acyclovir | Acyclovir Belupo tablets are covered. captivity. about. 400 mg 35 pcs.
Special Price
$20.37
Regular Price
$28.00
In stock
SKU
BID467557
Release form
Tablets.
Tablets.
Release form
Tablets.
35rd
packaging
headlightmacrological effect of
Acyclovir is an antiviral drug, a synthetic analogue of the acyclic purine nucleoside, which has a highly selective effect on herpes viruses. Inside the virus-infected cells, a series of sequential reactions of the transformation of acyclovir into acyclovir mono-, di- and triphosphate undergoes a viral thymidine kinase. Acyclovir triphosphate is integrated into the chain of viral DNA and blocks its synthesis through competitive inhibition of viral DNA polymerase.
In vitro, acyclovir is effective against herpes simplex virus - Herpes simplex type I and II, against Varicella zoster virus higher concentrations are required to inhibit Epstein-Barr virus.
In vivo acyclovir is therapeutically and prophylactically effective primarily for viral infections caused by Herpes simplex.
Indications
Treatment of infections of the skin and mucous membranes, caused by Herpes simplex virus types 1 and 2, both primary and secondary, including genital herpes
prevention of exacerbations of recurrent infections caused by Herpes simplex virus types 1 and 2 in patients with normal immune status
prevention of primary and recurrent infections caused by Herpes simplex virus Types 1 and 2, in patients with
immunodeficiency as part of complex therapy in patients with severe immunodeficiency: with HIV infection (AIDS stage, early clinical manifestations and an expanded clinical picture) and in patients transplantation of bone marrow transplantation
treatment of primary and recurrent infections caused by the Varicella zoster virus (chickenpox, shingles).
Contraindications
- Hypersensitivity to acyclovir, ganciclovir, famciclovir, Valaciclovir or any auxiliary substance of the drug Acyclovir Belupo
- lactation period
- children's age up to 3 years (for this dosage form).
Precautions: dehydration, renal failure, neurological disorders, including in the anamnesis.
Use during pregnancy and lactation
Use during pregnancy is only possible if the intended benefit to the mother outweighs the potential risk to the fetus.
If you need to use the drug during lactation, you should stop breastfeeding.
Special instructions
Prolonged or repeated treatment with acyclovir of patients with reduced immunity can lead to the appearance of strains of viruses that are insensitive to its action. Apply strictly as prescribed by the doctor to avoid complications in adults and children over 3 years old.
Use with caution in patients with impaired renal function, elderly patients due to an increase in the half-life of acyclovir.
When using the drug Acyclovir Belupo, it is necessary to ensure the flow of a sufficient amount of fluid.
When taking the drug, kidney function (blood urea and blood plasma creatinine) should be monitored.
Acyclovir does not prevent sexual transmission of herpes, therefore during treatment it is necessary to refrain from sexual intercourse, even in the absence of clinical manifestations.
Composition of
1 tab: - acyclovir 400 mg
Excipients:
povidone,
carboxymethyl starch sodium,
microcrystalline cellulose,
silicon dioxide colloidal, srdlpp magnesium.
Shell composition:
Opadry Pink OY-24926 (hypromellose, titanium dioxide, macrogol, red iron oxide, yellow iron oxide).
Dosage and Administration
Inside.
Treatment should be started as soon as possible, immediately after the onset of the first symptoms of the disease.
The dosage regimen is set individually, depending on the severity of the disease.
In the treatment of infections of the skin and mucous membranes caused by Herpes simplex type I and II, for adults and children over 3 years of age, the drug Acyclovir Belupo is prescribed 200 mg 5 times / day. for 5 days at 4-hour intervals throughout the day and with an 8-hour interval at night. In more severe cases of the disease, the course of treatment can be extended as prescribed by the doctor.
As part of complex therapy for severe immunodeficiency, including the expanded clinical picture of HIV infection (including the early clinical manifestations of HIV infection and the stage of AIDS), 400 mg 5 times / day are prescribed after bone marrow implantation.
For the prevention of relapse of infections caused by Herpes simplex viruses type I and II, patients with normal immune status and with relapse are prescribed 200 mg 4 times / day. every 6 hours
For the prevention of infections caused by Herpes simplex viruses type I and II, adults and children older than 3 years with immunodeficiency, the drug Acyclovir Belupo is recommended to appoint 200 mg 4 times / day. every 6 hours, the maximum dose is up to 400 mg of acyclovir 5 times / day. depending on the severity of the infection.
In the treatment of infections caused by Varicella zoster, adults are prescribed 800 mg 5 times / day. every 4 hours during the day and with an 8-hour interval at night. The duration of treatment is 7-10 days. Children over 3 years of age are prescribed 20 mg / kg 4 times / day. within 5 days, for children weighing more than 40 kg, the drug is prescribed in the same dosage as adults.
In the treatment of infections caused by Herpes zoster, adults are prescribed 800 mg 4 times a day every 6 hours for 5 days.
In patients with impaired renal function: In the treatment and prevention of infections caused by Herpes simplex, in patients with CC less than 10 ml / min, the dose should be reduced to 200 mg 2 times / day. at 12 hour intervals.
In the treatment of infections caused by Varicella zoster in patients with CC less than 10 ml / min, it is recommended to reduce the dose to 800 mg 2 times / day. with 12-hour intervals with CC up to 25 ml / min, 800 mg are prescribed 3 times / day. at 8 hour intervals.
The drug Acyclovir Belupo is taken during or immediately after a meal and washed down with a sufficient amount of water.
Side effects
The drug Acyclovir Belupo is usually well tolerated.
From the digestive system: in isolated cases - abdominal pain, nausea, vomiting, diarrhea.
On the part of laboratory indicators: a slight increase in the activity of liver enzymes, rarely - a slight increase in the levels of urea and creatinine, hyperbilirubinemia, leukopenia, erythropenia.
From the side of the central nervous system and peripheral nervous system: rarely - headache, weakness in some cases - tremors, dizziness, increased fatigue, drowsiness, confusion, hallucinations, paresthesia, agitation.
Allergic reactions: anaphylactic reactions, skin allergic reactions (pruritus, Lyell's syndrome, urticaria, erythema multiforme exudative, incl. Stevens-Johnson syndrome), peripheral edema.
Other: rarely - alopecia, fever, myalgia, visual impairment, lymphadenopathy.
Drug Interactions
Concomitant use with probenecid leads to an increase in the average half-life and a decrease in clearance of acyclovir.
Concomitant use with nephrotoxic drugs increases the risk of impaired renal function.
Strengthening of the effect is noted with the simultaneous administration of immunostimulants.
Overdose
Oral administration of 20 g of acyclovir did not lead to the development of specific symptoms.
There may be side effects from the CNS - convulsions, tremors, lethargy.
If you overdose after ingestion, you should induce vomiting (preferably within 30 minutes after taking the drug) and take adsorbents.
In case of acute renal failure and anuria: maintenance of vital functions, hemodialysis.
Deystvuyuschee substances
acyclovir
Pharmacy terms of delivery
Prescription
The dosage form of
tablet
Appointment of
Children by doctor's appointment, Adults by doctor's appointment, Pregnant doctor's appointment, Children over 3 years of age
Indications Colds, Herpes
Possible product names
ATSIKLOVIR BELUPO 0.4 N35 TABLE P / O
Acyclovir Belupo tab p / o 400mg x 35
Acyclovir BELUPO TAB. P.P.O. 400MG No. 35
ACYCLOVIR BELUPO TAB. PO / FILM 400MG No. 35
Acyclovir Belupo tablets 400 mg, 35 pcs.
Tablets.
35rd
packaging
headlightmacrological effect of
Acyclovir is an antiviral drug, a synthetic analogue of the acyclic purine nucleoside, which has a highly selective effect on herpes viruses. Inside the virus-infected cells, a series of sequential reactions of the transformation of acyclovir into acyclovir mono-, di- and triphosphate undergoes a viral thymidine kinase. Acyclovir triphosphate is integrated into the chain of viral DNA and blocks its synthesis through competitive inhibition of viral DNA polymerase.
In vitro, acyclovir is effective against herpes simplex virus - Herpes simplex type I and II, against Varicella zoster virus higher concentrations are required to inhibit Epstein-Barr virus.
In vivo acyclovir is therapeutically and prophylactically effective primarily for viral infections caused by Herpes simplex.
Indications
Treatment of infections of the skin and mucous membranes, caused by Herpes simplex virus types 1 and 2, both primary and secondary, including genital herpes
prevention of exacerbations of recurrent infections caused by Herpes simplex virus types 1 and 2 in patients with normal immune status
prevention of primary and recurrent infections caused by Herpes simplex virus Types 1 and 2, in patients with
immunodeficiency as part of complex therapy in patients with severe immunodeficiency: with HIV infection (AIDS stage, early clinical manifestations and an expanded clinical picture) and in patients transplantation of bone marrow transplantation
treatment of primary and recurrent infections caused by the Varicella zoster virus (chickenpox, shingles).
Contraindications
- Hypersensitivity to acyclovir, ganciclovir, famciclovir, Valaciclovir or any auxiliary substance of the drug Acyclovir Belupo
- lactation period
- children's age up to 3 years (for this dosage form).
Precautions: dehydration, renal failure, neurological disorders, including in the anamnesis.
Use during pregnancy and lactation
Use during pregnancy is only possible if the intended benefit to the mother outweighs the potential risk to the fetus.
If you need to use the drug during lactation, you should stop breastfeeding.
Special instructions
Prolonged or repeated treatment with acyclovir of patients with reduced immunity can lead to the appearance of strains of viruses that are insensitive to its action. Apply strictly as prescribed by the doctor to avoid complications in adults and children over 3 years old.
Use with caution in patients with impaired renal function, elderly patients due to an increase in the half-life of acyclovir.
When using the drug Acyclovir Belupo, it is necessary to ensure the flow of a sufficient amount of fluid.
When taking the drug, kidney function (blood urea and blood plasma creatinine) should be monitored.
Acyclovir does not prevent sexual transmission of herpes, therefore during treatment it is necessary to refrain from sexual intercourse, even in the absence of clinical manifestations.
Composition of
1 tab: - acyclovir 400 mg
Excipients:
povidone,
carboxymethyl starch sodium,
microcrystalline cellulose,
silicon dioxide colloidal, srdlpp magnesium.
Shell composition:
Opadry Pink OY-24926 (hypromellose, titanium dioxide, macrogol, red iron oxide, yellow iron oxide).
Dosage and Administration
Inside.
Treatment should be started as soon as possible, immediately after the onset of the first symptoms of the disease.
The dosage regimen is set individually, depending on the severity of the disease.
In the treatment of infections of the skin and mucous membranes caused by Herpes simplex type I and II, for adults and children over 3 years of age, the drug Acyclovir Belupo is prescribed 200 mg 5 times / day. for 5 days at 4-hour intervals throughout the day and with an 8-hour interval at night. In more severe cases of the disease, the course of treatment can be extended as prescribed by the doctor.
As part of complex therapy for severe immunodeficiency, including the expanded clinical picture of HIV infection (including the early clinical manifestations of HIV infection and the stage of AIDS), 400 mg 5 times / day are prescribed after bone marrow implantation.
For the prevention of relapse of infections caused by Herpes simplex viruses type I and II, patients with normal immune status and with relapse are prescribed 200 mg 4 times / day. every 6 hours
For the prevention of infections caused by Herpes simplex viruses type I and II, adults and children older than 3 years with immunodeficiency, the drug Acyclovir Belupo is recommended to appoint 200 mg 4 times / day. every 6 hours, the maximum dose is up to 400 mg of acyclovir 5 times / day. depending on the severity of the infection.
In the treatment of infections caused by Varicella zoster, adults are prescribed 800 mg 5 times / day. every 4 hours during the day and with an 8-hour interval at night. The duration of treatment is 7-10 days. Children over 3 years of age are prescribed 20 mg / kg 4 times / day. within 5 days, for children weighing more than 40 kg, the drug is prescribed in the same dosage as adults.
In the treatment of infections caused by Herpes zoster, adults are prescribed 800 mg 4 times a day every 6 hours for 5 days.
In patients with impaired renal function: In the treatment and prevention of infections caused by Herpes simplex, in patients with CC less than 10 ml / min, the dose should be reduced to 200 mg 2 times / day. at 12 hour intervals.
In the treatment of infections caused by Varicella zoster in patients with CC less than 10 ml / min, it is recommended to reduce the dose to 800 mg 2 times / day. with 12-hour intervals with CC up to 25 ml / min, 800 mg are prescribed 3 times / day. at 8 hour intervals.
The drug Acyclovir Belupo is taken during or immediately after a meal and washed down with a sufficient amount of water.
Side effects
The drug Acyclovir Belupo is usually well tolerated.
From the digestive system: in isolated cases - abdominal pain, nausea, vomiting, diarrhea.
On the part of laboratory indicators: a slight increase in the activity of liver enzymes, rarely - a slight increase in the levels of urea and creatinine, hyperbilirubinemia, leukopenia, erythropenia.
From the side of the central nervous system and peripheral nervous system: rarely - headache, weakness in some cases - tremors, dizziness, increased fatigue, drowsiness, confusion, hallucinations, paresthesia, agitation.
Allergic reactions: anaphylactic reactions, skin allergic reactions (pruritus, Lyell's syndrome, urticaria, erythema multiforme exudative, incl. Stevens-Johnson syndrome), peripheral edema.
Other: rarely - alopecia, fever, myalgia, visual impairment, lymphadenopathy.
Drug Interactions
Concomitant use with probenecid leads to an increase in the average half-life and a decrease in clearance of acyclovir.
Concomitant use with nephrotoxic drugs increases the risk of impaired renal function.
Strengthening of the effect is noted with the simultaneous administration of immunostimulants.
Overdose
Oral administration of 20 g of acyclovir did not lead to the development of specific symptoms.
There may be side effects from the CNS - convulsions, tremors, lethargy.
If you overdose after ingestion, you should induce vomiting (preferably within 30 minutes after taking the drug) and take adsorbents.
In case of acute renal failure and anuria: maintenance of vital functions, hemodialysis.
Deystvuyuschee substances
acyclovir
Pharmacy terms of delivery
Prescription
The dosage form of
tablet
Appointment of
Children by doctor's appointment, Adults by doctor's appointment, Pregnant doctor's appointment, Children over 3 years of age
Indications Colds, Herpes
Possible product names
ATSIKLOVIR BELUPO 0.4 N35 TABLE P / O
Acyclovir Belupo tab p / o 400mg x 35
Acyclovir BELUPO TAB. P.P.O. 400MG No. 35
ACYCLOVIR BELUPO TAB. PO / FILM 400MG No. 35
Acyclovir Belupo tablets 400 mg, 35 pcs.
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