Amizon tablets 250mg, No. 20

Inside after meals, without chewing, 0.5 g 3 times / day. The maximum single dose is 1 g, the daily dose is 2 g. The recommended course of treatment is from 5 to 7 days.

Film-coated tablets of yellow or yellow-green color, round, biconvex; the presence of minor inclusions is allowed on the surface.

1 tab. enisamia iodide 250 mg

Excipients: lactose monohydrate (200) - 11 mg, microcrystalline cellulose 101 - 21 mg, povidone K17 - 9 mg, croscarmellose sodium - 6 mg, calcium stearate - 3 mg, Opadry II 85F Clear - 10 mg (polyethylene glycol - 1.5 mg, polysorbate 80 - 0.3 mg, polyvinyl alcohol - 5.2 mg, talc - 3 mg).

• Hypersensitivity to any component of the drug.

• Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.

• Children under 18 years of age, pregnancy, lactation.

pharmachologic effect

AmizonЃ is an antiviral agent derived from isonicotinic acid. Effectively suppresses the action of influenza viruses and other pathogens of acute respiratory viral infections due to the direct (inhibitory) effect on the process of penetration of viruses through the cell membrane. It has interferonogenic properties, increases the concentration of endogenous interferon (interferon alpha and interferon gamma) in blood plasma by 3-4 times. Increases the body's resistance to viral infections. Reduces acute clinical manifestations of viral intoxication, helps to reduce the duration of the disease.

Pharmacokinetics

After oral administration, methylbenzylcarbamidopyridinium iodide quickly enters the bloodstream, Cmax of methylbenzylcarbamidopyridinium iodide is observed after 2-2.5 hours. T1 / 2 is 13.5-14 hours, metabolized in the liver, but rapidly excreted from tissues (half-life is 2-3 hours). It is excreted from the body by 90-95% through the kidneys with urine in the form of metabolites.

Side effect

Bitterness in the mouth, heartburn, burning sensation in the throat, slight swelling of the oral mucosa, which does not require additional treatment or discontinuation of the drug. The drug is well tolerated, according to clinical studies, the frequency of adverse reactions is 6%.

Application during pregnancy and lactation

Not recommended for use during pregnancy and lactation.

Application in children

Contraindicated: children under 18 years of age.

special instructions

Taking AmizonЃ does not affect the ability to drive vehicles and various mechanical equipment.

Overdose

In case of an overdose of the drug, it is possible to increase the side effects described in the corresponding section. When they appear, gastric lavage and symptomatic treatment are performed.

Drug interactions

Interaction with other drugs has not been sufficiently studied.