Aminalon tablets p / o 250mg, No. 100

• Conditions after suffering cerebrovascular accidents; after traumatic brain injury.

• Atherosclerosis of cerebral vessels with symptoms of brain softening.

• Alcoholic encephalopathy and polyneuritis.

• Headache, dizziness, sleep disturbances in arterial hypertension.

• Cerebral palsy; consequences of traumatic brain birth injury in children over 3 years old; mental retardation in children. Kinetoses.

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

The daily dose for adults is 3-3.75 g. Children aged 1 to 3 years - 1-2 g / day; from 4 to 6 years old - 2-3 g / day; over 7 years old - 3 g / day. The daily dose for children and adults is divided into 3 doses and taken before meals. The course of treatment lasts from 2-3 weeks to 2-4 months.

For the prevention and treatment of kinetosis, adults - 500 mg 3 times / day for 3-4 days, children - 250 mg 3 times / day for 3-4 days.

1 tablet of the drug contains

active substance : gamma-aminobutyric acid - 250 mg,

excipients : sucrose (white sugar) - 27,200 mg, magnesium stearate - 2,800 mg,

shell : opadry 200 white (polyvinyl alcohol - 4.900 mg, titanium dioxide - 3.500 mg, macrogol (polyethylene glycol) - 1.680 mg, talc - 3.343 mg, methacrylic acid copolymer type C - 0.560 mg, sodium bicarbonate - 0.017 mg) - 14,000 mg.

Hypersensitivity to drug components

children under 3 years old

acute renal failure

sucrase / isomaltase deficiency

fructose intolerance

glucose-galactose malabsorption of celiac disease.

Carefully:

Contraindicated in the 1st trimester of pregnancy and lactation. Application in the II and III trimester of pregnancy is possible as directed by the attending physician.

Clinical and pharmacological group: Nootropic drug

Pharmaco-therapeutic group: Nootropic agent

pharmachologic effect

Gamma-aminobutyric acid (GABA, gamma-aminobutyric acid) is a biogenic amine, restores metabolic processes in the brain, promotes the utilization of glucose by the brain and the removal of toxic metabolic products from it, and normalizes the dynamics of nervous processes in the brain. Increases the productivity of thinking, improves memory, has a mild psychostimulating effect, has a beneficial effect on the restoration of movements and speech after cerebrovascular accident. It helps to reduce and stabilize high blood pressure and reduce the subjective symptoms of hypertension (dizziness, sleep disturbance).

It has a moderate antihypoxic and anticonvulsant effect. In patients with diabetes mellitus, it reduces the glucose content, with a normal blood glucose content, it has the opposite effect (due to glycogenolysis).

Pharmacokinetics

Absorption is fast, quite complete. Cmax in blood plasma is reached after 60 minutes, then the concentration decreases rapidly. After 24 hours, GABA is not detected in blood plasma.

Indications

• Conditions after suffering cerebrovascular accidents; after traumatic brain injury.

• Atherosclerosis of cerebral vessels with symptoms of brain softening.

• Alcoholic encephalopathy and polyneuritis.

• Headache, dizziness, sleep disturbances in arterial hypertension.

• Cerebral palsy; consequences of traumatic brain birth injury in children over 3 years old; mental retardation in children. Kinetoses.

Dosage regimen

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

The daily dose for adults is 3-3.75 g. Children aged 1 to 3 years - 1-2 g / day; from 4 to 6 years old - 2-3 g / day; over 7 years old - 3 g / day. The daily dose for children and adults is divided into 3 doses and taken before meals. The course of treatment lasts from 2-3 weeks to 2-4 months.

For the prevention and treatment of kinetosis, adults - 500 mg 3 times / day for 3-4 days, children - 250 mg 3 times / day for 3-4 days.

Side effect

Possible: nausea, vomiting, blood pressure lability, dyspepsia, fever, sleep disturbance.

Contraindications for use

Hypersensitivity to drug components

children under 3 years old

acute renal failure

sucrase / isomaltase deficiency

fructose intolerance

glucose-galactose malabsorption of celiac disease.

Carefully:

Contraindicated in the 1st trimester of pregnancy and lactation. Application in the II and III trimester of pregnancy is possible as directed by the attending physician.

Application during pregnancy and lactation

Use is contraindicated in the first trimester of pregnancy and during breastfeeding.

The doctor decides the possibility of use in the II and III trimesters of pregnancy individually.

Application in children

Application is possible according to the dosage regimen.

Use in elderly patients

Application is possible according to the dosage regimen.

special instructions

In the first days of treatment, fluctuations in blood pressure are possible.

Drug interactions

With simultaneous use, it is possible to enhance the effect of benzodiazepine derivatives, many hypnotics and antiepileptic drugs.