liofilizat juice and cyclamen extract of European fresh | Sinuforte lyophilisate for intranasal administration r-l + nozzle 50 mg 1 pc.
Special Price
$53.35
Regular Price
$63.00
In stock
SKU
BID463684
Latin name
Sinuforte
Sinuforte
Latin name
Sinuforte
Release form
Lyophilisate for preparation of solution for intranasal administration
Pharmacological action
PHARMACOTHERAPEUTIC GROUP: nasal disease treatment.
ATC CODE: R01AX
PHARMACOLOGICAL PROPERTIES
Pharmacodynamics
A herbal preparation for the treatment of inflammatory diseases of the paranasal sinuses (SNP) and nasal cavity. The drug affects sensitive trigeminal receptors in the middle nasal passage and causes reflex secretion in the mucous membrane of the nasal cavity and SNP. Stimulated hypersecretion is accompanied by a change in the rheological properties of the secretion and the normalization of its viscosity. Reflex hypersecretion in combination with the decongestant action of the drug leads to the evacuation of secretions from the sinuses to the nasopharynx and provides physiological drainage of all sinuses at the same time.
The drug helps to restore mucociliary transport in the nasal cavity and SNPs by increasing the presence of the liquid part of the secretion in the surface layer of mucus.
Sinuforte® enhances microcirculation of the blood in the nasal mucosa and SNP. This is due to the fact that parasympathetic stimulation, which activates secretion, also causes vasodilation of the vessels supplying the glands.
Enhanced reflex secretion in the form of serous-mucous secretions is detected after a few minutes and can last from 30 to 120 minutes depending on the individual characteristics of the body.
Pharmacokinetics
The effect of Sinuforte® is due to the combined effects of cyclamen components, the most studied of which are triterpene saponins. Kinetic studies are not possible since collectively the components cannot be traced using markers or bioassays. For the same reason, it is impossible to detect the metabolites of the drug.
Indications
- Comprehensive therapy of acute and chronic sinusitis: sinusitis, frontal sinusitis, ethmoiditis and sphenoiditis (in the case of purulent sinusitis, occurring with the phenomena of generalization of infection and / or orbital complications, Sinuforte® should be used only in combination with antibiotics). In the uncomplicated course of the disease, it is possible to use the drug as a monotherapy under the supervision of a doctor
- Complex therapy of rhinosinusitis accompanied by exudative otitis media
- A period of early postoperative rehabilitation after endoscopic surgery on the paranasal sinuses.
Contraindications
- Hypersensitivity to the components of the drug
- Polypous rhinosinusitis
- Cysts of the paranasal sinuses
- Allergic rhinosinusopathies
- Allergic type III-allergic reactions (delayed)
- Pregnancy and lactation (safety of use during these periods has not been studied)
- Children under 5 years of age (use in children under 5 years of age has not been studied).
Use during pregnancy and lactation
Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.
Special instructions
During postoperative rehabilitation after endoscopic surgery, SinuforteВ® is used on the second day to cleanse (rehabilitate) the paranasal sinuses and nasal cavity and reduce swelling of the mucous membrane.
When using, avoid contact with SinuforteВ® in the eyes due to the irritating effect of the drug on the mucous membrane of the eye and the possible development of the phenomena of acute conjunctivitis.
It is recommended that you hold your breath during drug administration.
Direct spraying of the drug should be done with one click with the head upright.
Consultation with an otorhinolaryngologist is recommended before use.
Composition
1 bottle Active ingredient: srdlp substance: lyophilisate juice and extract of European cyclamen tubers fresh 50 mg.
Dosage and Administration
Intranasally.
Adults and children 5 years of age and older:
Unscrew the cap from the drug vial and remove the cork.
Open the solvent bottle by breaking off the top.
Completely pour the contents of the solvent into the vial with the drug.
Screw the dispenser onto the vial and shake until drug is completely dissolved.
Remove the protective cap from the dispenser.
Perform 2-3 test sprays into the air.
With the head upright, insert the dispenser into each nasal passage, hold your breath and spray with one touch.
- With each press, the dispenser sprays 0.13 ml (2-3 drops) of the drug, which is about 1.3 mg of the drug (single dose) .- The preparation prepared by the above method is administered once a day by spraying once in each nasal passage. It is preliminary recommended to do 2-3 test sprays in air.
- The drug is recommended to be used daily, if necessary, its use every other day is also allowed.
- The duration of one course of treatment is 12-16 days with the introduction of the drug every other day or 6-8 days with daily use.
Side effects
There may be a slight or moderate burning sensation in the nasal cavity, salivary and / or lacrimation in response to irritation of the sensory trigeminal receptors.
In some cases, redness of the face, a short headache in the frontal region, or a pale pink colored discharge from the nose as a result of capillary diapedesis may appear. The above short-term physiological reactions confirm the reflex mechanism of action of the drug and do not require discontinuation of treatment.
Allergic reactions (including skin rash, shortness of breath, etc.) are possible. In these cases, it is recommended to stop taking the drug and consult a specialist.
Drug Interactions
It is necessary to refrain from prior administration, as well as the simultaneous use of local anesthetics and / or local decongestants in connection with a possible violation of the mechanism of action of the drug Sinuforte®.
If necessary, a combination of Sinuforte® with antibacterial drugs is possible and acceptable.
Interactions with other drugs have not been studied to date.
Overdose
There have been no reports of overdose with Sinuforte® at this time. Excessive single dose does not lead to an increase in the therapeutic effect and can cause a feeling of intense burning and pain in the nasopharynx.
If symptoms of overdose appear, symptomatic therapy should be performed: rinse the nasal cavity, rinse the throat with warm water and apply antihistamines.
Storage Conditions
In a dark place at a temperature not exceeding 25 РC.
Shelf life
5 years
Deystvuyushtee substance
Lyophilisate juice and эkstrakta klubney cyclamic evropeyskogo Svezhin
Terms and conditions
without prescription
dosage form
solution for intranasal administration
Appointment
Appointment
Different
Sinuforte
Release form
Lyophilisate for preparation of solution for intranasal administration
Pharmacological action
PHARMACOTHERAPEUTIC GROUP: nasal disease treatment.
ATC CODE: R01AX
PHARMACOLOGICAL PROPERTIES
Pharmacodynamics
A herbal preparation for the treatment of inflammatory diseases of the paranasal sinuses (SNP) and nasal cavity. The drug affects sensitive trigeminal receptors in the middle nasal passage and causes reflex secretion in the mucous membrane of the nasal cavity and SNP. Stimulated hypersecretion is accompanied by a change in the rheological properties of the secretion and the normalization of its viscosity. Reflex hypersecretion in combination with the decongestant action of the drug leads to the evacuation of secretions from the sinuses to the nasopharynx and provides physiological drainage of all sinuses at the same time.
The drug helps to restore mucociliary transport in the nasal cavity and SNPs by increasing the presence of the liquid part of the secretion in the surface layer of mucus.
Sinuforte® enhances microcirculation of the blood in the nasal mucosa and SNP. This is due to the fact that parasympathetic stimulation, which activates secretion, also causes vasodilation of the vessels supplying the glands.
Enhanced reflex secretion in the form of serous-mucous secretions is detected after a few minutes and can last from 30 to 120 minutes depending on the individual characteristics of the body.
Pharmacokinetics
The effect of Sinuforte® is due to the combined effects of cyclamen components, the most studied of which are triterpene saponins. Kinetic studies are not possible since collectively the components cannot be traced using markers or bioassays. For the same reason, it is impossible to detect the metabolites of the drug.
Indications
- Comprehensive therapy of acute and chronic sinusitis: sinusitis, frontal sinusitis, ethmoiditis and sphenoiditis (in the case of purulent sinusitis, occurring with the phenomena of generalization of infection and / or orbital complications, Sinuforte® should be used only in combination with antibiotics). In the uncomplicated course of the disease, it is possible to use the drug as a monotherapy under the supervision of a doctor
- Complex therapy of rhinosinusitis accompanied by exudative otitis media
- A period of early postoperative rehabilitation after endoscopic surgery on the paranasal sinuses.
Contraindications
- Hypersensitivity to the components of the drug
- Polypous rhinosinusitis
- Cysts of the paranasal sinuses
- Allergic rhinosinusopathies
- Allergic type III-allergic reactions (delayed)
- Pregnancy and lactation (safety of use during these periods has not been studied)
- Children under 5 years of age (use in children under 5 years of age has not been studied).
Use during pregnancy and lactation
Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.
Special instructions
During postoperative rehabilitation after endoscopic surgery, SinuforteВ® is used on the second day to cleanse (rehabilitate) the paranasal sinuses and nasal cavity and reduce swelling of the mucous membrane.
When using, avoid contact with SinuforteВ® in the eyes due to the irritating effect of the drug on the mucous membrane of the eye and the possible development of the phenomena of acute conjunctivitis.
It is recommended that you hold your breath during drug administration.
Direct spraying of the drug should be done with one click with the head upright.
Consultation with an otorhinolaryngologist is recommended before use.
Composition
1 bottle Active ingredient: srdlp substance: lyophilisate juice and extract of European cyclamen tubers fresh 50 mg.
Dosage and Administration
Intranasally.
Adults and children 5 years of age and older:
Unscrew the cap from the drug vial and remove the cork.
Open the solvent bottle by breaking off the top.
Completely pour the contents of the solvent into the vial with the drug.
Screw the dispenser onto the vial and shake until drug is completely dissolved.
Remove the protective cap from the dispenser.
Perform 2-3 test sprays into the air.
With the head upright, insert the dispenser into each nasal passage, hold your breath and spray with one touch.
- With each press, the dispenser sprays 0.13 ml (2-3 drops) of the drug, which is about 1.3 mg of the drug (single dose) .- The preparation prepared by the above method is administered once a day by spraying once in each nasal passage. It is preliminary recommended to do 2-3 test sprays in air.
- The drug is recommended to be used daily, if necessary, its use every other day is also allowed.
- The duration of one course of treatment is 12-16 days with the introduction of the drug every other day or 6-8 days with daily use.
Side effects
There may be a slight or moderate burning sensation in the nasal cavity, salivary and / or lacrimation in response to irritation of the sensory trigeminal receptors.
In some cases, redness of the face, a short headache in the frontal region, or a pale pink colored discharge from the nose as a result of capillary diapedesis may appear. The above short-term physiological reactions confirm the reflex mechanism of action of the drug and do not require discontinuation of treatment.
Allergic reactions (including skin rash, shortness of breath, etc.) are possible. In these cases, it is recommended to stop taking the drug and consult a specialist.
Drug Interactions
It is necessary to refrain from prior administration, as well as the simultaneous use of local anesthetics and / or local decongestants in connection with a possible violation of the mechanism of action of the drug Sinuforte®.
If necessary, a combination of Sinuforte® with antibacterial drugs is possible and acceptable.
Interactions with other drugs have not been studied to date.
Overdose
There have been no reports of overdose with Sinuforte® at this time. Excessive single dose does not lead to an increase in the therapeutic effect and can cause a feeling of intense burning and pain in the nasopharynx.
If symptoms of overdose appear, symptomatic therapy should be performed: rinse the nasal cavity, rinse the throat with warm water and apply antihistamines.
Storage Conditions
In a dark place at a temperature not exceeding 25 РC.
Shelf life
5 years
Deystvuyushtee substance
Lyophilisate juice and эkstrakta klubney cyclamic evropeyskogo Svezhin
Terms and conditions
without prescription
dosage form
solution for intranasal administration
Appointment
Appointment
Different
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