Ketoprofen | Ketonal solution for iv. and w / mouse. dosing 50 mg / ml 2 ml amp 50 pcs
Special Price
$33.95
Regular Price
$43.00
In stock
SKU
BID465363
Latin name
Ketonal
Ketonal
Latin name
Ketonal
release form injection solution for
Packing
50 ampoules.
Pharmacological action
Ketonal - NSAIDs, a derivative of propionic acid.
It has analgesic, anti-inflammatory and antipyretic effects.
The mechanism of action is associated with inhibition of prostaglandin synthesis at the level of cyclooxygenase.
In addition, ketoprofen inhibits lipoxygenase, has anti-bradykinin activity, stabilizes lysosomal membranes, and significantly inhibits neutrophil activity in patients with rheumatoid arthritis.
The pronounced analgesic effect of ketoprofen is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system).
Indications
symptomatic therapy of painful inflammatory processes of various origins (including postoperative and post-traumatic pains, sciatica, myalgia, radiculitis, bruises and muscle strains, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, acute attack podagitis, acute attack podagitis, acute attack podagitis, acute attack podagitis, acute attack bursitis)
symptomatic treatment of acute pain syndrome with inflammatory diseases of the musculoskeletal system (for i / m administration only)
Contraindications
gastrointestinal tract disease in the exacerbation phase
severe liver dysfunction
severe renal dysfunction
blood disorders (leukopenia, thrombocytopenia, blood coagulation system disorders) I
hematitis srdlpp hypersensitivity to ketoprofen, acetylsalicylic acid or other NSAIDs (history of bronchospasm, urticaria and rhinitis caused by acetylsalicylic acid).
Pregnancy and lactation
The use of Ketonal in the third trimester of pregnancy is contraindicated.
The use of Ketonal in the first and second trimesters of pregnancy is possible only if the potential benefit to the mother outweighs the risk to the fetus.
If you need to use Ketonal during lactation, you should decide on the termination of breastfeeding.
Composition
1 ml contains ketoprofen 50 mg (1 ampoule - 100 mg)
excipients: propylene glycol, ethanol, benzyl alcohol, sodium hydroxide, d / i water.
Dosage and administration
The solution is administered in / m or / in.
Intramuscularly administered 100 mg 1-2 times / day.
IV infusion of ketoprofen is carried out only in a hospital setting.
Short intravenous infusion: 100-200 mg, diluted in 100 ml of 0.9% sodium chloride solution, administered within 0.5-1 hours. Repeated administration after 8 hours is possible.
Continuous intravenous infusion: 100-200 mg, diluted in 500 ml of an infusion solution (0.9% sodium chloride solution, lactate-containing Ringer's solution, 5% dextrose solution), administered within 8 hours. Repeated administration after 8 hours is possible.
Maximum daily dose (including when using various dosage forms ) is 200 mg.
Overdose
Symptoms: nausea, vomiting, abdominal pain, vomiting with blood, melena, impaired consciousness, respiratory depression, convulsions, impaired renal function, renal failure.
Treatment: gastric lavage, activated charcoal administration, symptomatic therapy.
The use of histamine H 2 receptor blockers, proton pump inhibitors, and prostaglandin inhibitors has been shown. There is no specific antidote.
Storage conditions
Keep out of the reach of children at a temperature not exceeding 25 РC.
Expiration
5 years.
Deystvuyuschee substances
Ketoprofen
Conditions of supply of pharmacies
Prescription
.d., Switzerland
Ketonal
release form injection solution for
Packing
50 ampoules.
Pharmacological action
Ketonal - NSAIDs, a derivative of propionic acid.
It has analgesic, anti-inflammatory and antipyretic effects.
The mechanism of action is associated with inhibition of prostaglandin synthesis at the level of cyclooxygenase.
In addition, ketoprofen inhibits lipoxygenase, has anti-bradykinin activity, stabilizes lysosomal membranes, and significantly inhibits neutrophil activity in patients with rheumatoid arthritis.
The pronounced analgesic effect of ketoprofen is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system).
Indications
symptomatic therapy of painful inflammatory processes of various origins (including postoperative and post-traumatic pains, sciatica, myalgia, radiculitis, bruises and muscle strains, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, acute attack podagitis, acute attack podagitis, acute attack podagitis, acute attack podagitis, acute attack bursitis)
symptomatic treatment of acute pain syndrome with inflammatory diseases of the musculoskeletal system (for i / m administration only)
Contraindications
gastrointestinal tract disease in the exacerbation phase
severe liver dysfunction
severe renal dysfunction
blood disorders (leukopenia, thrombocytopenia, blood coagulation system disorders) I
hematitis srdlpp hypersensitivity to ketoprofen, acetylsalicylic acid or other NSAIDs (history of bronchospasm, urticaria and rhinitis caused by acetylsalicylic acid).
Pregnancy and lactation
The use of Ketonal in the third trimester of pregnancy is contraindicated.
The use of Ketonal in the first and second trimesters of pregnancy is possible only if the potential benefit to the mother outweighs the risk to the fetus.
If you need to use Ketonal during lactation, you should decide on the termination of breastfeeding.
Composition
1 ml contains ketoprofen 50 mg (1 ampoule - 100 mg)
excipients: propylene glycol, ethanol, benzyl alcohol, sodium hydroxide, d / i water.
Dosage and administration
The solution is administered in / m or / in.
Intramuscularly administered 100 mg 1-2 times / day.
IV infusion of ketoprofen is carried out only in a hospital setting.
Short intravenous infusion: 100-200 mg, diluted in 100 ml of 0.9% sodium chloride solution, administered within 0.5-1 hours. Repeated administration after 8 hours is possible.
Continuous intravenous infusion: 100-200 mg, diluted in 500 ml of an infusion solution (0.9% sodium chloride solution, lactate-containing Ringer's solution, 5% dextrose solution), administered within 8 hours. Repeated administration after 8 hours is possible.
Maximum daily dose (including when using various dosage forms ) is 200 mg.
Overdose
Symptoms: nausea, vomiting, abdominal pain, vomiting with blood, melena, impaired consciousness, respiratory depression, convulsions, impaired renal function, renal failure.
Treatment: gastric lavage, activated charcoal administration, symptomatic therapy.
The use of histamine H 2 receptor blockers, proton pump inhibitors, and prostaglandin inhibitors has been shown. There is no specific antidote.
Storage conditions
Keep out of the reach of children at a temperature not exceeding 25 РC.
Expiration
5 years.
Deystvuyuschee substances
Ketoprofen
Conditions of supply of pharmacies
Prescription
.d., Switzerland
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