amlodipine | Norvask tablets 5 mg, 14 pcs.

Special Price $17.46 Regular Price $26.00
In stock
SKU
BID462426
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Release form

Tablets.
Release form

Tablets.

Packing

14 pcs.

Pharmacological action

Antianginal, antihypertensive. Norvask blocks the flow of calcium ions through membranes into the smooth muscle cells of the myocardium and blood vessels (calcium channels). Vasodilation leads to a decrease in blood pressure. The antianginal effect is due to both a decrease in O2 consumption due to the expansion of arterioles and a decrease in OPSS (afterload), and an increase in O2 delivery due to dilatation of the main coronary arteries and arterioles in ischemic and unchanged myocardial zones.

Contraindications

Hypersensitivity (including to other dihydropyridines).

Pregnancy and lactation

Not recommended.

Special instructions

Norvask is used with caution in case of renal failure, impaired liver function. Do not prescribe to children (no experience with use).

Composition

1 tablet contains amlodipine (as besilate) 5 mg.

Dosage and administration of

Norvask is taken orally. With arterial hypertension and angina pectoris, the initial dose is 5 mg once a day. It is possible to increase it to a maximum dose of 10 mg, depending on the individual response of the patient.

Side effects

Headache, swelling, fatigue, drowsiness, nausea, abdominal pain, flushing, palpitations and dizziness less often - dyspepsia, arthralgia, asthenia, shortness of breath, gingival hyperplasia, gynecomastia, impotence, increased frequency of urination, mood changes, muscle cramps, myalgia, skin itching, rashes, visual disturbances rarely - erythema multiforme, jaundice and an increase in hepatic transaminases.

Overdose

Symptoms: a marked decrease in blood pressure with the possible development of reflex tachycardia and excessive peripheral vasodilation (there is the possibility of severe and persistent arterial hypotension, including with the development of shock and death).

Treatment: administration of activated charcoal (especially in the first 2 hours after an overdose), gastric lavage (in some cases), elevating the limbs, actively maintaining the function of the cardiovascular system, monitoring heart and lung function, monitoring the volume of circulating blood and diuresis.

To restore vascular tone and blood pressure, if there are no contraindications, it may be useful to use vasoconstrictor drugs. Intravenous administration of calcium gluconate is used. Since amlodipine largely binds to serum proteins, hemodialysis is not effective.

Storage Conditions

In a dark place at a temperature not exceeding 20 РC.

Deystvuyuschee substances

amlodipine

Form of Treatment

tablets

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