calcium carbonate, Kolekaltsyferol, Copper oxide, Sodium borate, Zinc oxide, Manganese sulfate | Calcemin Advance tablets, 30 pcs.

Release form

Coated tablets.



packaging 30 pcs

Pharmacological action

Combined preparation containing vitamins, micro and macro elements.

The action is determined by the properties that make up the ingredients.

Indications

Prevention and comprehensive treatment of osteoporosis of various origins:

- in women during menopause (natural and surgical)

- in people who take GCS and immunosuppressants for a long time.

Therapy of diseases of the musculoskeletal system (to improve the consolidation of traumatic fractures)

To supplement the deficiency of calcium and trace elements in adolescents.

Contraindications

Increased individual sensitivity to the components of the drug, vitamin D hypervitaminosis, hypercalcemia and hypercalciuria, severe renal failure, urolithiasis, nephrolthiasis, active tuberculosis, sarcoidosis, childhood (up to 12 years old), allergic reaction, allergic reaction since the composition of the drug includes soy polysaccharide.

Precautions:

Period of pregnancy and lactation, renal failure.

Composition

Active ingredients:

calcium (calcium citrate and calcium carbonate) 500 mg,

colecalciferol (vitamin D3) 200 IU,

magnesium 40 mg,

zinc 7.5 mg,

copper 1 mg,

copper 1 mg,

mg,

boron 250 mcg.

Excipients:

maltodextrin 25 mg,

microcrystalline cellulose 49.05 mg,

croscarmellose sodium 38 mg,

stearic acid 16, 3 mg,

soybean polysaccharide 15 mg, sodium lauric sulfide 5 mg.

Shell:

hypromellose 26, 328 mg,

titanium dioxide 12, 643 mg,

magnesium silicate 5 mg,

triacetin 5, 689 mg,

mineral oil 2, 845 mg,

dye red No. 40 (charming red dye) 0, 316,

dye yellow No. 6 (sunny sunset yellow) 079 mg,

dye blue No. 1 0.04 mg.

Description:

Oval biconvex tablets, coated with a pink shell with a notch on one side.

Dosage and Administration

Take orally with food.

Complex treatment of osteoporosis - 1 tablet 2 times a day.

Prevention of osteoporosis - 1 tablet per day.

When using the drug for the prevention and in the treatment of osteoporosis, the duration of treatment is determined individually by the doctor. The average duration of the course for prevention is 2 months, for the treatment of osteoporosis - 3 months.

Therapy of diseases of the musculoskeletal system: to improve the consolidation of traumatic fractures - 1 tablet per day, the duration of treatment is 4-6 weeks.

To supplement the deficiency of calcium and trace elements in adolescents from 12 years old - 1 tablet per day. The average duration of treatment is 4-6 weeks.

Side effects

Nausea, vomiting, flatulence, diarrhea, constipation, hypercalcemia, hypercalciuria, allergic reactions (pruritus, rash, urticaria).

Drug Interaction

When administered with Calcemin with vitamin A, vitamin D3 toxicity is reduced. Phenytoin, barbiturates, ACS reduce the effectiveness of vitamin D3.

Laxatives reduce the absorption of vitamin D3. GCS, hormonal contraceptives for systemic use, levothyroxine worsen the absorption of calcium ions. With tetracyclines, the interval between doses should be at least 3 h, bisphosphonates and sodium fluoride (their absorption is impaired) - not less than 2 h. With the combined use of the drug Calzemin with cardiac glycosides, their toxicity is increased (control of ECG and clinical condition is necessary), with thiazide diuretics - the risk of developing hyperkilemia is increased. - increased excretion of calcium by the kidneys. Calcium should not be used concomitantly with calcium channel blockers.

Co-administration with aluminum-containing antacids is not recommended due to their reduced efficacy.

Overdose

Vitamin D hypervitaminosis, hypercalcemia and hypercalciuria.

Symptoms: decreased appetite, thirst, polyuria, dizziness, fainting, constipation, nausea and vomiting, muscle weakness, headache, coma, fatigue, bone pain, mental disorders, nephrocalcinosis, abdominal pain, urolithiasis, in severe cases - cardiac arrhythmias.

With prolonged use in doses above 2500 mg calcium - kidney damage, soft tissue calcification.

In case of detection of the first signs of overdose, it is necessary to reduce the dose or stop the use of the drug, see a doctor.

In case of hypercalciuria exceeding 7.5 mmol / day (300 mg / day), it is necessary to reduce the dose or discontinue the drug.

Treatment: rehydration, use of loop diuretics (eg furosemide), glucocorticosteroids, calcitonin, bisphosphonates, in severe cases, hemodialysis.

If you accidentally overdose, you should induce vomiting and wash your stomach. Therapy is symptomatic.

It is therefore necessary to reduce the dose or discontinue the drug. In case of accidental overdose, it is necessary to induce vomiting, to wash the stomach. Therapy is symptomatic.

Storage conditions

At a temperature not exceeding 25 C.

Keep out of the reach of children.

The Expiration of

is 3 years. Do not use after the expiry date.

Terms of delivery from

pharmacy without a prescription

Dosage form

dosage form

tablets

Bayer Pharma AG, Germany