Albendazole 2.5% 1L
DESCRIPTION
Albendazole suspension (Albendasolum suspension) - suspension for oral administration for deworming animals. In appearance, the drug is a homogeneous suspension of white or light gray color. During storage, delamination is allowed, which disappears after shaking.
COMPOSITION
In 100 g as an active ingredient, albendazole is 2.5 g or 10 g, respectively, as well as auxiliary substances: ethyl alcohol - 0.875 g and 3.5 g, respectively, water-soluble methylcellulose -1.75 g, citric acid - to pH 4- 5, distilled water - up to 100 g.
PHARMACOLOGICAL PROPERTIES
Albendazole suspension refers to broad-spectrum anthelmintic drugs.
Albendazole - methyl {5- (propylthio) -1-H-benziamidazol-2-yl} carbamate, which is part of the drug, has a wide spectrum of anthelmintic action, is effective in mono- and polyinvasions, is active against imago and larvae of nematodes, trematodes, as well as the imago of cestodes; having an ovocidal effect, it reduces the infection of pastures with helminth eggs.
Albendazole selectively inhibits the polymerization of beta-tubulin, disrupts the activity of the microtubular system of cells of the intestinal canal of helminths; suppresses the utilization of glucose, blocks the movement of secretory granules and other organelles in the muscle cells of roundworms, causing their death.
When administered orally, albendazole is absorbed in the gastrointestinal tract and penetrates into organs and tissues; excreted from the body mainly in the form of metabolites in the urine and in small quantities in feces.
Albendazole suspension according to the degree of impact on the body according to GOST 12.1.007 refers to low-hazard substances (hazard class 4). In recommended doses, the drug is well tolerated by animals, does not have hepatotoxic and sensitizing effects.
INDICATIONS
Albendazole suspension 10% - only for cattle with a therapeutic and prophylactic purpose for nematodes, trematodes and cestodoses, incl. bunostomiasis, cooperiosis, hemonchosis, nematodyrosis, esophagosgomosis, ostertagiasis, strongyloidiasis, trichostrongylosis, habertiosis, dictyocaulosis, protostrongylosis, mulleriosis, moniesiasis and fascioliasis.
DOSES AND METHOD OF APPLICATION
DOSES AND METHOD OF APPLICATION
The drug is administered to animals once, orally, using a syringe dispenser.
With nematodes and cestodes:
Animal weight, kg Dose, ml
Cattle
up to 50kg 15ml
51-100kg 30ml
101-150kg 45ml
151-200kg 60ml
201-250 75ml
251-300 90ml
301-350kg 105ml
more than 350kg 15 ml for every 50 kg
Sheep and goats
up to 10kg 2ml
11-20kg 4ml
21-30kg 6ml
31-40kg 8ml
41-50 10ml
51-60 12ml
61-70kg 14ml
more than 70kg 2 ml for every 10 kg
With dicroceliosis and chronic fascioliasis:
Animal weight, kg Dose, ml
Cattle
up to 50kg 20ml
51-100kg 40ml
101-150kg 60ml
151-200kg 80ml
201-250 100ml
251-300 120ml
301-350kg 140ml
more than 350kg 20 ml for every 50 kg
Sheep and goats
up to 10kg 3ml
11-20kg 6ml
21-30kg 9ml
31-40kg 12ml
41-50 15ml
51-60 18ml
61-70kg 21ml
more than 70kg 3 ml for every 10 kg
A special diet and the use of laxatives before deworming are not required. Shake the container with albendazole suspension thoroughly before use. Before mass treatments, each batch of albendazole suspension is preliminarily tested on a small group of animals, for this 5-7 animals of different fatness are selected and the drug is used in the recommended doses. If no signs of toxicosis are noted in animals within two days, the drug is used for the whole livestock.
SIDE EFFECTS
With proper use and dosage, side effects are usually not observed. Intoxication due to overdose is practically impossible, since the safety limit exceeds 5 times the therapeutic dose. The maximum tolerated dose for oral administration is 7.5 ml for every 10 kg of animal weight. If a higher dose is mistakenly administered, the animal may experience anorexia, sleeping sickness, weight loss, lethargy, and impaired gastrointestinal motility. In this case, you should stop the drug administration and apply symptomatic treatment.
CONTRAINDICATIONS
A contraindication to the use of the drug is the increased individual sensitivity of the animal to albendazole.
It is forbidden to use Albendazole for acute fascioliasis, during the breeding period, pregnant cows in the first third, and pregnant sheep and goats in the first half of pregnancy, as well as malnourished and sick animals with infectious diseases.
SPECIAL INSTRUCTIONS
Slaughter of animals for meat is allowed no earlier than 14 days after the use of the drug. The meat of animals that were forcedly killed before the expiration of the specified period can be used for feeding fur animals or for the production of meat and bone meal. Milk obtained from animals treated with the drug must not be used for food purposes within 4 days after the use of albendazole. Such milk can be used to feed animals.
SHELF LIFE AND STORAGE CONDITIONS
Store the medicinal product in the manufacturer's closed packaging in a dry, dark place, separate from food and feed, at a temperature of 2 В° C to 15 В° C.
The shelf life of the medicinal product, subject to storage conditions, is 2 years from the date of production.
PACKAGING
Albendazole suspension is released packaged in 1000 ml bottles in polymer bottles closed with screw-on plastic caps with first opening control.
Specifications
KolVUP
ten
Manufacturer
Livisto
Temperature regime
from +5 to +25
Teaser
prescribed for nematodosis, cestodosis and trematodosis, including bunostomosis, cooperiosis, hemonchosis, nematodyrosis, esophagostomosis, ostertagiasis, strongyloidosis, trichostrongylosis, habertiosis, dictyronocillosis, protostrostosis