Betamethasone, Gentamicin | Celestoderm B with Garamycin Ointment 0.1%, 30 g

Special Price $23.28 Regular Price $32.00
In stock
SKU
BID462743
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Release form

Ointment.
Release form

Ointment.

Packing

Tube 30 g

Pharmacological action of

Celestoderm-B contains betamethasone valerate and gentamicin.

Betamethasone valerate - a glucocorticosteroid (GCS), has anti-inflammatory and anti-allergic effects, inhibits the release of cytokines and inflammatory mediators, reduces the metabolism of arachidonic acid, induces the formation of lipocortins with decongestant activity, and reduces vascular permeability.

Gentamicin - a broad-spectrum antibiotic - when applied topically, it is effective against most common pathogens.

Indications

Topical treatment of wet or oily skin diseases amenable to corticosteroids, in the presence of a secondary infection caused by microorganisms susceptible to gentamicin, or if such infection is suspected:

- Eczema (atopic, pediatric, coin-like).

- Contact dermatitis.

- Seborrheic dermatitis.

- Neurodermatitis.

- Solar dermatitis.

- Exfoliative dermatitis.

- Radiation dermatitis.

- Diaper rash.

- Psoriasis.

- Anogenital itching.

- Senile itching.

Contraindications

- Hypersensitivity to any of the components of the drug.

- Tuberculosis of the skin.

- Cutaneous manifestations of syphilis.

- Chicken pox.

- Cold sores.

- Fungal skin diseases.

- The vaccination period and skin post-vaccination reactions.

- Lactation.

- Pregnancy (long-term treatment of large areas of the skin).

- Children under 6 months of age.

Precautions:

- Pregnancy (in the absence of criteria for contraindication), especially in the 1st trimester.

- Long-term treatment of large areas of the skin, especially in children.

- In the presence of skin cracks or the use of occlusive dressings.

Use during pregnancy and lactation

Due to the fact that the safety of the use of local corticosteroids in pregnant women has not been established, the appointment of drugs of this class during pregnancy is justified only if the benefit to the mother clearly exceeds the possible harm to the fetus.

GCS should not be used during pregnancy for long periods or in large doses.

Since it has not yet been established whether corticosteroids, with topical application and systemic absorption, can pass into breast milk, a decision should be made whether to stop breastfeeding or to discontinue the drug, taking into account how necessary its use for the mother.

Special instructions

Celestoderm B is not intended for use in ophthalmology.

When using the drug on large surfaces and / or with an occlusive dressing, it is necessary to bear in mind the possibility of a systemic effect of betamethasone, as well as the development of the following side effects: maceration of the skin, attachment of a secondary infection, atrophy of the skin, striae, sweating.

If bacterial and fungal microflora resistant to the drug appear, discontinue use of the drug and prescribe appropriate therapy.

Use in pediatrics

For children, the drug is prescribed only according to strict indications and under medical supervision, as possible development of systemic side effects associated with betamethasone: suppression of the function of the hypothalamic-pituitary-adrenal system and the development of symptoms of hypercorticism. In addition, there may be a decrease in the excretion of growth hormones, as well as an increase in intracranial pressure.

Composition

1 g contains:

betamethasone 17 - valerate (equivalent to 1 mg betamethasone),

gentamicin sulfate (equivalent to 1 mg of gentamicin base).

Dosage and Administration

Externally. Apply a thin layer to the affected areas of the skin 2 times a day - in the morning and in the evening.

Frequency of use, other than recommended, can be determined by the doctor, focusing on the severity of the disease.

In mild cases, once-daily use is usually sufficient, with more severe lesions, more frequent use may be required.

Overdose

Symptoms: Excessive or prolonged use of local corticosteroids can inhibit the function of the pituitary-adrenal system, which can lead to the development of secondary insufficiency of the adrenal cortex and the appearance of symptoms of hypercorticism, including Cushing's syndrome. A single overdose of gentamicin is not accompanied by the appearance of any symptoms. Long-term use in doses exceeding recommended can lead to a significant increase in insensitive flora, including fungal, in the lesion.

Treatment: appropriate symptomatic treatment is indicated. The acute symptoms of hypercorticism are usually reversible. If necessary, correction of electrolyte imbalance is indicated. In case of chronic toxic effects, gradual withdrawal of corticosteroids is recommended. With uncontrolled growth of microorganisms, appropriate antibacterial or antifungal treatment should be selected.

Storage conditions

Store at a temperature not exceeding 25 РC.

Active ingredient

Betamethasone, Gentamicin

Dosage form

ointment d14rewaf463636 i form

ointment

Bayer Pharma AG, Germany

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