Ainil 10% 100ml

DESCRIPTION

Ainil 10% is a non-steroidal anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic effects. It is a colorless transparent solution for injection.

COMPOSITION

The drug in 1 ml contains 100 mg of ketoprofen as an active ingredient, as well as 10 mg of benzyl alcohol and a filler up to 1 ml.

PHARMACOLOGICAL PROPERTIES

Ainil is a non-steroidal anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic effects. Ketoprofen, which is part of Ainil, is a derivative of propionic acid from the carboxylic acid group. The mechanism of action of ketoprofen is to inhibit the enzyme cyclooxygenase and suppress the synthesis of prostaglandins and thromboxane. Ketoprofen in therapeutic doses inhibits mainly cyclooxygenase-II, providing anti-inflammatory and antipyretic effects, and does not affect cyclooxygenase-I, minimizing the development of side effects such as bleeding, ulceration and impaired renal function. The analgesic effect of ketoprofen is associated with the inhibition of bradykinin directly, which excites painful nerve endings and thereby provokes pain. In addition to its anti-bradykinin activity, ketoprofen has an effect on the central nervous system, suppressing pain perception. In horses, ketoprofen counteracts the effects of endotoxin and prevents the intestinal spasm caused by bradykinin. After intramuscular administration of Ainil to cattle, ketoprofen is well absorbed, reaching a maximum concentration in the blood plasma 1 hour after injection. More than 98% of ketoprofen binds to blood plasma proteins and is concentrated in inflamed tissues. The drug is excreted from the body mainly in the urine. In the recommended doses, Ainil has no local irritating, sensitizing, mutagenic, carcinogenic, embryotoxic and teratogenic effects. In horses, ketoprofen counteracts the effects of endotoxin and prevents the intestinal spasm caused by bradykinin. After intramuscular administration of Ainil to cattle, ketoprofen is well absorbed, reaching a maximum concentration in the blood plasma 1 hour after injection. More than 98% of ketoprofen binds to blood plasma proteins and is concentrated in inflamed tissues. The drug is excreted from the body mainly in the urine. In the recommended doses, Ainil has no local irritating, sensitizing, mutagenic, carcinogenic, embryotoxic and teratogenic effects. In horses, ketoprofen counteracts the effects of endotoxin and prevents the intestinal spasm caused by bradykinin. After intramuscular administration of Ainil to cattle, ketoprofen is well absorbed, reaching a maximum concentration in the blood plasma 1 hour after injection. More than 98% of ketoprofen binds to blood plasma proteins and is concentrated in inflamed tissues. The drug is excreted from the body mainly in the urine. In the recommended doses, Ainil has no local irritating, sensitizing, mutagenic, carcinogenic, embryotoxic and teratogenic effects. reaching the maximum concentration in blood plasma 1 hour after injection. More than 98% of ketoprofen binds to blood plasma proteins and is concentrated in inflamed tissues. The drug is excreted from the body mainly in the urine. In the recommended doses, Ainil has no local irritating, sensitizing, mutagenic, carcinogenic, embryotoxic and teratogenic effects. reaching the maximum concentration in blood plasma 1 hour after injection. More than 98% of ketoprofen binds to blood plasma proteins and is concentrated in inflamed tissues. The drug is excreted from the body mainly in the urine. In the recommended doses, Ainil has no local irritating, sensitizing, mutagenic, carcinogenic, embryotoxic and teratogenic effects.

INDICATIONS

Prescribed to cattle, sports horses and pigs for the treatment of inflammatory processes in acute and chronic diseases of the musculoskeletal system (arthrosis, arthritis, dislocations, edema, tendovaginitis, trauma), pain syndrome of various etiologies (traumatic and postoperative pain, colic, herniated intervertebral discs), and also as an antipyretic agent for diseases accompanied by fever and depression. In combination with antibacterial drugs for the complex treatment of infections of the respiratory tract, purulent-necrotic lesions of the lower extremities and clinical forms of mastitis.

APPLICATION

Ainil 10% is administered to cattle intramuscularly or intravenously at the rate of 3 ml of the drug per 100 kg of animal weight, which corresponds to 3 mg of ketoprofen per 1 kg of animal weight, once a day for 1 to 3 days. For sports horses - intravenously at the rate of 1 ml of the drug per 45 kg of animal weight, which corresponds to 2.2 mg of ketoprofen per 1 kg of animal weight, for the treatment of disorders of the musculoskeletal system 1 time per day for 3 - 5 days, and once for symptomatic treatment of colic. Additional administration of Ainil 10% to horses with colic symptoms should be performed after a preliminary re-clinical analysis of the animal. Pigs - intramuscularly at the rate of 3 ml of the drug per 100 kg of animal weight, which corresponds to 3 mg of ketoprofen per 1 kg of animal weight, once a day for 1 - 3 days.

CONTRAINDICATIONS

Increased individual sensitivity to drug components. Stomach ulcer and 12 duodenal ulcer, hemorrhagic syndrome, as well as severe renal and hepatic failure. Ainil should not be administered concurrently with other non-steroidal anti-inflammatory drugs, glucocorticoids, diuretics and anticoagulants. Do not mix with other medicines in the same syringe. It is not recommended to use horses with meat production.

SIDE EFFECTS

Allergic reactions may occur in animals that are hypersensitive to the drug. In some animals, after intramuscular injection of Ainil at the injection site, edema, pain with pressure or swelling may appear, which spontaneously disappear within a week after the end of treatment with the drug. In case of overdose, loss of appetite, vomiting, or diarrhea may occur. In this case, it is necessary to stop the drug administration.

Slaughter of cattle for meat is allowed after 5 days, and pigs - 4 days after the last use of the drug. The meat of animals that were forcedly killed before the expiration of the specified period can be used for feeding fur animals or for the production of meat and bone meal. Milk from cattle can be used for food purposes without restrictions.

STORAGE

Store in a dry, dark place, out of reach of children and animals, at temperatures from 5 В° C to 25 В° C. Shelf life is 2 years. After opening the bottle, the drug can be used within 7 days.

PACKING

Packaged in dark glass bottles of 100 ml, which are put in cardboard boxes.

Specifications

KolVUP

50

Manufacturer

Livisto

Temperature regime

from +5 to +25

Teaser

anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic effects