Almagel suspension. for oral administration fl 170ml (complete with a measuring spoon) # 1

Release form, composition and packaging

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Suspension for oral administration is white or almost white, with a characteristic lemon odor

during storage, a layer of a transparent liquid may form on the surface with vigorous shaking of the bottle, the homogeneity of the suspension is restored.

5 ml (1 measuring spoon)

algeldrat (aluminum hydroxide gel) 2.18 g,

which corresponds to the content of aluminum oxide 218 mg

magnesium hydroxide paste 350 mg,

which corresponds to the content of magnesium oxide 75 mg

sorbitol - 801.15 mg, hyetellose - 10.9 mg, methyl parahydroxybenzoate - 10.9 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.363 mg, sodium saccharinate dihydrate - 818 μg, lemon oil - 1.635 mg, purified ethanol 96% - 98.1 mg, purified water ml.

170 ml - bottles (1) complete with a dosing spoon (5 ml) - cardboard packs.

pharmachologic effect

Antacid preparation, which is a balanced combination of algeldrate (aluminum hydroxide) and magnesium hydroxide. It neutralizes free hydrochloric acid in the stomach, reduces the activity of pepsin, which leads to a decrease in the digestive activity of gastric juice. It has an enveloping, adsorbing effect. Protects the gastric mucosa by stimulating the synthesis of prostaglandins (cytoprotective effect). Protects the mucous membrane from inflammatory and erosive-hemorrhagic lesions as a result of the use of irritating and ulcerogenic agents such as ethanol, NSAIDs (for example, indomethacin, diclofenac, acetylsalicylic acid), corticosteroids. The therapeutic effect after taking the drug occurs in 3-5 minutes. The duration of action depends on the rate of gastric emptying.When taken on an empty stomach, the effect lasts up to 60 minutes. When taken one hour after a meal, the antacid effect can last up to 3 hours. Does not cause secondary hypersecretion of gastric juice.

Pharmacokinetics

Algeldrat A small amount of the drug is absorbed, which practically does not change the concentration of aluminum salts in the blood.

It is excreted through the intestines.

Magnesium hydroxide Magnesium ions are absorbed in insignificant amounts (about 10% of the dose taken) and do not change the concentration of magnesium in the blood.

It is usually distributed locally.

Magnesium hydroxide is excreted through the intestines.

Indications for use

Treatment - acute gastritis - chronic gastritis with increased and normal gastric secretory function (in the acute phase) - acute duodenitis, enteritis, colitis - peptic ulcer of the stomach and duodenum (in the acute phase) - hernia of the esophageal opening of the diaphragm - gastroesophageal reflux, reflux esophagitis, duodenogastric reflux - symptomatic gastrointestinal ulcers of various origins - erosion of the mucous membrane of the upper gastrointestinal tract - acute pancreatitis, exacerbation of chronic pancreatitis - heartburn and epigastric pain after errors in nutrition, excessive consumption of ethanol, nicotine, coffee, taking medications that irritate the gastric mucosa. Prevention - reduction of irritating and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.

Contraindications for use

- severe renal failure (due to the danger of hypermagnesemia and aluminum intoxication)

- Alzheimer's disease

- hypophosphatemia

- pregnancy

- children under 10 years of age

- congenital fructose intolerance (the drug contains sorbitol)

- hypersensitivity to active substances and auxiliary components of the drug.

Dosage regimen

The drug is taken orally.

Before each dose, the suspension must be thoroughly homogenized by shaking the bottle.

Treatment The drug is taken 45-60 minutes after meals and in the evening before bedtime.

Adults and children over 15 years of age are prescribed 5-10 ml (1-2 scoops) 3-4 times / day.

P

Name ENG

ALMAGEL

Clinical and pharmacological group

Antacid drug

ATX code

Antacids, other combinations

Dosage

218mg / 5ml + 75mg / 5ml x 170ml

Structure

5 ml (one scoop) of the suspension contains: Active ingredients: Aluminum hydroxide gel -2.18 g.

in terms of Al2O3 -218 mg.

Magnesium hydroxide infusion - 350 mg.

in terms of MgO - 75 mg.

Excipients: Hydrogen peroxide solution 30% - 0.41 mg, sorbitol - 801.15 mg, hyetellose - 10.90 mg, methyl parahydroxybenzoate - 10.90 mg, propyl parahydroxybenzoate - 1.363 mg, butyl parahydroxybenzoate - 1.363 mg, sodium saccharinate dihydrate - 0.818 mg , propylene glycol - 327.00 mg, macrogol 4000 - 218.00 mg, lemon oil - 1.635 mg, ethanol 96% - 98.10 mg, purified water up to 5 ml.

Indications

Acute gastritis

chronic gastritis with increased and normal gastric secretory function (in the acute phase)

acute duodenitis, enteritis, colitis

peptic ulcer of the stomach and duodenum (in the acute phase)

hernia of the esophageal opening of the diaphragm

gastroesophageal reflux, reflux esophagitis, duodenogastric reflux

symptomatic gastrointestinal ulcers of various origins

erosion of the mucous membrane of the upper gastrointestinal tract

acute pancreatitis, exacerbation of chronic pancreatitis

heartburn and epigastric pain after errors in nutrition, excessive use of ethanol, nicotine, coffee, taking medications that irritate the gastric mucosa.

Prevention

reduction of irritating and ulcerogenic effects associated with taking medications that irritate the gastric mucosa.

Storage conditions and periods

At a temperature not higher than 25 degrees.

(do not freeze).

Expiration date: 2 years

Contraindications

severe renal failure (due to the risk of developing hypermagnesemia and aluminum intoxication)

Alzheimer's disease

hypophosphatemia

pregnancy

children under 10 years old

congenital fructose intolerance (the drug contains sorbitol)

hypersensitivity to active substances and auxiliary components of the drug.

INN / Active ingredient

Magnesium hydroxide + algeldrate

Specifications

Category

Ulcer and gastritis

,

Antacids

Scope of the drug

Gastrointestinal tract

Release form

Oral suspension

Manufacturer country

Bulgaria

Package quantity, pcs

one

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Almagel

Components

measuring spoon

The amount of the dosage form in the primary package

170 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antacid

Anatomical and therapeutic characteristics

A02AX Antacids, in combination with other drugs

Dosage form

Suspension for oral administration

Expiration date in days

730

The target audience

Children

Package weight, g

170

Mode of application

:

Treatment < br> Adults and children over 15 years old < br> 5-10 ml (1-2 scoops) or 1 sachet 3-4 times a day. < br> If necessary, a single dose can be increased to 15 ml (3 scoops). < br> Children from 10 to 15 years old < br> Applied in a dose equal to half the dose for adults - 1 scoop 2-4 times a day or 2 scoops 1-2 times a day or 1 sachet 1-2 once a day. < br> The drug is taken 45-60 minutes after meals and in the evening before bedtime. < br> After reaching the therapeutic effect, the daily dose is reduced to 5 ml (1 scoop) 3-4 times a day or 1 sachet 1-2 times a day for 15-20 days. < br> It is not recommended to take liquids during 15 minutes after taking the drug Almagel. < br> Before use, the suspension must be thoroughly homogenized,shaking the bottle or kneading and shaking the bag. < br> < br> For prophylaxis < br> 5-15 ml (1-3 measuring spoons) or 1 sachet 15 minutes before taking drugs with irritating effect. < br>

Dosage (volume) of the substance in the preparation

:

Aluminum hydroxide gel -2.18 g, in terms of Al2O3 -218 mg Magnesium hydroxide infusion - 350 mg, in terms of MgO - 75 mg.

Information on technical characteristics, delivery set, country of manufacture