Sehyfenadyn | Histan-Hro 0.1% 10f1 pf32 1010 dfrew 10% Histafen tablets 50 mg, 20 pcs.
Special Price
$26.19
Regular Price
$35.00
In stock
SKU
BID463574
Release form
Tablets are white or almost white in color, round, flat-cylindrical, with bevel and notch.
Tablets are white or almost white in color, round, flat-cylindrical, with bevel and notch.
Release form
Tablets are white or almost white in color, round, flat-cylindrical, with bevel and notch.
Packaging
In 1 blister pack 10 tablets. In a cardboard bundle 2 packs.
Pharmacological action
Blocker of histamine H1 receptors with antiserotonin activity. Moderately blocks serotonin 5HT1 receptors, weakening the effects of histamine and serotonin allergy mediators. Histamine causes the clinical manifestations of allergic inflammation: edema (capillary permeability increases), flushing of the skin (vasodilation), skin itching and pain.
The peculiarity of sechifenadine is that it has an antihistamine effect not only blocking histamine H1 receptors, but also reducing the histamine content in tissues by accelerating its destruction by diamine oxidase.
In allergic diseases, the level of serotonin in the blood also rises. Serotonin increases blood pressure, causes bronchospasm, increases capillary permeability, enhances the action of inflammatory mediators - histamine, bradykinin, prostaglandins. Sechifenadine prevents or weakens the spasmogenic effect of histamine and serotonin on the smooth muscles of the bronchi, intestines, and vessels, impaired capillary permeability and the development of edema.
Sechifenadine has a pronounced antipruritic and antiexudative effect of a prolonged nature.
Affects the immunological reactivity of the body, reducing the number of B-lymphocytes in the spleen, bone marrow, lymph nodes, and also reduces the increased concentration of immunoglobulins of classes A and G.
slightly penetrates the BBB, which explains the absence of a pronounced inhibitory effect on the central nervous system, however, in some In cases of individual hypersensitivity, a slight sedative effect is observed.
When taking sechifenadine, changes in the biochemical parameters of blood and urine are not observed, the drug does not affect blood pressure, ECG, glucose and cholesterol in the blood, does not affect EEG.
Indications
- allergic rhinitis
- allergic conjunctivitis
- hay fever
- urticaria
- Quincke's edema
- allergic pruritus dermatoses (including atopic dermatitis treatment of the period and the course of the treatment of the sores with dermatitis)
Contraindications
- bronchial asthma
- pregnancy
- lactation (breastfeeding)
- children and adolescents under 18 years old
- simultaneous use of MAO inhibitors
- increased sensitivity to the components of the drug
tablets therefore, the drug should not be used for lactase deficiency, rare hereditary lactose intolerance or glucose-galactose malabsorption.
With caution, the drug should be used for impaired renal function, severe diseases of the cardiovascular system, gastrointestinal tract, liver.
Use during pregnancy and lactation
Use of the drug during pregnancy and lactation (breastfeeding) is contraindicated.
Special instructions
There are no clinical studies on the use of the drug in children and patients of senile (more than 70 years) age.
Sechifenadine tablets can be combined with topical preparations (ointment, eye drops, nose drops).
In most cases, drowsiness decreases or disappears after 2-5 days from the start of treatment.
Influence on the ability to drive vehicles and control mechanisms
Patients whose work requires quick psychomotor reactions (including drivers of vehicles) during the treatment period should refrain from driving vehicles and engaging in potentially dangerous activities.
Composition
1 tab.
sechifenadine (in the form of hydrochloride) 50 mg
Excipients: lactose monohydrate - 302 mg, microcrystalline cellulose - 20 mg, corn starch - 20 mg, silicon dioxide - 2 mg, magnesium stearate - 6 mg.
Dosage and administration of
The drug should be taken orally after a meal with water.
Adults with acute and chronic allergic diseases are prescribed 50-100 mg 2-3 times / day. Usually, the therapeutic effect occurs 3 days after the start of treatment. The duration of treatment is 5-15 days.
In order to prevent allergic diseases before the period of their seasonal exacerbation and for maintenance therapy, 50 mg 2 times / day are prescribed. It is recommended to start taking the drug 2 weeks before the expected exposure to a seasonal allergen.
Side effects of the
From the digestive system: dry mouth, epigastric pain, dyspepsia, increased appetite.
From the side of the central nervous system: headache, drowsiness when used in high doses, agitation, insomnia are possible.
Other: rarely - leukopenia, menstrual irregularities, increased urination.
Drug Interactions
Sechifenadine does not enhance the inhibitory effect of sleeping pills and alcohol on the central nervous system, but alcohol should be avoided during treatment.
Overdose
Symptoms: dry mucous membranes, headache, vomiting, abdominal pain.
Treatment: symptomatic therapy. The antidote is unknown.
Storage Conditions
The product should be stored out of reach of children, protected from light at a temperature not exceeding 25 РC.
Shelf life
4 years.
Deystvuyushtee substance
Sehifenadin
Terms and conditions
prescription
dosage form
tablets
Appointment
Appointment
Adult, Adults doctor's prescription
Tablets are white or almost white in color, round, flat-cylindrical, with bevel and notch.
Packaging
In 1 blister pack 10 tablets. In a cardboard bundle 2 packs.
Pharmacological action
Blocker of histamine H1 receptors with antiserotonin activity. Moderately blocks serotonin 5HT1 receptors, weakening the effects of histamine and serotonin allergy mediators. Histamine causes the clinical manifestations of allergic inflammation: edema (capillary permeability increases), flushing of the skin (vasodilation), skin itching and pain.
The peculiarity of sechifenadine is that it has an antihistamine effect not only blocking histamine H1 receptors, but also reducing the histamine content in tissues by accelerating its destruction by diamine oxidase.
In allergic diseases, the level of serotonin in the blood also rises. Serotonin increases blood pressure, causes bronchospasm, increases capillary permeability, enhances the action of inflammatory mediators - histamine, bradykinin, prostaglandins. Sechifenadine prevents or weakens the spasmogenic effect of histamine and serotonin on the smooth muscles of the bronchi, intestines, and vessels, impaired capillary permeability and the development of edema.
Sechifenadine has a pronounced antipruritic and antiexudative effect of a prolonged nature.
Affects the immunological reactivity of the body, reducing the number of B-lymphocytes in the spleen, bone marrow, lymph nodes, and also reduces the increased concentration of immunoglobulins of classes A and G.
slightly penetrates the BBB, which explains the absence of a pronounced inhibitory effect on the central nervous system, however, in some In cases of individual hypersensitivity, a slight sedative effect is observed.
When taking sechifenadine, changes in the biochemical parameters of blood and urine are not observed, the drug does not affect blood pressure, ECG, glucose and cholesterol in the blood, does not affect EEG.
Indications
- allergic rhinitis
- allergic conjunctivitis
- hay fever
- urticaria
- Quincke's edema
- allergic pruritus dermatoses (including atopic dermatitis treatment of the period and the course of the treatment of the sores with dermatitis)
Contraindications
- bronchial asthma
- pregnancy
- lactation (breastfeeding)
- children and adolescents under 18 years old
- simultaneous use of MAO inhibitors
- increased sensitivity to the components of the drug
tablets therefore, the drug should not be used for lactase deficiency, rare hereditary lactose intolerance or glucose-galactose malabsorption.
With caution, the drug should be used for impaired renal function, severe diseases of the cardiovascular system, gastrointestinal tract, liver.
Use during pregnancy and lactation
Use of the drug during pregnancy and lactation (breastfeeding) is contraindicated.
Special instructions
There are no clinical studies on the use of the drug in children and patients of senile (more than 70 years) age.
Sechifenadine tablets can be combined with topical preparations (ointment, eye drops, nose drops).
In most cases, drowsiness decreases or disappears after 2-5 days from the start of treatment.
Influence on the ability to drive vehicles and control mechanisms
Patients whose work requires quick psychomotor reactions (including drivers of vehicles) during the treatment period should refrain from driving vehicles and engaging in potentially dangerous activities.
Composition
1 tab.
sechifenadine (in the form of hydrochloride) 50 mg
Excipients: lactose monohydrate - 302 mg, microcrystalline cellulose - 20 mg, corn starch - 20 mg, silicon dioxide - 2 mg, magnesium stearate - 6 mg.
Dosage and administration of
The drug should be taken orally after a meal with water.
Adults with acute and chronic allergic diseases are prescribed 50-100 mg 2-3 times / day. Usually, the therapeutic effect occurs 3 days after the start of treatment. The duration of treatment is 5-15 days.
In order to prevent allergic diseases before the period of their seasonal exacerbation and for maintenance therapy, 50 mg 2 times / day are prescribed. It is recommended to start taking the drug 2 weeks before the expected exposure to a seasonal allergen.
Side effects of the
From the digestive system: dry mouth, epigastric pain, dyspepsia, increased appetite.
From the side of the central nervous system: headache, drowsiness when used in high doses, agitation, insomnia are possible.
Other: rarely - leukopenia, menstrual irregularities, increased urination.
Drug Interactions
Sechifenadine does not enhance the inhibitory effect of sleeping pills and alcohol on the central nervous system, but alcohol should be avoided during treatment.
Overdose
Symptoms: dry mucous membranes, headache, vomiting, abdominal pain.
Treatment: symptomatic therapy. The antidote is unknown.
Storage Conditions
The product should be stored out of reach of children, protected from light at a temperature not exceeding 25 РC.
Shelf life
4 years.
Deystvuyushtee substance
Sehifenadin
Terms and conditions
prescription
dosage form
tablets
Appointment
Appointment
Adult, Adults doctor's prescription
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