Allergen p lts berez | Staloral Allergen pollen of birch supporting course, bottle of 10 ml, 2 pcs.

Special Price $119.60 Regular Price $139.00
In stock
SKU
BID511821
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Latin name

STALORAL BIRCH POLLEN ALLERGEN
Latin name

STALORAL BIRCH POLLEN ALLERGEN

Release form

drops sublingual

Packaging

10 ml vials.

Pharmacological action

Toff plus has a sedative effect,, leading to a positive change in the production of cytokines (a decrease in IL-4 and an increase in -interferon) that regulate the production of IgE.

Conducting ASIT also inhibits the development of both the early and late phases of an immediate allergic reaction.

Indications

Allergen specific immunotherapy (ASIT) for patients with type 1 allergic reaction (IgE mediated), rhinitis, conjunctivitis, mild or moderate seasonal bronchial asthma, with increased sensitivity to birch pollen.

Immunotherapy can be carried out for adults and children from 5 years of age.

Contraindications

Hypersensitivity to one of the excipients (see the list of excipients)

Autoimmune diseases, immunocomplex diseases, immunodeficiencies

Malignant neoplasms

Uncontrolled or severe bronchial asthma (forced expiratory flow is less than 70%)

Therapy with beta-blockers (including topical ophthalmology)

Severe inflammatory diseases of the red mucosal ulcer, for example,

Use during pregnancy and lactation

Pregnancy

Do not start ASIT during pregnancy.

If pregnancy occurs at the first stage of treatment, then therapy should be discontinued. If pregnancy arose during the period of maintenance therapy, the doctor should evaluate the possible benefits of ASIT based on the general condition of the patient.

No adverse effects reported with ASIT in pregnant women.

Breastfeeding

It is not recommended to start the course of ASIT during breastfeeding.

If a woman continues to undergo ASIT during lactation, no unwanted symptoms or reactions are expected in children.

There is no clinical data on the use of the drug during lactation.

Composition

Active ingredient: Allergen extract from birch pollen 10 TS / ml *, 300 TS / ml

Excipients: sodium chloride, glycerol, mannitol, purified water

* TS / ml - Reactivity Index - a biological unit of standardization.

Dosage and Administration

ASIT is more effective when treatment is started early in the course of the disease.

Dosage and regimen

The dosage and regimen of the drug are the same for all ages, but can be changed depending on the individual reactivity of the patient.

The attending physician adjusts the dosage and treatment regimen in accordance with the possible symptomatic changes in the patient and the individual reaction to the drug.

It is advisable to start treatment no later than 2-3 months before the expected flowering season and continue throughout the flowering period.

Treatment consists of two stages: initial and maintenance therapy.

1. Initial therapy is started with daily administration of a drug with a concentration of 10 TS / ml (blue bottle cap) with a single tap on the dispenser and gradually increases the daily dosage to 10 clicks. One click on the dispenser is about 0.1 ml of the drug.

Next, go to the daily intake of the drug at a concentration of 300 TS / ml (purple bottle cap), starting from one click and gradually increasing the number of clicks to the optimum (well tolerated by the patient). The first stage can last 9-21 days. During this period, the maximum dosage is achieved, individual for each patient (from 4 to 8 taps daily of a preparation of a concentration of 300 TS / ml), after which they proceed to the second stage.

Recommended initial course of ASIT:

Bottle of 10 TS / ml (blue cap)

Bottle of 300 TS / ml (purple cap)

Day

Number of clicks on the dispenser

Day

Number of clicks on the dispenser

1

1 srdlpp 1 1 srdlpp 1 1 srdlpp 1 1 srdlpp 1 1 srdlpp 1 2

2

8

2

3

4

9

4

4

6

10

6

5

8

11

8

6 Supportive therapy with a constant dose using a bottle of a concentration of 300 TS / ml.

The optimal dose achieved at the first stage of initial therapy is continued to be taken at the second stage of maintenance therapy.

Recommended dosing schedule: 4 to 8 taps on the dispenser daily or 8 taps 3 times a week.

Duration of treatment

Allergen specific immunotherapy is recommended for the above two-stage courses (2-3 months before the expected flowering season before the end of the season) for 3-5 years.

If after treatment no improvement has occurred during the first flowering season, the feasibility of ASIT should be reviewed.

How to use

Before taking the drug, make sure that:

has not expired.

is using a vial of the correct concentration.

The drug is recommended to be taken in the morning before breakfast.

The drug should be dripped directly under the tongue and held for 2 minutes, then swallow.

Children are advised to use the drug with the help of adults.

To ensure the safety and preservation of the drug, the bottles are hermetically sealed with plastic caps and sealed with aluminum caps.

Interruption in

medication If you skip taking the medication for a long time, you should consult your doctor.

If the pass in taking the drug was less than one week, it is recommended to continue treatment without changes.

If the pass in taking the drug was more than one week at the initial stage or with maintenance therapy, it is recommended to carry out the treatment again with one click on the dispenser, using the same concentration of the drug (as before the break), and then increase the number of clicks, according to the scheme of the initial stage of therapy, to the optimal well-tolerated dose.

Side effects

Conducting ASIT can cause adverse reactions, both local and general.

Dosage and treatment regimen may be reviewed by the attending physician in case of an individual reaction or changes in the general condition of the patient.

Local reactions: oral: itching in the mouth, swelling, discomfort in the mouth and throat, violation of the salivary glands (increased salivation or dry mouth)

gastroenterological reactions: abdominal pain, nausea, diarrhea.

Usually these symptoms quickly disappear, and there is no need to change the dosage and treatment regimen. In case of frequent occurrence of symptoms, the possibility of continuing therapy should be reviewed.

General reactions are rare: rhinitis, conjunctivitis, asthma, urticaria require symptomatic treatment with H1 antagonists, beta-2 mimetics, or corticosteroids (oral). The doctor should review the dosage and treatment regimen or the possibility of continuing ASIT.

in extremely rare cases, generalized urticaria, angioedema, laryngeal edema, severe asthma, anaphylactic shock are possible, which requires the cancellation of ASIT.

Rare side effects, not related to Ig-E mediator reactions:

asthenia, headache

exacerbation of preclinical atopic eczema

delayed reactions of the type of serum sickness with arthralgia, myalgia, urticaria, nausea, adenopathy, fever, which requires the abolition of ASIT.

All side effects should be reported to your healthcare provider.

Overdose

In the event of exceeding the prescribed dose, the risk of side effects increases, requiring symptomatic treatment.

Storage conditions

Store and transport at a temperature of 2 to 8 РC.

Keep out of the reach of children.

Deystvuyushtee substance

Allergen p lyts berez

dosage form

drops for oral dosage form

Possible product names

Staloral Allergen birch supporting course, bottle 10 ml, 2 pcs.

Stallerzhen, France

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