Desloratadine | Lordestine tablets is covered.pl.ob. 5 mg 30 pcs.
Special Price
$29.10
Regular Price
$37.00
In stock
SKU
BID465573
Release form
Tablets.
Tablets.
Release form
Tablets.
Packing
30 pcs.
Pharmacological action
LORDESTINE - a blocker of histamine H1 receptors (long-acting). It is the primary active metabolite of loratadine.
Inhibits the release of histamine and leukotriene C4 from mast cells.
Prevents development and facilitates the course of allergic reactions. It has anti-allergic, antipruritic and anti-exudative action.
Reduces the permeability of capillaries, prevents the development of tissue edema, relieves spasm of smooth muscles.
Almost no sedative effect and when taken in a dose of 7.5 mg does not affect the speed of psychomotor reactions.
In comparative studies of desloratadine and loratadine, there were no qualitative or quantitative differences in the toxicity of the two drugs in comparable doses (taking into account the concentration of desloratadine).
Indications
Seasonal allergic rhinitis, chronic idiopathic urticaria.
Contraindications
Pregnancy, lactation, children under 2 years of age, hypersensitivity to desloratadine.
Special instructions
Influence on the ability to drive vehicles and control mechanisms
No effect of Lordestine when used in recommended doses on the ability to drive vehicles and control mechanisms. However, given that patients may experience drowsiness, caution is advised in case of side effects from the central nervous system.
Composition
Active ingredient:
desloratadine hemisulphate 5.788 (equivalent to 5 mg of desloratadine)
Excipients:
MCC - 39 mg
calcium hydrogen phosphate dihydrate - 46.712 mg
starch pregelatinized - 7 mg
silicon aerosol mgloid - colloid mgloid 1
Film sheath:
Opadry AMB yellow 80W22099 (partially hydrolyzed polyvinyl alcohol, titanium dioxide, talc, lecithin, quinoline yellow dye-based aluminum varnish, xanthan gum, yellow iron oxide, indigo karma dye aluminum varnish m)
Dosage and Administration
Inside. Adults and adolescents aged 12 years and older, the drug Lordestine is prescribed at a dose of 5 mg (1 tablet) 1 time / day.
The drug is recommended to be taken at the same time of the day, regardless of the meal, with a small amount of water. Lordestine tablets should be swallowed whole without chewing.
In chronic renal and hepatic insufficiency, dosage adjustment is required: an initial dose of 5 mg is recommended to be taken every other day (according to pharmacokinetics).
Dosing recommendations for children with chronic renal and hepatic insufficiency are not available due to insufficient data.
Side effects
The most common side effects: fatigue (1.2%), dry mouth (8%), headache (0.6%).
Side effects from post-market research.
From the side of the central nervous system: dizziness, hallucinations, psychomotor hyperreactivity, insomnia, drowsiness.
From the cardiovascular system: tachycardia, palpitations.
From the digestive system: abdominal pain, dyspepsia (including nausea, vomiting, diarrhea), hyperbilirubinemia, increased activity of liver enzymes, hepatitis.
Allergic reactions: skin rash, itching, urticaria, angioedema, anaphylactic shock.
Other: dysmenorrhea, fatigue, myalgia.
Storage conditions out of reach of children, at a temperature not higher than 25 C. pfp6177 pf10pc Ketoconazole, erythromycin, azithromycin, fluoxetine and cimetidine showed no clinically significant changes in plasma concentration of desloratadine.
lordestine does not enhance the inhibitory effect of ethanol on psychomotor function.
Overdose
Drowsiness is noted with an overdose.
Treatment: gastric lavage, activated charcoal, symptomatic therapy.
The drug is not excreted by hemodialysis.
The effectiveness of peritoneal dialysis has not been established.
Expiration
2 years.
Deystvuyuschee substances
desloratadine
tablet form
Appointment
Adult, Children over 12f6p1626p16p16p16p16 Adults, Children over 12 years old
Indications
edema of the nasal mucosa, skin itching, hay fever, dermatitis, allergy, diathesis, urticaria, allergic conjunctivitis, allergic rhinitis, Conjunctivitis
Possible product names
LORDESTIN 0.005 N30 TABLE P / O
Lordestine 5mg Tab. p / pl / rev X30
LORDESTIN 5MG. No. 30 TAB. P / O / GEDEON RICHTER /
Lordestine tab p / o 5mg x 30
Lordestin tab p / p / o 5mg N30 (pack control N10x3)
Tablets.
Packing
30 pcs.
Pharmacological action
LORDESTINE - a blocker of histamine H1 receptors (long-acting). It is the primary active metabolite of loratadine.
Inhibits the release of histamine and leukotriene C4 from mast cells.
Prevents development and facilitates the course of allergic reactions. It has anti-allergic, antipruritic and anti-exudative action.
Reduces the permeability of capillaries, prevents the development of tissue edema, relieves spasm of smooth muscles.
Almost no sedative effect and when taken in a dose of 7.5 mg does not affect the speed of psychomotor reactions.
In comparative studies of desloratadine and loratadine, there were no qualitative or quantitative differences in the toxicity of the two drugs in comparable doses (taking into account the concentration of desloratadine).
Indications
Seasonal allergic rhinitis, chronic idiopathic urticaria.
Contraindications
Pregnancy, lactation, children under 2 years of age, hypersensitivity to desloratadine.
Special instructions
Influence on the ability to drive vehicles and control mechanisms
No effect of Lordestine when used in recommended doses on the ability to drive vehicles and control mechanisms. However, given that patients may experience drowsiness, caution is advised in case of side effects from the central nervous system.
Composition
Active ingredient:
desloratadine hemisulphate 5.788 (equivalent to 5 mg of desloratadine)
Excipients:
MCC - 39 mg
calcium hydrogen phosphate dihydrate - 46.712 mg
starch pregelatinized - 7 mg
silicon aerosol mgloid - colloid mgloid 1
Film sheath:
Opadry AMB yellow 80W22099 (partially hydrolyzed polyvinyl alcohol, titanium dioxide, talc, lecithin, quinoline yellow dye-based aluminum varnish, xanthan gum, yellow iron oxide, indigo karma dye aluminum varnish m)
Dosage and Administration
Inside. Adults and adolescents aged 12 years and older, the drug Lordestine is prescribed at a dose of 5 mg (1 tablet) 1 time / day.
The drug is recommended to be taken at the same time of the day, regardless of the meal, with a small amount of water. Lordestine tablets should be swallowed whole without chewing.
In chronic renal and hepatic insufficiency, dosage adjustment is required: an initial dose of 5 mg is recommended to be taken every other day (according to pharmacokinetics).
Dosing recommendations for children with chronic renal and hepatic insufficiency are not available due to insufficient data.
Side effects
The most common side effects: fatigue (1.2%), dry mouth (8%), headache (0.6%).
Side effects from post-market research.
From the side of the central nervous system: dizziness, hallucinations, psychomotor hyperreactivity, insomnia, drowsiness.
From the cardiovascular system: tachycardia, palpitations.
From the digestive system: abdominal pain, dyspepsia (including nausea, vomiting, diarrhea), hyperbilirubinemia, increased activity of liver enzymes, hepatitis.
Allergic reactions: skin rash, itching, urticaria, angioedema, anaphylactic shock.
Other: dysmenorrhea, fatigue, myalgia.
Storage conditions out of reach of children, at a temperature not higher than 25 C. pfp6177 pf10pc Ketoconazole, erythromycin, azithromycin, fluoxetine and cimetidine showed no clinically significant changes in plasma concentration of desloratadine.
lordestine does not enhance the inhibitory effect of ethanol on psychomotor function.
Overdose
Drowsiness is noted with an overdose.
Treatment: gastric lavage, activated charcoal, symptomatic therapy.
The drug is not excreted by hemodialysis.
The effectiveness of peritoneal dialysis has not been established.
Expiration
2 years.
Deystvuyuschee substances
desloratadine
tablet form
Appointment
Adult, Children over 12f6p1626p16p16p16p16 Adults, Children over 12 years old
Indications
edema of the nasal mucosa, skin itching, hay fever, dermatitis, allergy, diathesis, urticaria, allergic conjunctivitis, allergic rhinitis, Conjunctivitis
Possible product names
LORDESTIN 0.005 N30 TABLE P / O
Lordestine 5mg Tab. p / pl / rev X30
LORDESTIN 5MG. No. 30 TAB. P / O / GEDEON RICHTER /
Lordestine tab p / o 5mg x 30
Lordestin tab p / p / o 5mg N30 (pack control N10x3)
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