Afrin Extra nasal spray for rhinitis with eucalyptus and menthol , 15 ml., Bayer

Release form, composition and packaging

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Nasal spray 0.05% in the form of a gel-like suspension of white or almost white color, with a characteristic odor.

1 ml

oxymetazoline hydrochloride 500 mcg

microcrystalline cellulose and sodium carmellose (avicel RC-591) - 30 mg, sodium hydrogen phosphate - 975 μg, sodium dihydrogen phosphate monohydrate - 5.525 mg, disodium edetate dihydrate - 300 μg, macrogol 1450 - 50 mg, povidone K29-32 - 30 mg, benzyl alcohol - 3 mg, cineole - 200 μg, camphor - 200 μg, levomenthol - 600 μg, benzalkonium chloride solution 17% - 1.471 mg, polypropylene glycol - 5 mg, purified water - qs up to 1 ml.

15 ml - plastic bottles with a dosing device (1) - cardboard packs.

pharmachologic effect

Adrenomimetic agent for topical use.

Has a vasoconstrictor effect.

With intranasal administration, the swelling of the mucous membrane of the upper respiratory tract decreases.

When instilled into the conjunctival sac, it reduces the swelling of the conjunctiva.

Pharmacokinetics

The effect is manifested 15 minutes after application and lasts for 6-8 hours.

Indications for use

Difficulty in nasal breathing with colds, sinus inflammation, eustachitis, hay fever, allergic rhinitis, congestion and edema of the conjunctiva.

Contraindications for use

Inflammation of the nasal mucosa without secretion, chronic heart failure, hyperthyroidism, diabetes mellitus, pregnancy, children under 6 years of age (for eye drops), hypersensitivity to oxymetazoline, atrophic rhinitis, lactation period, arrhythmias, severe atherosclerosis, arterial hypertension, chronic renal failure , angle-closure glaucoma.

Dosage regimen

Apply topically.

Side effect

From the respiratory system: transient dryness and burning of the nasal mucosa, dry mouth and throat, sneezing are possible

with prolonged use, the appearance of reactive hyperemia of the mucous membrane, atrophy of the mucous membrane is possible.

On the part of the cardiovascular system: palpitations

rarely - arterial hypertension.

From the side of the central nervous system: increased excitability, dizziness, headache, sleep disturbances

with prolonged use - tachyphylaxis.

From the digestive system: nausea.

From the side of the organ of vision: with conjunctival administration, mydriasis, paresis of accommodation, irritation of the conjunctiva and surrounding tissues, eyelid retraction are possible.

Drug interactions

With the simultaneous appointment of MAO inhibitors and tricyclic antidepressants, an increase in blood pressure is possible.

Oxymetazoline slows down the absorption of local anesthetic drugs, lengthens their effect.

The co-administration of other vasoconstrictor drugs increases the risk of side effects.

Application during pregnancy and lactation

Oxymetazoline is contraindicated during pregnancy and lactation (breastfeeding).

Special instructions In the recommended dosage without consulting a doctor, you can use no more than 3 days.

Avoid getting the drug intended for intranasal administration in the eyes.

Influence on the ability to drive vehicles and control mechanisms The drug affects vision, a decrease in the reaction rate is possible.

Name ENG

AFRIN EXTRO

Clinical and pharmacological group

A vasoconstrictor drug for local use in ENT practice

ATX code

Oxymetazoline

Dosage

0.05% x 15ml

Structure

Active ingredient: oxymetazoline hydrochloride 0.5 mg

Excipients: disodium edetate dihydrate - 300 μg, sodium hydrogen phosphate - 975 μg, sodium dihydrogen phosphate monohydrate - 5.525 mg, povidone K29-32 - 30 mg, benzalkonium chloride solution 17% - 1.471 mg, macrogol 1450 - 50 mg, benzyl alcohol - 2.5 mg, microcrystalline cellulose and sodium carmellose (Avicel RC-591) - 30 mg, lemon flavoring - 1.5 mg, purified water - qs up to 1 ml.

INN / Active ingredient

Oxymetazoline

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 2 years

Specifications

Category

Runny nose

Scope of the medicinal product

Ear, Throat, Nose

Release form

Spray

Manufacturer country

Canada

Package quantity, pcs

one

Scope of application

Virology

Minimum age from

6 years

Way of introduction

Through the respiratory tract

Vacation conditions

Without recipe

Volume, ml.

15 ml

Brand name

Afrin

The amount of the dosage form in the primary package

15 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Decongestant - alpha adrenergic agonist

Anatomical and therapeutic characteristics

R01AA05 Oxymetazoline

Dosage form

Nasal spray

Expiration date in days

730

The target audience

Children

Package weight, g

twenty

Mode of application

:

Shake the bottle vigorously before each use.

Before using the nasal spray for the first time, it must be calibrated" by pressing the spray head several times.

Adults and children over 6 years old - 2-3 injections into each nasal passage with an interval of 10-12 hours. In adults, the frequency of application can be increased up to 3 times a day in adults.

It is not recommended to exceed the indicated dose.

Information on technical characteristics, delivery set, country of manufacture "