Cetirizine | Zyrtec drops for oral administration 10 mg / ml, 10 ml
Special Price
$14.55
Regular Price
$23.00
In stock
SKU
BID462957
Release form
Drops for oral administration.
Drops for oral administration.
Release form
Drops for oral administration.
Packing
Bottle of 10 ml.
Pharmacological action
Zyrtec is a selective antagonist of peripheral histamine H1 receptors, a metabolite of hydroxyzine. It has anti-allergic effect, inhibiting the late phase of migration of cells involved in the inflammatory reaction (mainly eosinophils) also reduces the expression of adhesion molecules, such as ICAM-1 and VCAM-1, which are markers of allergic inflammation. It inhibits the action of other mediators and inducers of histamine secretion, such as PAF (platelet-activating factor) and the substance P.
Zirtek suppresses skin reactions in patients with cold urticaria and dermographism. When using the drug in a dose of 5 to 10 mg in patients with mild asthma, the development of bronchospasm caused by a high concentration of histamine administered as an aerosol was almost completely blocked.
A six-week study in 168 patients with allergic rhinitis in combination with mild to moderate bronchial asthma demonstrated the effectiveness of cetirizine at a dose of 10 mg for rhinitis and showed the safety of cetirizine in patients with allergic rhinitis and mild to moderate bronchial asthma.
The administration of cetirizine in doses exceeding 6 times the daily therapeutic dose (60 mg / day), and placebo as a control for 7 days, did not reveal an extension of the QT interval on the ECG.
The action of the drug begins 20 minutes after a single dose of 10 mg in a single dose in 50% of patients and after 1 h in 95% of patients, and tolerance to its antihistamine effect is not observed for 24 hours. The skin restores its normal reactivity to histamine 3 days after discontinuation of the drug.
The use of Zyrtec in therapeutic doses of 10 mg / day improved the quality of life of patients with year-round and seasonal allergic rhinitis.
Indications
For adults and children 1 year of age and older, treatment of symptoms: - year-round and seasonal allergic rhinitis and allergic conjunctivitis, such as itching, sneezing, rhinorrhea, lacrimation, conjunctival hyperemia
- hay fever (hay fever)
- urticaria (including chronic idiopathic urticaria) and Quincke edema
- other allergic dermatoses accompanied by itching and rashes.
Contraindications
Hypersensitivity to the drug or hydroxyzine.
Use during pregnancy and lactation
It is preferable to refrain from using Zyrtec during pregnancy.
Since cetirizine is excreted in breast milk, if you need to prescribe the drug during lactation, you should decide whether to stop breastfeeding.
In experimental studies, the teratogenic or embryotoxic effect of the drug was not established.
Special instructions
When used in recommended doses, Zyrtec does not increase the effect of alcohol (when its content in the blood is up to 0.5 g / l), it is nevertheless recommended to refrain from drinking alcohol while using Zyrtek.
Influence on the ability to drive vehicles and control mechanisms
Objective methods for studying the ability to engage in potentially hazardous activities did not reliably reveal any adverse effects when using the drug at a recommended dose of 10 mg.
Composition
1 ml (20 drops) contains cetirizine hydrochloride 10 mg
excipients: glycerol propylene glycol sodium saccharin methyl parahydroxybenzoate sodium acetate acetic acid water.
Dosage and administration
The drug is prescribed orally.
Children aged 1 to 2 years are prescribed 2.5 mg (5 drops) 2 times / day.
Children aged 2 to 6 years are prescribed 2.5 mg (5 drops) 2 times / day or 5 mg (10 drops) 1 time / day.
Side effects
From the digestive system: dry mouth in some cases - dyspepsia.
From the side of the central nervous system: mild and rapidly passing drowsiness, headache, fatigue in some cases are possible - agitation.
Allergic reactions: in some cases, skin rashes, angioedema.
The drug is generally well tolerated. Side effects are rare, usually have a mild and transient character.
Storage conditions
Drop solution should be stored at room temperature (15 ° to 25 РC).
Terms and conditions
without prescription
dosage form
oral drops
Appointment
For children over 1 year, 77 Adult
Indications
Urticaria, Pollinosis, Allergy, Dermatitis, Skin itching, Diathesis, Quinke swelling, Allergic conjunctivitis, Neurodermatitis, Allergic rhinitis t, Dermatosis
USB Farma SA, Belgium
Drops for oral administration.
Packing
Bottle of 10 ml.
Pharmacological action
Zyrtec is a selective antagonist of peripheral histamine H1 receptors, a metabolite of hydroxyzine. It has anti-allergic effect, inhibiting the late phase of migration of cells involved in the inflammatory reaction (mainly eosinophils) also reduces the expression of adhesion molecules, such as ICAM-1 and VCAM-1, which are markers of allergic inflammation. It inhibits the action of other mediators and inducers of histamine secretion, such as PAF (platelet-activating factor) and the substance P.
Zirtek suppresses skin reactions in patients with cold urticaria and dermographism. When using the drug in a dose of 5 to 10 mg in patients with mild asthma, the development of bronchospasm caused by a high concentration of histamine administered as an aerosol was almost completely blocked.
A six-week study in 168 patients with allergic rhinitis in combination with mild to moderate bronchial asthma demonstrated the effectiveness of cetirizine at a dose of 10 mg for rhinitis and showed the safety of cetirizine in patients with allergic rhinitis and mild to moderate bronchial asthma.
The administration of cetirizine in doses exceeding 6 times the daily therapeutic dose (60 mg / day), and placebo as a control for 7 days, did not reveal an extension of the QT interval on the ECG.
The action of the drug begins 20 minutes after a single dose of 10 mg in a single dose in 50% of patients and after 1 h in 95% of patients, and tolerance to its antihistamine effect is not observed for 24 hours. The skin restores its normal reactivity to histamine 3 days after discontinuation of the drug.
The use of Zyrtec in therapeutic doses of 10 mg / day improved the quality of life of patients with year-round and seasonal allergic rhinitis.
Indications
For adults and children 1 year of age and older, treatment of symptoms: - year-round and seasonal allergic rhinitis and allergic conjunctivitis, such as itching, sneezing, rhinorrhea, lacrimation, conjunctival hyperemia
- hay fever (hay fever)
- urticaria (including chronic idiopathic urticaria) and Quincke edema
- other allergic dermatoses accompanied by itching and rashes.
Contraindications
Hypersensitivity to the drug or hydroxyzine.
Use during pregnancy and lactation
It is preferable to refrain from using Zyrtec during pregnancy.
Since cetirizine is excreted in breast milk, if you need to prescribe the drug during lactation, you should decide whether to stop breastfeeding.
In experimental studies, the teratogenic or embryotoxic effect of the drug was not established.
Special instructions
When used in recommended doses, Zyrtec does not increase the effect of alcohol (when its content in the blood is up to 0.5 g / l), it is nevertheless recommended to refrain from drinking alcohol while using Zyrtek.
Influence on the ability to drive vehicles and control mechanisms
Objective methods for studying the ability to engage in potentially hazardous activities did not reliably reveal any adverse effects when using the drug at a recommended dose of 10 mg.
Composition
1 ml (20 drops) contains cetirizine hydrochloride 10 mg
excipients: glycerol propylene glycol sodium saccharin methyl parahydroxybenzoate sodium acetate acetic acid water.
Dosage and administration
The drug is prescribed orally.
Children aged 1 to 2 years are prescribed 2.5 mg (5 drops) 2 times / day.
Children aged 2 to 6 years are prescribed 2.5 mg (5 drops) 2 times / day or 5 mg (10 drops) 1 time / day.
Side effects
From the digestive system: dry mouth in some cases - dyspepsia.
From the side of the central nervous system: mild and rapidly passing drowsiness, headache, fatigue in some cases are possible - agitation.
Allergic reactions: in some cases, skin rashes, angioedema.
The drug is generally well tolerated. Side effects are rare, usually have a mild and transient character.
Storage conditions
Drop solution should be stored at room temperature (15 ° to 25 РC).
Terms and conditions
without prescription
dosage form
oral drops
Appointment
For children over 1 year, 77 Adult
Indications
Urticaria, Pollinosis, Allergy, Dermatitis, Skin itching, Diathesis, Quinke swelling, Allergic conjunctivitis, Neurodermatitis, Allergic rhinitis t, Dermatosis
USB Farma SA, Belgium
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