: the drug is recommended to be administered intravaginally 3-4 times a day for 7-10 days. If necessary, repeat the treatment after 10 days. In case of provoking factors (respiratory viral infections, taking antibiotics, cytostatics) - 3 times a day intravaginally and externally during the entire period of exposure to provoking factors.
In cases of discomfort in the genital area, accompanied by itching, burning and dry mucous membranes: 2 times a day (morning and evening) for 2-3 weeks. In order to prevent discomfort, apply regularly after intercourse.
As a prophylactic antiviral agent, the drug is recommended to be used before and after sexual intercourse.
Special instructions
The nozzle is washed with boiled water and soap and stored in the attached plastic bag. The design of the nozzle allows you to evenly irrigate the cervix and the walls of the vagina.
When used in a hospital environment, intravaginal irrigation of drugs in the mirrors can be carried out without a nozzle.
For effective action prior to use of the drug does not require preliminary washing of the affected area.
If signs of intolerance appear, use of the drug should be discontinued.
Possible individual intolerance to the components of the drug.
In rare cases, local allergic reactions are possible, including in the form of contact dermatitis.
No interaction with the main groups of drugs used for the complex treatment of viral diseases (analgesics and antiseptics, anti-inflammatory and analgesics).
Synergy was found with the simultaneous use of glycyrrhizic acid and other antiviral drugs, in particular derivatives of acyclovir, yo
The drug is approved for use during the entire period of pregnancy and lactation.
of douridine, interferon, and other immunomodulators.
Composition
Composition per 100 ml of the preparation:
Active ingredient:
glycyrrhizic acid activated (equivalent to ammonium glycyrrhizinate) 0.1 g
Excipients:
malic acid,
fumaric acid, srdlk acid, srdlkk acid
propylene glycol,
twin - 80 (polysorbate - 80),
purified water.
Description.
Light yellow to light brown solution with a characteristic odor.
Storage conditions
At a temperature of 15 ° to 30 РC, out of the reach of children.
Shelf life
3 years. Do not use after expiration date.
Active substance
Ammonium Glycyrrhizinate
type kozhy
to vseh typical
release form
Spray
B.Braun Medical SA, Spain
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