Almagel NEO oral suspension, 170 ml

• Acute gastritis;

• chronic gastritis with increased and normal gastric secretory function (in the acute phase);

• acute duodenitis, duodenogastric reflux;

• peptic ulcer of the stomach and duodenum (in the acute phase);

• symptomatic gastrointestinal ulcers of various origins;

• erosion of the mucous membrane of the upper gastrointestinal tract;

• gastroesophageal reflux, reflux esophagitis;

• acute pancreatitis, exacerbation of chronic pancreatitis;

• gastralgia, heartburn (after excessive consumption of ethanol, nicotine, coffee, medication;

• an incorrect diet that negatively affects the functioning of the gastrointestinal tract);

• flatulence; fermentative or putrid dyspepsia.

Inside, 1 hour after meals and at night, adults 1 sachet or 2 dosage spoons 4 times a day.

Maintenance dose - 2 dosage spoons or 1 sachet 4 times a day for 2-3 months.

When reflux esophagitis is taken a short time after meals, the course of treatment is 2-3 months.

With occasional use (discomfort as a result of inaccuracies in the diet, etc.) - 1 sachet or 2 dosage spoons once.

Children: over 10 years old - usually 1/2 adult dose.

It is advisable to take the drug undiluted. It is not recommended to drink liquid after taking the drug earlier than 0.5 hours.

Before use, the suspension must be shaken well.

Hypersensitivity, severe renal dysfunction.

Trade name of the drug: AlmagelЃ Neo

International non-proprietary name:

Algeldrat + Magnesium hydroxide + Simethicone

Dosage form:

Oral suspension

Composition
5 ml (one scoop) of the suspension contains:

Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 340mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 395 mg;
Simethicone (simethicone emulsion - in terms of dimethicone) 36 mg;

The content of excipients in 5 ml of suspension: hydrogen peroxide solution 30% 0.495 mg, sorbitol 474.60 mg, sodium saccharinate 1.13 mg, hyetellose 5.65 mg, citric acid monohydrate 5.65 mg, ethyl parahydroxybenzoate 7.90 mg, propyl parahydroxyben -zoate 3.40 mg, propylene glycol 113.00 mg, macrogol 4000 452.00 mg, orange flavor 2.26 mg, ethanol 96% 113.00 mg, purified water to 5 ml.

10 ml (1 sachet) suspension contains:

Active substances:
Algeldrat (Aluminum hydroxide gel - in terms of aluminum hydroxide) 680 mg;
Magnesium hydroxide (Magnesium hydroxide paste - in terms of magnesium hydroxide) 790 mg;
Simethicone (simethicone emulsion - in terms of dimethicone) 72 mg;

The content of excipients in 10 ml of suspension : hydrogen peroxide solution 30% 0.990 mg, sorbitol 949.20 mg, sodium saccharinate 2.26 mg, hyetellose 11.30 mg, citric acid monohydrate 1130 mg, ethyl parahydroxybenzoate 15.80 mg, propyl parahydroxybenzoate 6, 80 mg, propylene glycol 226.00 mg, macrogol 4000 904.00 mg, orange flavor 4.52 mg, ethanol 96% 226.00 mg, purified water up to 10 ml.

Description A
white or almost white suspension with an orange scent.

Pharmacotherapeutic group
Antacid + carminative ATX code: A02AF02

Pharmacological properties
Pharmacodynamics
Combined remedy, the action of which is due to its constituent components. It has an antacid, absorbent, enveloping, carminative effect. Algeldrate (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, lower the acidity of gastric juice, and bind bile acids. The laxative effect of magnesium hydroxide balances the ability of Algeldrat to slow down intestinal motility. Simethicone hinders the formation of gas bubbles and promotes their destruction. The gases released during this are absorbed by the intestinal walls and excreted from the body due to peristalsis. Pharmacokinetics Due to physiological and chemical inertness, Simethicone is not absorbed into organs and tissues and, after passing through the gastrointestinal tract (GIT), is excreted unchanged.The absorption of aluminum and magnesium ions in the intestine is low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal failure, the level of aluminum and magnesium in the blood can rise to toxic levels as a result of impaired excretion.

Indications for use

• Acute gastritis;

• chronic gastritis with increased and normal gastric secretory function (in the acute phase);

• acute duodenitis, duodenogastric reflux;

• peptic ulcer of the stomach and duodenum (in the acute phase);

• symptomatic gastrointestinal ulcers of various origins;

• erosion of the mucous membrane of the upper gastrointestinal tract;

• gastroesophageal reflux, reflux esophagitis;

• acute pancreatitis, exacerbation of chronic pancreatitis;

• gastralgia, heartburn (after excessive consumption of ethanol, nicotine, coffee, medication;

• an incorrect diet that negatively affects the functioning of the gastrointestinal tract);

• flatulence; fermentative or putrid dyspepsia.

Contraindications

• Hypersensitivity

• chronic renal failure,

• pregnancy,

• Alzheimer's disease,

• hypophosphatemia,

• children up to age 10,

• congenital fructose intolerance.

With caution - lactation, liver disease, alcoholism, traumatic brain injury, brain disease, epilepsy, children and adolescence from 10 to 18 years.

Method of administration and dosage

Adults
Inside, 2 scoops or 1 packet of orange-flavored suspension 4 times a day 1 hour after a meal and in the evening before bedtime. If necessary, a single dose can be increased to 4 scoops or 1 sachet 4 times a day, but the maximum daily dose should not exceed 12 scoops (b bags).

Children over 10 years of age The
dosage is determined by the attending physician - usually 1/2 the dose for adults. The course of treatment is no more than 4 weeks. Before taking, the suspension must be mixed by shaking the bottle or carefully kneading the sachet. It is advisable to take AlmagelЃ Neo without diluting with water or drinking it. It is not recommended to take liquid within half an hour after taking the drug.

Side effect
Allergic reactions, nausea, vomiting, change in taste, constipation, diarrhea. With long-term use in high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesemia, hyperaluminaemia, encephalopathy, nephrocalcinosis, renal dysfunction. In patients with concomitant renal failure - thirst, lowering blood pressure, hyporeflexia.

Overdose
Symptoms. Prolonged use of high doses can lead to the development of hypermagnesemia, which is characterized by rapid fatigue, facial flushing, exhaustion, muscle weakness and inadequate behavior.
Signs of metabolic alkalosis may also be observed: mood changes, mental impairment, muscle numbness or pain, nervousness and fatigue, slow breathing, unpleasant taste sensations. Urgent action. It is necessary to immediately take measures for the rapid elimination of the drug - gastric lavage, stimulation of vomiting, intake of activated carbon.

Interaction with other medicinal products
AlmagelЃ Neo reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, H2-histamine receptor blockers, beta-blockers, diflunisal, ketoconazole and itraconazole, antibiotics, isoniazidine pivampicillin, rifampicin, indirect anticoagulants, barbiturates, fexofenadine, dipyridamole, zalcitabine, chenodeoxycholic and ursodeoxycholic acids, penicillamine and lansoprazole. M-anticholinergics, slowing down gastric emptying, enhance and lengthen the effect of the drug.

special instructions
The interval between taking AlmagelЃ Neo and other medicines should be 1-2 hours. With long-term use, you should ensure a sufficient intake of phosphorus from food. Due to the lack of data from controlled clinical trials, women who are breastfeeding should take AlmagelЃ Neo only after consulting a doctor. One scoop (5 ml) of the preparation contains 0.113 g of ethyl alcohol. One sachet (10 ml) of the drug contains 0.226 g of ethyl alcohol. As a result of this, complications may arise in patients with liver and brain diseases, in those suffering from alcoholism and epilepsy, in pregnant women and in children under 18 years of age. The daily dose of the drug (8 scoops or 4 sachets) contains 0.904 g of ethyl alcohol, the maximum daily dose of the suspension (12 scoops or 6 sachets) contains 1.356 g of ethyl alcohol.One scoop (5 ml) of AlmagelЃ Neo contains 0.475 g of sorbitol. One sachet (10 ml) of the suspension contains 0.950 g of sorbitol. Sorbitol is contraindicated in congenital fructose intolerance and may cause stomach irritation and diarrhea. AlmagelЃ Neo does not adversely affect the ability to drive vehicles and work with mechanisms that require increased concentration of attention and speed of psychomotor reactions.requiring increased concentration of attention and speed of psychomotor reactions.requiring increased concentration of attention and speed of psychomotor reactions.

Release form
Suspension for oral administration.
170 ml or 200 ml of the drug in a glass bottle. Each bottle together with instructions for use and a 5 ml measuring spoon in a cardboard box.
170 ml or 200 ml of the drug in a bottle made of polyethylene terephthalate. Each bottle together with instructions for use and a 5 ml measuring spoon in a cardboard box.
10 ml of the drug in a bag made of multilayer foil. 10 or 20 sachets together with instructions for use in a cardboard box,

Storage conditions
In a dark place at a temperature not exceeding 25 ? C. Do not freeze! Keep out of the reach of children!

Shelf life is
2 years.
Do not use after the expiration date printed on the package.

Terms of dispensing from pharmacies
Without prescription.