Acnecutan capsules 8mg, No. 30

severe forms of acne (nodular-cystic, conglobate, with the risk of scarring);

acne that is not amenable to other types of therapy.

Inside, preferably with meals, 1-2 times a day.

The therapeutic efficacy of Acnecutan and its side effects depend on the dose and vary in different patients. This makes it necessary to individually select the dose during treatment.

The initial dose of the drug Aknekutan is 0.4 mg / kg / day, in some cases - up to 0.8 mg / kg / day. In severe forms of the disease or patients with acne of the trunk, a dose of up to 2 mg / kg / day may be required.

The optimal course cumulative dose is 100Ц120 mg / kg. Complete remission is usually achieved within 16-24 weeks. If the recommended dose is poorly tolerated, treatment can be continued with a lower dose, but for a longer period.

In most patients, acne disappears completely after a single course of treatment.

In case of relapse, it is possible to carry out a second course of treatment at the same daily and cumulative dose. A repeated course is prescribed no earlier than 8 weeks after the first one, because improvement may be delayed.

In severe chronic renal failure, the initial dose should be reduced to 8 mg / day.

hypersensitivity to the drug or its components;

liver failure;

hypervitaminosis A;

severe hyperlipidemia;

concomitant tetracyclines therapy;

pregnancy, established and planned (possibly teratogenic and embryotoxic effect);

lactation period;

children under 12 years of age.

With care: diabetes mellitus, a history of depression, obesity, lipid metabolism disorders, alcoholism.