betahistine | Betagistin Canon tablets 8 mg 30 pcs.

Packing

30 pcs

Pharmacological action

Betagistin - histaminergic, improves microcirculation.

Pharmacodynamics

Agonist of H1 receptors of vessels of the inner ear and antagonist of H3 receptors of the vestibular nuclei of the central nervous system Through direct agonistic action on the H1 receptors of the vessels of the inner ear, as well as indirectly through the action on the H3 receptors, it improves microcirculation and capillary permeability, normalizes endolymph pressure in the labyrinth and cochlea, and increases blood flow in the basilar artery.

It has a pronounced central effect, being an inhibitor of the H3 receptors of the vestibular nerve nuclei. It improves the conductivity in the neurons of the vestibular nuclei at the level of the brain stem.

The clinical manifestation of these properties is a decrease in the frequency and intensity of dizziness, decrease in tinnitus, improvement in hearing if it is reduced.

Pharmacokinetics

Absorbed rapidly, binding to plasma proteins is low. The time required to reach Cmax is 3 hours.

It is almost completely excreted by the kidneys as a metabolite (2-pyridylacetic acid) within 24 hours. T1 / 2 - 3-4 hours.

Indications

treatment and prevention of vestibular dizziness of various origins

syndromes, including dizziness and headache, tinnitus, progressive hearing loss, nausea and vomiting

disease or Meniere's syndrome.

Use during pregnancy and lactation

Insufficient data to evaluate the effects of the drug during pregnancy and lactation. In this regard, it is not recommended to take during pregnancy. At the time of treatment, it is necessary to stop breastfeeding.

Composition

1 tablet contains:

Active ingredient: betahistine dihydrochloride 8 mg

Excipients: MCC lactose (milk sugar) citric acid silicon monohydrate colloidal dioxide (aerosil) crospovidone talc magnesium stearate.

Dosage and Administration

Inside, with food. 1 / 2-1 tablets 3 times a day.

Improvement is usually noted already at the beginning of therapy. A stable therapeutic effect occurs after two weeks of treatment and can increase over several months of treatment. The treatment is long. The duration of the drug is selected individually.

Side effects

Gastrointestinal disturbances, the appearance of hypersensitivity reactions from the skin (rash. itching. urticaria), Quincke's edema.

Overdose

Symptoms: nausea, vomiting, cramps.

Treatment: gastric lavage, intake of activated carbon, symptomatic therapy.

Storage Conditions

In a dry, dark place at a temperature not exceeding 25 РC. Keep out of reach of children.

Expiration

2 years.

active substance

Betahistine

Terms leave through pharmacies

In retseptu

The dosage form of

tablet

Prescription

For adults as prescribed by a doctor

Indications

Indications

cerebrovascular disease Meniere

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