Tyoktovaya acid | Oktolipen concentrate for prigot.r-ra for infusions of 30 mg / ml of 10 ml of an ampoule of 10 pieces.
Special Price
$21.34
Regular Price
$29.00
In stock
SKU
BID465128
Latin name
Octolipen
Octolipen
Latin name
Octolipen
Packing
10 ampoules of 10 ml.
Pharmacological action
Oktolipen - a metabolic agent, is an endogenous antioxidant that binds free radicals.
Thioctic acid is formed in the body by oxidative decarboxylation of alpha-keto acids. As a coenzyme of mitochondrial multienzyme complexes, it participates in the oxidative decarboxylation of pyruvic acid and alpha-keto acids.
Oktolipen helps to lower blood glucose and increase glycogen in the liver, as well as overcome insulin resistance. By the nature of the biochemical action, thioctic acid is close to B vitamins. Participates in the regulation of lipid and carbohydrate metabolism, stimulates cholesterol metabolism, and improves liver function.
Oktolipen has a hepatoprotective, lipid-lowering, hypocholesterolemic, hypoglycemic effect. Improves trophic neurons and axonal conduction, reduces the manifestations of diabetic and alcoholic polyneuropathy.
Indications
Diabetic polyneuropathy alcoholic polyneuropathy.
Contraindications
pregnancy
period of breastfeeding
children and adolescents under 18 years of age (efficacy and safety of use have not been established)
hypersensitivity to the components of Oktolipen.
Use during pregnancy and lactation
Use of the drug during pregnancy is contraindicated in the absence of sufficient clinical experience with thioctic acid during pregnancy.
Reproductive toxicity studies have not identified fertility risks, fetal development effects, or any embryotoxic properties of the drug.
The use of the drug OktolipenВ® during lactation is contraindicated in the absence of data on the penetration of thioctic acid into breast milk.
Composition
Active ingredient: thioctic (? -lipoic) acid 300 mg
Dosage and administration of
oktolipen should be administered intravenously in a dose of 300-600 mg 1 time / day for 2-4 weeks. Subsequently, they switch to oral therapy.
Side effects
From the digestive system: symptoms of dyspepsia (including nausea, vomiting, heartburn).
Metabolism: symptoms of hypoglycemia (due to improved glucose uptake).
Allergic reactions: urticaria, systemic allergic reactions (including anaphylactic shock).
Drug Interaction
When administered with insulin and oral hypoglycemic agents, an increase in hypoglycemic effect is observed.
After morning intake of thioctic acid, iron, magnesium, as well as dairy products (because of their calcium content), it is recommended to take after lunch or in the evening.
Ethanol reduces the therapeutic effectiveness of thioctic acid.
Overdose
Symptoms: headache, nausea, vomiting. In severe cases (when receiving thioctic acid at a dose of 10-40 g or more than 10 tablets. 600 mg for adults, or at a dose> 50 mg / kg in children) - psychomotor excitation or clouding of consciousness, generalized convulsions, severe disorders of acid- alkaline equilibrium with lactic acidosis, hypoglycemia (up to the development of coma), acute skeletal muscle necrosis, hemolysis, DVS, suppression of bone marrow activity, multiple organ failure.
Treatment: Immediate hospitalization and application of measures in accordance with the general principles adopted in the case of accidental poisoning (including induction of vomiting, gastric lavage, intake of activated charcoal) is recommended if a significant drug overdose is suspected. Treatment of generalized seizures, lactic acidosis and other life-threatening effects of intoxication should be carried out in accordance with the principles of modern intensive care and be symptomatic. There is no specific antidote for the drug. Hemodialysis, hemoperfusion or filtration methods with the forced removal of thioctic acid from the body are ineffective.
Storage conditions
In the dark place at a temperature of no higher than 20 РC.
Expiration
2 Year
Conditions of supply of pharmacies
Prescription
dosage form
dosage form
infusion solution
Octolipen
Packing
10 ampoules of 10 ml.
Pharmacological action
Oktolipen - a metabolic agent, is an endogenous antioxidant that binds free radicals.
Thioctic acid is formed in the body by oxidative decarboxylation of alpha-keto acids. As a coenzyme of mitochondrial multienzyme complexes, it participates in the oxidative decarboxylation of pyruvic acid and alpha-keto acids.
Oktolipen helps to lower blood glucose and increase glycogen in the liver, as well as overcome insulin resistance. By the nature of the biochemical action, thioctic acid is close to B vitamins. Participates in the regulation of lipid and carbohydrate metabolism, stimulates cholesterol metabolism, and improves liver function.
Oktolipen has a hepatoprotective, lipid-lowering, hypocholesterolemic, hypoglycemic effect. Improves trophic neurons and axonal conduction, reduces the manifestations of diabetic and alcoholic polyneuropathy.
Indications
Diabetic polyneuropathy alcoholic polyneuropathy.
Contraindications
pregnancy
period of breastfeeding
children and adolescents under 18 years of age (efficacy and safety of use have not been established)
hypersensitivity to the components of Oktolipen.
Use during pregnancy and lactation
Use of the drug during pregnancy is contraindicated in the absence of sufficient clinical experience with thioctic acid during pregnancy.
Reproductive toxicity studies have not identified fertility risks, fetal development effects, or any embryotoxic properties of the drug.
The use of the drug OktolipenВ® during lactation is contraindicated in the absence of data on the penetration of thioctic acid into breast milk.
Composition
Active ingredient: thioctic (? -lipoic) acid 300 mg
Dosage and administration of
oktolipen should be administered intravenously in a dose of 300-600 mg 1 time / day for 2-4 weeks. Subsequently, they switch to oral therapy.
Side effects
From the digestive system: symptoms of dyspepsia (including nausea, vomiting, heartburn).
Metabolism: symptoms of hypoglycemia (due to improved glucose uptake).
Allergic reactions: urticaria, systemic allergic reactions (including anaphylactic shock).
Drug Interaction
When administered with insulin and oral hypoglycemic agents, an increase in hypoglycemic effect is observed.
After morning intake of thioctic acid, iron, magnesium, as well as dairy products (because of their calcium content), it is recommended to take after lunch or in the evening.
Ethanol reduces the therapeutic effectiveness of thioctic acid.
Overdose
Symptoms: headache, nausea, vomiting. In severe cases (when receiving thioctic acid at a dose of 10-40 g or more than 10 tablets. 600 mg for adults, or at a dose> 50 mg / kg in children) - psychomotor excitation or clouding of consciousness, generalized convulsions, severe disorders of acid- alkaline equilibrium with lactic acidosis, hypoglycemia (up to the development of coma), acute skeletal muscle necrosis, hemolysis, DVS, suppression of bone marrow activity, multiple organ failure.
Treatment: Immediate hospitalization and application of measures in accordance with the general principles adopted in the case of accidental poisoning (including induction of vomiting, gastric lavage, intake of activated charcoal) is recommended if a significant drug overdose is suspected. Treatment of generalized seizures, lactic acidosis and other life-threatening effects of intoxication should be carried out in accordance with the principles of modern intensive care and be symptomatic. There is no specific antidote for the drug. Hemodialysis, hemoperfusion or filtration methods with the forced removal of thioctic acid from the body are ineffective.
Storage conditions
In the dark place at a temperature of no higher than 20 РC.
Expiration
2 Year
Conditions of supply of pharmacies
Prescription
dosage form
dosage form
infusion solution
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