Ketoprofen | Quickgel gel 2.5%, 50 g

Release form

Gel for external use.

50 g packaging



Pharmacological action

Pharmacodynamics

NSAIDs, a derivative of propionic acid. It has an analgesic, anti-inflammatory effect.

Inhibiting COX-1 and COX-2, inhibits the synthesis of prostaglandins. It has anti-bradykinin activity, stabilizes lysosomal membranes. Reduces the release of cytokines, inhibits the activity of neutrophils.

With joint syndrome, relieves joint pain at rest and during movement, reduces morning stiffness and swelling of the joints, contributes to an increase in range of motion.

Pharmacokinetics

Absorption

When the gel is used externally, transdermal absorption of ketoprofen is extremely slow, which ensures that its concentration in the inflamed tissues remains within the therapeutic level for a long time. Absorption into the systemic circulation is negligible. Almost does not cumulate. The bioavailability of the gel is about 5%.

Distribution

Ketoprofen penetrates well into synovial fluid and connective tissue.

Indications

Inflammatory or traumatic lesions of the joints, tendons, ligaments and muscles:

arthritis, periarthritis

tendonitis, tendosynitis

bursitis

bruises, damage to ligaments, dislocations, damage to the meniscus of the knee

torticollis

lumbago.

Phlebitis, peripheralitis.

Contraindications

Hypersensitivity to ketoprofen or other components of the drug

dermatosis

eczema

infected abrasions and wounds

pregnancy and lactation

childhood.

Use during pregnancy and lactation

The drug is contraindicated in pregnancy and lactation.

Composition of

1 g of gel contains:

Active substances:

ketoprofen 25 mg.

Excipients:

ethanol (ethyl alcohol) rectified,

nipagin,

carbomer,

trometamol,

lavender oil,

neroli oil,

purified water.

Dosage and administration

The drug is applied to the skin of the painful area 2 times / day, squeezing about 3-5 cm of gel or more from the tube (depending on the area of ​​the painful area), spread in a uniform thin layer and gently rub until completely absorbed.

In order to increase the effectiveness of therapy, it is possible to use a gel under a dry occlusive dressing.

Side effects

In rare cases: allergic reactions that require discontinuation of the drug, photosensitivity.

Drug Interaction

There have been no reported drug interactions with Bystrumgel® with other drugs at this time.

Overdose

There have been no reports of overdose with Bystrumgel®.

Storage conditions

Store in a dry, dark place, out of the reach of children, at a temperature of 15 ° to 25 РC.

Expiration

2 years.

Deystvuyuschee substances

Ketoprofen

Dosage form

Dosage form

gel for external use