Description

pharmachologic effect

Akriderm GK is a combined preparation that has anti-inflammatory, anti-allergic, antibacterial and antifungal (fungicidal) effects. Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group, it has a bactericidal effect. Highly sensitive gram-negative microorganisms - Proteus spp. (indole positive and indole negative), Escherichia coli, Klebsiella spp., Salmonella spp., Shigella spp., Campylobacter spp., Staphylococcus spp. (methicillin-resistant). Sensitive: Enterococcus faecalis, Serratia spp., Pseudomonas spp., Acinetobacter spp., Citrobacter spp. Resistant: Neisseria meningitidis, Treponema pallidum, anaerobic microbes: Streptococcus spp. (except Streptococcus pneumoniae), Enterococcus faecalis Providencia rettgeri. Betamethasone - glucocorticosteroid,has a local anti-inflammatory, anti-edema, anti-allergic effect.

Clotrimazole is an antifungal agent from the group of imidazole derivatives for topical use.

It acts by disrupting the synthesis of ergosterol, which is an integral part of the cell membrane of fungi.

Possesses a wide spectrum of action.

It is active against pathogenic dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis), yeast and mold fungi (Candida spp., Torulopsis glabrata, Rhodotorula spp., Pityrosporum orbiculare).

Indications

Simple and allergic dermatitis (especially complicated by secondary infection), diffuse neurodermatitis (including atopic dermatitis), limited neurodermatitis (including simple chronic lichen), eczema, dermatomycosis (dermatophytosis, candidiasis, versicolor versicolor), especially when localization in the groin and large folds of the skin.

Contraindications

Hypersensitivity to any of the components of the drug, tuberculosis of the skin, skin manifestations of syphilis, chickenpox, herpes simplex, post-vaccination skin reactions, open wounds, children (up to 2 years).

Application during pregnancy and lactation

During pregnancy (especially in the first trimester), topical application of the ointment in pregnant women is allowed only in cases where the intended benefit to the mother outweighs the potential risk to the fetus.

In such cases, the use of the drug should be short-lived and limited to small areas of the skin.

It is not known whether the components of the drug are excreted in breast milk.

Therefore, when prescribing Akriderm GK ointment during lactation, it is recommended to stop breastfeeding.

special instructions

Avoid contact with eyes.

When a stable bacterial or fungal microflora appears, the drug should be canceled and appropriate therapy should be prescribed.

Due to the fact that in children the area of the skin in relation to body weight is larger than in adults, as well as the epidermis is insufficiently developed, with external use of the drug, absorption of a proportionally larger amount of active substances is possible and, therefore, there is a greater risk of developing systemic side effects ...

The drug should be used in children as soon as possible and in compliance with all precautions.

Structure

100 g of ointment contain:

Active substances: betamethasone dipropionate in terms of 100% substance - 0.064 g, clotrimazole in terms of 100% substance - 1 g, gentamicin sulfate in terms of gentamicin - 0.1 g

Excipients: propyl parahydroxybenzoate (nipazole), liquid paraffin (liquid paraffin), isopropyl myristate, petroleum jelly.

Method of administration and dosage

Outwardly.

Ointment Akrider GK is applied to the affected areas of the skin, rubbing in a small amount, 2 times a day.

The duration of treatment is determined individually and depends on the nosological form and severity of the disease.

With dermatomycosis of the feet, the average duration of treatment is 2-4 weeks.

If clinical improvement does not occur in the near future, it is necessary to clarify the diagnosis or change the treatment regimen.

Side effects

Itching, burning, irritation, dry skin, folliculitis, hypertrichosis, steroid acne, hypo-pigmentation, allergic reactions.

When using occlusive dressings - maceration, infection, skin atrophy, striae, prickly heat.

With prolonged treatment or application to a large surface - the development of systemic side effects: increased body weight, osteoporosis, increased blood pressure, edema, ulceration of the mucous membrane of the gastrointestinal tract, exacerbation of hidden foci of infection, hyperglycemia, agitation, insomnia, dysmenorrhea.

Drug interactions

The interaction of Akriderma GK with other drugs has not been established.

Overdose

Symptoms: phenomena of hypercortisolism.

Treatment: gradual withdrawal of the drug.

Symptomatic therapy.

If necessary, correction of electrolyte disturbances.

Storage conditions

At temperatures from 15 to 25 ° C.

Keep out of the reach of children.

Active substance

Betamethasone, Gentamicin, Clotrimazole

Name ENG

AKRIDERM GK

Clinical and pharmacological group

GCS for local use + antibiotic aminoglycoside + antifungal agent

ATX code

Betamethasone in combination with other drugs

Dosage

0.05% + 0.1% + 1% x 30g

Structure

100 g of ointment contain: Active substances: betamethasone dipropionate in terms of 100% substance - 0.064 g, clotrimazole in terms of 100% substance - 1 g, gentamicin sulfate in terms of gentamicin - 0.1 g

Excipients: propyl parahydroxybenzoate (nipazole), liquid paraffin (liquid paraffin), isopropyl myristate, petroleum jelly.

Indications

Simple and allergic dermatitis (especially complicated by secondary infection), diffuse neurodermatitis (including atopic dermatitis), limited neurodermatitis (including simple chronic lichen), eczema, dermatomycosis (dermatophytosis, candidiasis, versicolor versicolor), especially when localization in the groin and large folds of the skin.

Contraindications

Hypersensitivity to any of the components of the drug, tuberculosis of the skin, skin manifestations of syphilis, chickenpox, herpes simplex, post-vaccination skin reactions, open wounds, children (up to 2 years).

INN / Active ingredient

betamethasone

Storage conditions and periods

At a temperature of 15-25 degrees.

Expiration date: 2 years

Specifications