amino acids for parenteral POWER | Nutriflex 70/180 lipid containers, building, 1.875 l, 5 pcs.

Release form

Emulsion for infusion

Packing

Container 1875 ml.

Pharmacological action

Nutriflex 70/180 lipid supplies the body with a protein synthesis substrate and energy through glucose during parenteral nutrition. Amino acids enter the intravascular and intracellular depots of endogenous free amino acids to maintain homeostasis. Dextrose is involved in various metabolic processes in the body, enhances redox processes in the body, and improves the antitoxic function of the liver. Entering the tissue, phosphorylates, turning into glucose-6-phosphate, which is involved in many parts of the body's metabolism.

Contraindications

Disorders amino acid metabolism

Disorders of lipid metabolism

hyperkalemia, hypernatremia

Severe metabolic disorders (ketoacidosis, coma unknown etiology)

Expressed hyperglycemia, nekorrigiruemaya doses of insulin to 6 units / hour

Acidosis

Intrahepatic cholestasis

Severe hepatic and renal failure

Severe heart failure

Hemorrhagic diathesis

Acute myocardial infarction

Рћ severe cases of thromboembolism,

fat embolism Identified hypersensitivity to egg or soy protein, peanut butter or any of

excipients General contraindications for parenteral nutrition: Heavy circulatory disorders (collapse and shock)

Expressed tissue hypoxia

overhydration Standing

disruption of water-electrolyte balance

acute pulmonary edema, decompensated cardiac failure

Composition

Isoleucine, Leucine, Lysine Hydrochloride, Methionine, Phenylalanine, Threonine, Tryptophan, Valine, Arginine Monoglutamate, Histidine Hydrochloride Monohydrate, Alanine, Aspartic Acid, Medium Glycine, Triglycerides, Glycine, Proglycine, Prolins magnesium acetate tetrahydrate, sodium acetate trihydrate, sodium dihydrogen phosphate dihydrate, potassium acetate, sodium hydroxide, glucose monohydrate, sodium chloride, calcium chloride dihydrate, zinc acetate, electrolytes: sodium, potassium, calcium, magnesium, zinc, chloride, phosphate, acetate.

Dosage and administration

Intended for intravenous administration in peripheral and central veins.

The temperature of the emulsion to be introduced should be at room temperature.

The configuration of Nutriflex lipid chambers allows fat emulsion to be added last, in order to preliminarily evaluate the compatibility with other added drugs.

Method of mixing the contents of the chambers of the

container If you need to add other drugs to the Nutriflex lipid preparation, use the following method: Remove the secondary plastic bag from the container, unfold and lay the container on a firm, level surface (on the table)

Pressing the upper left chamber of the container with both hands ( containing glucose solution with electrolytes), destroy the septum separating it from the lower chamber (containing amino acid solution with electrolytes)

If necessary, add electrolytes trace elements and other compatible medications (including water-soluble vitamins) through an additional port with a red protective cap

With two hands pressing on the upper right chamber of the container (containing fat emulsion), destroy the septum separating it from the lower chamber

Add fat-soluble vitamins if necessary optional port with red

protective cap Gently mix the contents of all container chambers.

If there is no need to add other drugs to Nutriflex lipid, use the following procedure: Remove the secondary plastic bag from the container, unfold and place the container on a firm, level surface (on the table)

Pressing the two upper chambers of the container with both hands, destroy the partitions, separating them from the bottom

camera Gently mix the contents of all the cameras in the container.

To carry out the infusion after mixing the contents of the container chambers: After moving the emulsion to the lower chamber, fold the container along the midline separating the empty upper chambers from the lower

Hang the container on the infusion stand by the special ring in the center of the container

Remove the white protective cap from the infusion port, connect system for intravenous infusion and start infusion at the rate specified in these instructions for use.

Doses:

are selected according to individual needs.

Children over 14 years of age and adults

The maximum daily dose is 40 ml / kg body weight, which corresponds to

1.28 g of amino acids / kg body weight / ki,

2.56 g of glucose / kg body weight / ki,

1. 6 g fat / kg body weight / ki.

Children 2 to 14 years old

These recommendations are based on average needs. The dose should be individually adapted depending on the age, stage of development and severity of the disease. To calculate the dose, the degree of hydration of pediatric patients must be taken into account.

For children, it may be necessary to start nutritional therapy with half the estimated dose. The dose should be increased to the maximum stepwise in accordance with the individual metabolic capabilities of the body.

For children from 2 to 5 years old, the daily dose is 45 ml / kg body weight, which corresponds to

1.44 g amino acids / kg body weight / ki,

2.88 g glucose / kg body weight / ki,

1.8 g fat / kg body weight / ki.

For children from 5 to 14 years old, the daily dose is 30 ml / kg body weight, which corresponds to

0. 96 g amino acids / kg body weight / ki,

1.92 g glucose / kg body weight / ki,

1.20 g fat / kg body weight / ki.

Due to the age-related characteristics of children, Nutriflex lipid may not fully satisfy the energy requirement. In these cases, a glucose solution or a fat emulsion may be added to the parenteral nutrition program as necessary.

Speed ​​of administration

Long-term administration of Nutriflex lipid is recommended. A stepwise increase in the infusion rate during the first 30 minutes reduces the incidence of possible complications.

The maximum infusion rate is 2.5 ml / kg body weight / h, which corresponds to

0.08 g amino acids / kg body weight / h,

0.16 g glucose / kg body weight / h,

0.1 g fat / kg body weight / h.

For a patient weighing 70 kg, the maximum infusion rate will be 175 ml / h. In this case, the rate of introduction of amino acids will be 5.6 g / h, glucose - 11.2 g / h, fat - 7. g / h.

Elderly patients

Doses do not differ from those recommended for other adult patients. However, metabolism can vary significantly in old age, so careful monitoring of this group of patients is necessary.

Patients with renal and / or liver failure

Doses are selected individually.

Duration of use of

Administration of the drug Nutriflex lipid is not recommended for more than seven days.

Storage conditions

In the dark place at a temperature of no higher than 25 РC.

Shelf life

2 years

Active ingredient

Amino acids for parenteral nutrition

lekarstvennaja form

Solution for infusion

B.Grown1954325432f32323232 Braun Melzungen AG, Germany