Actitropil tablets 100mg, No. 30

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BIDL3179383
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Expiration Date: 11/2025

Russian Pharmacy name:

Актитропил таблетки 100мг, №30

Actitropil tablets 100mg, No. 30

  • Diseases of the central nervous system of various origins, especially diseases of vascular origin or associated with metabolic disorders in the brain and intoxication (in particular, with post-traumatic conditions and the phenomena of chronic cerebrovascular insufficiency), accompanied by a deterioration in intellectual and mnestic functions, a decrease in motor activity;

  • neurotic conditions, manifested by lethargy, increased exhaustion, decreased psychomotor activity, impaired attention, memory impairment;

  • violations of learning processes;

  • depression of mild to moderate severity;

  • psychoorganic syndromes, manifested by intellectual-mnestic disorders and apathetic-abulic symptoms, as well as sluggish states in schizophrenia;

  • convulsive conditions;

  • obesity (alimentary-constitutional genesis);

  • prevention of hypoxia, increasing resistance to stress;

  • correction of the functional state of the body in extreme conditions of professional activity in order to prevent the development of fatigue and increase mental and physical performance;

  • correction of the daily biorhythm, regulation of the sleep-wake cycle;

  • chronic alcoholism (in order to reduce the symptoms of asthenia, depression, intellectual-mnestic disorders).

Inside.

Take immediately after meals. The dose and duration of treatment must be determined by the physician. Doses vary depending on the characteristics of the patient's condition. The average single dose is 150 mg (100 to 250 mg); the average daily dose is 250 mg (from 200 to 300 mg). The maximum allowable dose is 750 mg / day. It is recommended to take a daily dose of up to 100 mg once in the morning, and over 100 mg should be divided into 2 doses. The duration of treatment can vary from 2 weeks to 3 months, with an average of 30 days. If necessary, the course can be repeated after 1 month.

To increase efficiency - 100-200 mg once in the morning, for 2 weeks (for athletes, 3 days) The recommended duration of treatment for patients with alimentary-constitutional obesity is 30-60 days at a dose of 100-200 mg once a day (in morning hours). It is not recommended to take the drug later than 15 hours.

Tablets from white to white with a yellowish or brownish tinge, flat-cylindrical, with a chamfer and a risk on one side, marbling is allowed.

1 tab.

fonturacetam 100 mg

Excipients: microcrystalline cellulose 101 - 18 mg, povidone K17 - 40 mg, hyprolose - 20 mg, sodium bicarbonate - 20 mg, stearic acid - 2 mg. 10 pieces. - packaging

  • Childhood,

  • pregnancy,

  • lactation period (breastfeeding),

  • hypersensitivity to phonylpiracetam.

pharmachologic effect

Nootropic agent. It has a pronounced antiamnesic effect, activates the integrative activity of the brain, promotes the consolidation of memory, improves concentration and mental activity, facilitates learning processes, accelerates the transfer of information between the cerebral hemispheres, increases the resistance of brain tissue to hypoxia and toxic effects, has an anticonvulsant effect and anxiolytic activity , regulates the processes of activation and inhibition of the central nervous system, improves mood.

It has a positive effect on metabolic processes and blood circulation in the brain, stimulates redox processes, increases the energy potential of the body by utilizing glucose, and improves regional blood flow in ischemic areas of the brain. Increases the content of norepinephrine, dopamine and serotonin in the brain.

Does not affect the level of GABA content, does not bind to GABAA and GABAB receptors, does not significantly affect the spontaneous bioelectric activity of the brain.

Has no effect on the respiratory and cardiovascular systems. It has a mild diuretic effect. It has anorexigenic activity when used as a course.

It has a moderately activating effect in relation to motor reactions, increases physical performance, has a pronounced antagonism in relation to the cataleptic action of neuroleptics, reduces the severity of the hypnotic effect of ethanol and hexenal.

The psychostimulating effect prevails in the ideational sphere. The moderate psychoactivating effect of the drug is combined with anxiolytic activity; improves mood, has an analgesic effect, increasing the threshold of pain sensitivity.

It has an adaptogenic effect, increasing the body's resistance to stress under conditions of increased mental and physical stress, with fatigue, hypokinesia and immobilization, at low temperatures.

Against the background of the use of the drug, there is an improvement in vision (an increase in acuity, brightness and fields of vision); improves blood supply to the lower extremities.

Stimulates the production of antibodies in response to the introduction of an antigen, which indicates its immunostimulating properties, but at the same time does not cause the development of immediate hypersensitivity reactions and does not change the allergic inflammatory reaction of the skin caused by the introduction of a foreign protein.

The effect is manifested after a single dose, which is important when used in extreme conditions.

Pharmacokinetics

After oral administration, it is rapidly absorbed from the gastrointestinal tract, distributed in various organs and tissues, and easily penetrates the BBB. The absolute bioavailability of the drug when taken orally is 100%. Cmax in the blood is reached after 1 hour. It is not metabolized in the body and is excreted unchanged. About 40% is excreted in the urine, 60% - in the bile and sweat. T1 / 2 is 3-5 hours.

Side effect

From the side of the central nervous system: insomnia (when taking the drug after 15 hours).

In some patients, in the first 3 days of admission - psychomotor agitation, hyperemia of the skin, a feeling of warmth, increased blood pressure.

Application during pregnancy and lactation

Should not be prescribed during pregnancy and lactation (breastfeeding) due to the lack of clinical trial data; does not have teratogenic, mutagenic and embryotoxic effects.

Application for violations of liver function

With caution in patients with severe organic liver damage.

Application for impaired renal function

With caution in patients with severe organic kidney damage.

Application in children

The drug is contraindicated for use in children and adolescents under the age of 18 years.

Use in elderly patients

Use with caution in elderly patients in order to avoid aggravating the course of concomitant diseases.

special instructions

It should be used with caution in patients with severe organic lesions of the liver and kidneys, severe arterial hypertension, with severe atherosclerosis; patients who have previously suffered panic attacks, acute psychotic conditions, accompanied by psychomotor agitation (as an exacerbation of anxiety, panic, hallucinations and delirium is possible); in patients prone to allergic reactions to nootropic drugs of the pyrrolidone group.

It should be borne in mind that with excessive psychoemotional exhaustion against the background of chronic stress and fatigue, chronic insomnia, a single intake of fonturacetam on the first day can cause a sharp need for sleep.

Drug interactions

May enhance the effect of drugs that stimulate the central nervous system, antidepressants and nootropic drugs.

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