Paracetamol, Naproxen, Caffeine, Drotaverin, Pheniramine | Pentalgin tablets, 12 pcs.
Special Price
$15.52
Regular Price
$23.00
In stock
SKU
BID465595
Latin name
Pentalgin
Pentalgin
Latin name
Pentalgin
Release form
Coated tablets.
Pharmacological action
Combined drug, has analgesic, antipyretic and anti-inflammatory effect.
Drotaverine - has a myotropic antispasmodic effect due to the inhibition of phosphodiesterase IV, acts on smooth muscles in the gastrointestinal tract, biliary tract, genitourinary and vascular systems.
Pheniramine is a H1-histamine receptor blocker. It has an antispasmodic and mild sedative effect, reduces the effects of exudation, and also enhances the analgesic effect of paracetamol and naproxen.
Paracetamol is a non-narcotic analgesic that has an antipyretic and analgesic effect due to the blockade of cyclooxygenase in the central nervous system and the effect on the centers of pain and thermoregulation.
Naproxen is a non-steroidal anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic effects, associated with the non-selective suppression of cyclooxygenase activity that regulates the synthesis of prostaglandins.
Caffeine - causes the expansion of blood vessels of skeletal muscles, heart, kidneys, increases mental and physical performance, helps to eliminate fatigue and drowsiness, increases the permeability of histohematological barriers and increases the bioavailability of non-narcotic analgesics, thereby enhancing the therapeutic effect.
Has a tonic effect on the vessels of the brain.
Indications
mild to moderate pain syndrome of various origins (including joint pain, muscle pain, radiculitis, algodismenorrhea, neuralgia, headache, migraine, toothache)
fever, colds and other diseases accompanied by pain and inflammation.
Contraindications
severe liver failure
renal failure, severe
gastric ulcer and duodenal ulcer exacerbation
asthma
bronchospasm
anemia, leukopenia
state, accompanied by respiratory depression
brain injury
hypertension severe
acute myocardial myocardium
arrhythmias
intoxication
glaucoma glucose-6-phosphate dehydrogenase deficiency
children under 12 years old
increased Sensitivity to the drug.
With caution, the drug should be used for mild to moderate arterial hypertension, gastric ulcer and / or duodenal ulcer in remission, as well as in elderly patients.
Pregnancy and lactation
is contraindicated during pregnancy and lactation (breastfeeding).
Special instructions
The simultaneous use of Pentalgin with other agents containing paracetamol and / or other non-steroidal anti-inflammatory drugs, as well as agents to relieve symptoms of the common cold, flu and nasal congestion should be avoided.
When using the drug for more than 5-7 days, peripheral blood counts and the functional state of the liver should be monitored.
Paracetamol distorts the results of laboratory studies of glucose and uric acid in blood plasma.
If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study. Keep in mind that naproxen increases bleeding time.
The effect of caffeine on the central nervous system depends on the type of nervous system and can be manifested both by excitation and inhibition of higher nervous activity.
Alcohol-containing drinks should not be consumed during treatment.
In some cases, it is possible to reduce the concentration of attention and the speed of psychomotor reactions, therefore, during treatment, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.
Ingredients
1 tablet contains:
paracetamol 325 mg,
naproxen 100 mg,
caffeine drotaverina hydrochloride - 40 mg,
pheniramine maleate - 10 mg srdlkrccrcrcfcelcrycrystalline potassium, cellulose sodium,
hyprolose (hydroxypropyl cellulose (clucel EF)),
citric acid monohydrate,
butylhydroxytoluene (E 321),
magnesium stearate,
talc,
dye quinoline yellow (E 104),
indigo carmine (E 132).
Dosage and administration of
Pentalgin is taken orally 1 tablet 1-3 times a day.
The maximum daily dose is 4 tablets.
Duration of treatment is not more than 3 days as an antipyretic and not more than 5 days as an anesthetic.
Continuation of treatment with the drug is possible only after consulting a doctor.
Side effects
Allergic reactions: skin rash, itching, urticaria, angioedema
Hematopoietic organs: thrombocytopenia, leukopenia, agranulocytosis, anemia, methemoglobinemia nervousness, nervousness, srdlp increased reflexes, tremors, headache, sleep disturbances, dizziness, decreased concentration
From the cardiovascular system: palpitations, arrhythmias, increased blood pressure
From the digestive system: erosive and ulcerative lesions of the gastrointestinal tract, nausea, vomiting, epigastric discomfort, abdominal pain, constipation, impaired liver function
From the urinary system: impaired renal function
From the sensory organs: hearing loss, tinnitus, increased intraocular pressure leukemia in patients with angle-closure glaucoma
Other: dermatitis, tachypnea (rapid breathing).
Drug interaction
With the simultaneous use of drugs that have a depressing effect on the central nervous system (including sedatives and tranquilizers), an increase in the severity of the sedative effect and inhibitory effect on the respiratory center is likely. Enhances the effect of ethanol on the psychomotor reaction.
Metamizole sodium reduces the concentration of cyclosporine. Metamizole sodium, displacing oral hypoglycemic drugs, indirect anticoagulants, glucocort from a protein bondicosteroids and indomethacin, increases their activity.
Tricyclic antidepressants, oral contraceptives, allopurinol disrupt the metabolism of metamizole in the liver and increase its toxicity.
The simultaneous use of the drug with other non-narcotic analgesics may lead to increased toxic effects.
Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effect of metamizole.
Overdose
Symptoms: nausea, vomiting, gastralgia, drowsiness, tachycardia, heart rhythm disorders, delirium, weakness, respiratory depression.
Treatment: induction of vomiting, gastric lavage through a probe, appointment of adsorbents (activated charcoal), symptomatic therapy aimed at maintaining vital functions.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 РC.
Shelf life
1 year.
Deystvuyushtee substance
Paracetamol, Naproxen, Caffeine, Drotaverine, pheniramine
Terms and conditions
without prescription
tablet dosage form of tablets
Appointment
Appointment
Adult
Pharmstandard-Leksredstva, Russia
Pentalgin
Release form
Coated tablets.
Pharmacological action
Combined drug, has analgesic, antipyretic and anti-inflammatory effect.
Drotaverine - has a myotropic antispasmodic effect due to the inhibition of phosphodiesterase IV, acts on smooth muscles in the gastrointestinal tract, biliary tract, genitourinary and vascular systems.
Pheniramine is a H1-histamine receptor blocker. It has an antispasmodic and mild sedative effect, reduces the effects of exudation, and also enhances the analgesic effect of paracetamol and naproxen.
Paracetamol is a non-narcotic analgesic that has an antipyretic and analgesic effect due to the blockade of cyclooxygenase in the central nervous system and the effect on the centers of pain and thermoregulation.
Naproxen is a non-steroidal anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic effects, associated with the non-selective suppression of cyclooxygenase activity that regulates the synthesis of prostaglandins.
Caffeine - causes the expansion of blood vessels of skeletal muscles, heart, kidneys, increases mental and physical performance, helps to eliminate fatigue and drowsiness, increases the permeability of histohematological barriers and increases the bioavailability of non-narcotic analgesics, thereby enhancing the therapeutic effect.
Has a tonic effect on the vessels of the brain.
Indications
mild to moderate pain syndrome of various origins (including joint pain, muscle pain, radiculitis, algodismenorrhea, neuralgia, headache, migraine, toothache)
fever, colds and other diseases accompanied by pain and inflammation.
Contraindications
severe liver failure
renal failure, severe
gastric ulcer and duodenal ulcer exacerbation
asthma
bronchospasm
anemia, leukopenia
state, accompanied by respiratory depression
brain injury
hypertension severe
acute myocardial myocardium
arrhythmias
intoxication
glaucoma glucose-6-phosphate dehydrogenase deficiency
children under 12 years old
increased Sensitivity to the drug.
With caution, the drug should be used for mild to moderate arterial hypertension, gastric ulcer and / or duodenal ulcer in remission, as well as in elderly patients.
Pregnancy and lactation
is contraindicated during pregnancy and lactation (breastfeeding).
Special instructions
The simultaneous use of Pentalgin with other agents containing paracetamol and / or other non-steroidal anti-inflammatory drugs, as well as agents to relieve symptoms of the common cold, flu and nasal congestion should be avoided.
When using the drug for more than 5-7 days, peripheral blood counts and the functional state of the liver should be monitored.
Paracetamol distorts the results of laboratory studies of glucose and uric acid in blood plasma.
If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study. Keep in mind that naproxen increases bleeding time.
The effect of caffeine on the central nervous system depends on the type of nervous system and can be manifested both by excitation and inhibition of higher nervous activity.
Alcohol-containing drinks should not be consumed during treatment.
In some cases, it is possible to reduce the concentration of attention and the speed of psychomotor reactions, therefore, during treatment, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.
Ingredients
1 tablet contains:
paracetamol 325 mg,
naproxen 100 mg,
caffeine drotaverina hydrochloride - 40 mg,
pheniramine maleate - 10 mg srdlkrccrcrcfcelcrycrystalline potassium, cellulose sodium,
hyprolose (hydroxypropyl cellulose (clucel EF)),
citric acid monohydrate,
butylhydroxytoluene (E 321),
magnesium stearate,
talc,
dye quinoline yellow (E 104),
indigo carmine (E 132).
Dosage and administration of
Pentalgin is taken orally 1 tablet 1-3 times a day.
The maximum daily dose is 4 tablets.
Duration of treatment is not more than 3 days as an antipyretic and not more than 5 days as an anesthetic.
Continuation of treatment with the drug is possible only after consulting a doctor.
Side effects
Allergic reactions: skin rash, itching, urticaria, angioedema
Hematopoietic organs: thrombocytopenia, leukopenia, agranulocytosis, anemia, methemoglobinemia nervousness, nervousness, srdlp increased reflexes, tremors, headache, sleep disturbances, dizziness, decreased concentration
From the cardiovascular system: palpitations, arrhythmias, increased blood pressure
From the digestive system: erosive and ulcerative lesions of the gastrointestinal tract, nausea, vomiting, epigastric discomfort, abdominal pain, constipation, impaired liver function
From the urinary system: impaired renal function
From the sensory organs: hearing loss, tinnitus, increased intraocular pressure leukemia in patients with angle-closure glaucoma
Other: dermatitis, tachypnea (rapid breathing).
Drug interaction
With the simultaneous use of drugs that have a depressing effect on the central nervous system (including sedatives and tranquilizers), an increase in the severity of the sedative effect and inhibitory effect on the respiratory center is likely. Enhances the effect of ethanol on the psychomotor reaction.
Metamizole sodium reduces the concentration of cyclosporine. Metamizole sodium, displacing oral hypoglycemic drugs, indirect anticoagulants, glucocort from a protein bondicosteroids and indomethacin, increases their activity.
Tricyclic antidepressants, oral contraceptives, allopurinol disrupt the metabolism of metamizole in the liver and increase its toxicity.
The simultaneous use of the drug with other non-narcotic analgesics may lead to increased toxic effects.
Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the effect of metamizole.
Overdose
Symptoms: nausea, vomiting, gastralgia, drowsiness, tachycardia, heart rhythm disorders, delirium, weakness, respiratory depression.
Treatment: induction of vomiting, gastric lavage through a probe, appointment of adsorbents (activated charcoal), symptomatic therapy aimed at maintaining vital functions.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 РC.
Shelf life
1 year.
Deystvuyushtee substance
Paracetamol, Naproxen, Caffeine, Drotaverine, pheniramine
Terms and conditions
without prescription
tablet dosage form of tablets
Appointment
Appointment
Adult
Pharmstandard-Leksredstva, Russia
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