etylmetylhydroksypyrydyna | Mexiprim tablets coated. 125 mg 30 pcs.

Special Price $16.66 Regular Price $24.00
In stock
SKU
BID464370
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Description

Pills are round, biconvex, film-coated, from white to white with a creamy tint, at the break - from white to white with a grayish, or yellowish, or creamy tint.
Description

Pills are round, biconvex, film-coated, from white to white with a creamy tint, at the break - from white to white with a grayish, or yellowish, or creamy tint.

Latin name

Mexiprim

Release form

125 mg film-coated tablets. On 10 tablets in a blister strip packaging from a film of polyvinyl chloride and aluminum foil. 1, 2, 3, 4 or 6 blister packs along with instructions for use are placed in a cardboard box.

Packing

10 pcs - blister packs (3) - packs of cardboard.

Pharmacological action

Mexiprim refers to heteroaromatic antioxidants. It has a wide range of pharmacological activity: it increases the body's resistance to stress, has an anxiolytic effect, is not accompanied by a muscle relaxant effect, has nootropic properties, prevents and reduces learning and memory disorders that occur during aging and exposure to various pathogenic factors, has an anticonvulsant effect, exhibits antioxidant and antihypoxic properties, increases concentration attention and performance weakens the toxic effects of alcohol. The drug improves the metabolism of brain tissue and their blood supply, improves microcirculation and rheological properties of blood, reduces platelet aggregation. Stabilizes the membrane structure of blood cells (red blood cells and platelets). It has a lipid-lowering effect, reduces the content of total cholesterol and low density lipoproteins. The mechanism of action of Mexiprim is due to its antioxidant and membrane-protective action. It inhibits lipid peroxidation, increases the activity of superoxide oxidase, increases the ratio of lipid protein, reduces the viscosity of the membrane, increases its fluidity. It modulates the activity of membrane-bound enzymes (calcium-independent phosphodiesterase, adenylate cyclase, acetylcholinesterase), receptor complexes (benzodiazepine, GABA, acetylcholine), which enhances their ability to bind to ligands, helps to preserve the structurally functional organization of biomembranes, and transport neuron. Mexiprim increases the content of dopamine in the brain. It causes an increase in the compensatory activation of aerobic glycolysis and a decrease in the degree of inhibition of oxidative processes in the Krebs cycle under hypoxia with an increase in the content of ATP and creatine phosphate, activation of the energy-synthesizing functions of mitochondria, and stabilization of cell membranes.

Indications

anxiety disorders in neurotic and neurosis-like conditions, vegetative-vascular dystonia, mild cognitive disorders of various origins (in the case of psycho-organic syndrome and asthenic disorders caused by acute and chronic cerebrovascular diseases, cerebro-neuroinfection and traumatic brain injuries) memory disorders and intellectual impairment in the elderly the effects of extreme (stress ) Factors alcohol withdrawal syndrome with predominance neurosis and vegetative-vascular disorders.

Contraindications

Hepatic and / or renal failure, increased individual sensitivity to the drug, children, pregnancy, breastfeeding.

Use during pregnancy and lactation

Currently, the possibility and safety of using Mexiprim during pregnancy and lactation has not been sufficiently studied, therefore the use of the drug in this category of patients is contraindicated.

Special instructions

During treatment, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Dosage and administration of merdiprim

are prescribed orally. The therapeutic doses used and the duration of treatment are determined by the sensitivity of patients to the drug. Treatment begins with a dose of 0.25-0.5 g, the average daily dose is 0.25-0.5 g, the maximum daily dose is 0.8 g. The daily dose of the drug is distributed in 2-3 doses throughout the day. For the treatment of patients with anxiety disorders, autonomic vascular dysfunctions and cognitive impairment, Mexiprim is used for 2-6 weeks. When stopping alcohol withdrawal syndrome, Mexiprim is used within 5-7 days. Mexiprim course therapy is completed gradually, reducing the dose of the drug within 2-3 days.

Side effects

Rarely - nausea, dryness of the oral mucosa, drowsiness, allergic reactions.

Drug Interaction

Compatible with psychotropic drugs. Increases the effect of benzodiazepine anxiolytics, anticonvulsants (carbamazepine), antiparkinsonian agents (levodopa), reduces the toxic effect of ethyl alcohol.

Overdose

Symptoms: sleep disturbance (insomnia, in some cases drowsiness).

Treatment: usually not required - symptoms disappear on their own within a day. In severe cases with insomnia, it is recommended to take nitrazepam 10 mg, oxazepam 10 mg or diazepam 5 mg.

Storage conditions

In a dry, protected from light and inaccessible to children place, at a temperature not exceeding 30 РC.

Expiration

5 years. Do not use after the expiry date stated on the packaging.

Active ingredient

Ethylmethylhydroxypyridine succinate

Nizhpharm, Russia

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